scholarly journals Bruises around the umbilicus in an infant

2016 ◽  
Vol 8 (3) ◽  
Author(s):  
Sam Hassan ◽  
Ghassan Nakib ◽  
Mary J. Saviour
Keyword(s):  
Silver Nitrate ◽  
Topical Application ◽  
Congenital Abnormality ◽  
Surgical Intervention ◽  
Histopathological Examination ◽  
Pancreatic Tissue ◽  
Duct Cyst ◽  
Omphalomesenteric Duct ◽  
Common Causes ◽  
First Time

The most common causes of umbilical discharge in infancy are infection and umbilical granuloma that may be treated by antibiotics and topical application of silver nitrate subsequently. If the umbilical discharge persists or if there is any abnormal discoloration around the umbilicus, it is important to investigate for underlying congenital abnormality that may be cured by surgical intervention. Unusual presentation of omphalomesenteric duct cyst has been reported in literature. We report, for the first time as far as our search is concerned, a case of a 16-month-old infant who presented initially with persistent umbilical discharge and finally with bruising around the umbilicus in keeping with Cullen’s sign. A diagnosis of omphalomesenteric duct cyst containing pancreatic tissue was made on histopathological examination. This case emphasizes that, a persistent umbilical discharge and or discoloration around the umbilicus should be further investigated and an omphalomesenteric duct cyst can present as Cullen’s sign.

scholarly journals Persistent Umbilical Discharge from an Omphalomesenteric Duct Cyst Containing Gastric Mucosa

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Kanimozhi Tamilselvan ◽  
Arunodaya Mohan ◽  
Sarah Cheslyn-Curtis ◽  
Michael Eisenhut
Keyword(s):  
Gastric Mucosa ◽  
Gastric Acid ◽  
Congenital Abnormality ◽  
Surgical Intervention ◽  
Ectopic Gastric Mucosa ◽  
Surgical Removal ◽  
Duct Cyst ◽  
Omphalomesenteric Duct ◽  
First Case

Umbilical discharge in infancy is often attributed to infection or an umbilical granuloma. It is important to investigate if such a discharge is due to an underlying congenital abnormality because corrective surgical intervention may then be required. We present the first case of an infant with a persistent umbilical discharge from an omphalomesenteric duct cyst. The discharge was associated with periumbilical dermatitis. The dermatitis was most likely due to irritation of the skin by gastric acid produced by the ectopic gastric mucosa contained in the omphalomesenteric duct cyst. Both discharge and dermatitis resolved after surgical removal of the cyst.

Internal herniation due to an omphalomesenteric duct cyst in a 69-year-old man

2015 ◽  
Vol 53 (09) ◽  
pp. 1084-1086
Author(s):  
S. Suh ◽  
Y. Choi ◽  
S. Lee ◽  
H. Kang
Keyword(s):  
Internal Herniation ◽  
Duct Cyst ◽  
Omphalomesenteric Duct

scholarly journals Effect of the Total Extract of Averrhoacarambola (Oxalidaceae) Root on the Expression Levels of TLR4 and NF-κB in Streptozotocin-Induced Diabetic Mice

2015 ◽  
Vol 36 (6) ◽  
pp. 2307-2316 ◽  
Author(s):  
Xiaohui Xu ◽  
Tao Liang ◽  
Xing Lin ◽  
Qingwei Wen ◽  
Xingmei Liang ◽  
...  
Keyword(s):  
Body Weight ◽  
Histopathological Examination ◽  
Fasting Blood Glucose ◽  
Folk Medicine ◽  
Immunohistochemical Analysis ◽  
Tissue Expression ◽  
Pancreatic Tissue ◽  
Diabetic Mice ◽  
Total Extract ◽  
Expression Levels

Background: Averrhoacarambola L., which is a folk medicine used in diabetes mellitus (DM) in ancient China, has been reported to have anti-diabetic efficacy. Aims: The aim of this study was to evaluate the hypoglycemic effect of the extract of Averrhoacarambola L. root (EACR) on the regulation of the Toll-like receptor 4 (TLR4)-Nuclear-factor kappa B (NF-κB) pathway in B) pathway in streptozotocin (STZ)-induced diabetic mice. Methods: the mice were injected with STZ (120 mg/kg body weight) via a tail vein. After 72 h, the mice with FBG = 11.1 mmol/L were confirmed as having diabetes. Subsequently, the mice were treated intragastrically with EACR (300, 600, 1200 mg/kg body weight/d) and metformin (320 mg/kg body weight/d) for 14 days. Results: As a result the serum fasting blood glucose (FBG), interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a) levels were decreased following EACR administration. Immunohistochemical analysis revealed that the pancreatic tissue expression levels of TLR4 and NF-κB were downregulated after EACR administration. EACR suppressed pancreatic mRNA expression level of TLR4 and blocked the downstream NF-κB pathway in the pancreas. According to Western blot analysis EACR suppressed pancreatic TLR4 and NF-κB protein expression levels. Histopathological examination of the pancreas showed that STZ-induced pancreas lesions were alleviated by the EACR treatment. Conclusion: These findings suggest that the modulation of the IL-6 and TNF-a inflammatory cytokines and the suppression of the TLR4-NF-κB pathway are most likely involved in the anti-hyperglycemic effect of EACR in STZ-induced diabetic mice.

A RARE CASE OF HETEROTOPIC PANCREATIC TISSUE CAUSING SMALL BOWEL OBSTRUCTION

2021 ◽  
pp. 4-5
Author(s):  
B. Santhi ◽  
M. Annapoorani ◽  
Sharada bhavana
Keyword(s):  
Intestinal Obstruction ◽  
Rare Case ◽  
Histopathological Examination ◽  
Pancreatic Tissue ◽  
Acute Intestinal Obstruction ◽  
Emergency Laparotomy ◽  
Review Of Literature ◽  
Heterotopic Pancreatic Tissue ◽  
Small Growth ◽  
Upper Gastrointestinal

A Rare case of heterotopic pancreatic tissue of ileum causing acute intestinal obstruction has been described with a brief review of literature. A 42 yr old male patient presented to the emergency department with features of acute intestinal obstruction. After evaluation patient was taken up for emergency laparotomy which revealed a band to be arising from ileum. Furthermore, there was a small growth in the ileal wall at the site of origin of the band. Hence resection of the growth was done and followed by ileoileal anastomosis. Later on, histopathological examination of the growth revealed it to be heterotopic pancreatic tissue. Heterotopic pancreatic tissue is often an incidental nding encountered in upper gastrointestinal tract during endoscopy and surgeries. But Symptomatic ectopic pancreas of ileum is relatively rare and they very rarely present with acute symptoms as in this case

scholarly journals Prevalence and pattern of neck masses in pediatric patient: in Aseer Central Hospital, KSA

2017 ◽  
Vol 3 (4) ◽  
pp. 791
Author(s):  
Jibril Yahya Hudise ◽  
Khalid Ali Alshehri ◽  
Radeif Eissa Shamakhey ◽  
Ali Khalid Alshehri
Keyword(s):  
Pediatric Patient ◽  
Histopathological Examination ◽  
Statistical Tests ◽  
Age Groups ◽  
Neck Mass ◽  
Anatomical Location ◽  
Histopathological Diagnosis ◽  
Central Hospital ◽  
Duct Cyst ◽  
Neck Masses

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Neck masses are a common complaint in children worldwide, and constitute a major indication for surgical consultation in many pediatric surgical centers. Most of the neck masses in children are benign in their nature and clinical course. The broad spectrum of etiology of neck masses that ranged from congenital benign to acquired neoplastic lesions is varied and related to multiple factors. This retrospective study was done with the objective to assess the distribution of neck masses related to gender, age, pathology, and anatomical location of neck masses in Aseer Central Hospital. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">Medical records of 62 patients with neck masses were collected from the department of pathology at Aseer Central Hospital KSA. The cases were reviewed for data on gender, age, the type of origin tissue, the type of lesion, and the anatomical location. Comparison between genders, age groups, and tissue origins were performed. All statistical tests were performed with SPSS software. We exclude thyroid, parathyroid and salivary gland masses.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Over a period of 5 years, a total of 62 patients 53.2% and women 46.8% had neck masses resected for pathological assessments. The age of presentation was ranging from 1 to 14 years. 22.6% developed in (from 1 years to 5 years old), 38.7% developed in (6 to 10 years), and 38.7% developed, in (11 to 14 years). The histopathological diagnosis of the neck masses were congenital 40.3%, inflammatory 33.9%, and malignant tumor 25.8%. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">The differential diagnosis of the pediatric neck mass includes a wide array of congenital, inflammatory, benign and malignant lesions. The exact diagnosis may only be obtained by histopathological examination. In our study the most common masses in pediatric patient thyroglossal duct cyst, all midline masses are congenital.</span></p>

scholarly journals Perforation of the jejunum diverticulum: the role of CT examination

2019 ◽  
pp. 66-76
Author(s):  
I. V. Platitsyn ◽  
A. V. Kondratyev ◽  
A. V. Panin ◽  
E. M. Shubarkina ◽  
A. L. Maslov
Keyword(s):  
Small Intestine ◽  
Acute Abdomen ◽  
Research Methods ◽  
Clinical Case ◽  
Laparoscopic Resection ◽  
Surgical Intervention ◽  
Everyday Practice ◽  
Correct Interpretation ◽  
Common Causes

Uncomplicated diverticula of the small intestine are asymptomatic, extremely rare in everyday practice and, most often, are detected already with the development of complications such as perforation and abscess formation. Diagnosis of complicated diverticula of the small intestine is difficult due to many other, more common causes of acute abdomen, insufficient use of the capabilities of the methods of radiation diagnosis, the lack of application and correct interpretation of the results of instrumental and special research methods. The article presents a clinical case of perforation of the jejunum diverticulum. The results of effective MDCT diagnosis and successful surgical intervention are presented: laparoscopic resection of the jejunum with the formation of the primary hardware intracorporeal enteroentero-anastomosis side by side. 

scholarly journals Cystic form of biliary atresia. Treatment experience

2020 ◽  
Vol 10 (1) ◽  
pp. 17-24
Author(s):  
Irina I. Borisova ◽  
Anatoliy V. Kagan ◽  
Svetlana A. Karavaeva ◽  
Aleksey N. Kotin
Keyword(s):  
Surgical Treatment ◽  
Bile Duct ◽  
Common Bile Duct ◽  
Biliary Atresia ◽  
Bile Ducts ◽  
Surgical Intervention ◽  
Ultrasound Examination ◽  
Duct Cyst ◽  
Cystic Form ◽  
The Common

Background. The cystic form of biliary atresia is a rare form of atresia of the biliary tract, which is a relatively favorable variant of the defect and can be diagnosed antenatally. In practice, it is important not only to suspect this diagnosis, but also to differentiate this variant of impaired development of the external bile duct from the cyst of the common bile duct. This is due to the difference in approaches and methods of surgical treatment of choledochal cysts and biliary atresia. Obliteration (atresia) of the bile ducts in the absence of timely surgical intervention quickly leads to the progression of cirrhosis and the development of liver failure. The method of choice in the treatment of AD is Kasai surgery, often palliative in nature, but allowing to delay the time until liver transplantation. The cyst of the common bile duct rarely requires early surgical treatment, and the risk of cirrhosis is significantly lower. Surgical intervention is aimed at removing the cyst and restoring the flow of bile by anastomosing the external bile ducts with the intestines, which is a radical method of treatment and leads to the recovery of the child. External similarity in ultrasound examination of the fetus and newborn baby of the cystic form of biliary atresia of the bile ducts with a cyst of the common bile duct does not always allow differentiation of one defect from another, which can lead to untimely correction of the defect and an unfavorable outcome. Aim. Demonstrate a rare type of biliary atresia. Materials and methods. Between 2001 and 2019, 33 patients with biliary atresia were treated in the Childrens City Multidisciplinary Clinical Specialized Center for High Medical Technologies in St. Petersburg, only two patients had a cystic form. Both children were initially treated as patients with bile duct cyst. Children were operated on at the age of 2 and 3.5 months. The first patient underwent surgery Kasai, the second hepaticoyunoanastomosis. Results. During the observation period (9 years and 4 years), the synthetic function of the liver is normal, and there are currently no indications for transplantation. Conclusion. If a fetus or a newborn with neonatal jaundice is detected during ultrasound examination of a cystic formation in the gates of the liver, it is very important to correctly and quickly make a differential diagnosis between the cystic form of biliary atresia of the biliary tract and the common bile duct cyst.

scholarly journals Epistaxis: etiological profile and treatment outcome in a teaching hospital in South India

2017 ◽  
Vol 3 (4) ◽  
pp. 878
Author(s):  
Basheer N. K. ◽  
Jaya C. ◽  
Sabir V. T.
Keyword(s):  
Traffic Accidents ◽  
Surgical Intervention ◽  
Road Traffic ◽  
Treatment Options ◽  
Cost Benefit ◽  
Minor Bleeding ◽  
Older Individuals ◽  
Bleeding Point ◽  
Common Causes ◽  
Nasal Bleed

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Epistaxis is the most common otorhinolaryngological emergency worldwide. Minor bleeding episodes occur more frequently in children and adolescents, whereas severe bleed requiring otolaryngologic intervention often occur in older individuals. Treatment options can be conservative or surgical, the selection of which should be made considering the parameters: efficiency, complications, and cost-benefit. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">This was a prospective study done in 131 patients with epistaxis, in the Department of ENT, Government Medical College, Trivandrum, with the aim to determine the etiology and the outcome of the conservative and surgical management.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">The most common causes of epistaxis were trauma and hypertension. The age incidence increased after forty years and majority had unilateral, anterior nasal, mild-moderate bleed. 79% of the cases were managed by conservative measures as opposed to only 21% who required surgical intervention. Success rate of anterior nasal pack and cauterisation of bleeding point was nearly 84%. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Majority of cases of epistaxis can be successfully managed by conservative measures and surgical intervention may not be necessary in most cases. Cauterization of bleeding point is the best conservative method which can be offered to the patient though anterior nasal packing still remains the most preferred method to control the bleed. The most common causes of epistaxis being trauma and hypertension, reducing road traffic accidents and lifestyle illness can reduce the incidence of nasal bleed.</span></p>

scholarly journals Idiopathic Infected Hydrocele in a Toddler: A Case Report with Review

2006 ◽  
Vol 6 ◽  
pp. 2396-2398 ◽  
Author(s):  
Jayesh Sagar ◽  
Suhas Kumar ◽  
D. Mondal ◽  
D.K. Shah
Keyword(s):  
Case Report ◽  
Surgical Intervention ◽  
English Literature ◽  
Review Of Literature ◽  
First Time

Idiopathic infected hydrocele in infants is a rare, but well-documented, entity in English literature; however, occurrence of such a condition in a toddler is not yet documented. Here we report the case of an idiopathic infected hydrocele in a toddler for the first time in English literature. We also discuss a review of literature and demonstrate management of infected hydrocele by antibiotics without any surgical intervention, also for the first time in English literature.

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