scholarly journals Risk factors for intestinal obstruction after Ladd procedure

2015 ◽  
Vol 7 (2) ◽  
Author(s):  
Tetsuya Mitsunaga ◽  
Takeshi Saito ◽  
Keita Terui ◽  
Mitsuyuki Nakata ◽  
Sachie Ohno ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intestinal Obstruction ◽  
Digestive Disease ◽  
Intestinal Ischemia ◽  
The Other ◽  
Common Complication ◽  
Initial Operation ◽  
Ladd Procedure ◽  
Increased Risk ◽  
Causes And Risk Factors

Intestinal obstruction is a common complication after Ladd procedure. Ninety-three cases who had undergone the Ladd procedure between 1977 and 2013 treated at our own institution were retrospectively reviewed to identify the causes and risk factors for intestinal obstruction. The Ladd procedure has been performed without any intestinal fixing. Of the 87 cases who survived to discharge, intestinal obstruction was observed in 22 (25.3%). Among the cases with intestinal obstruction, 13 (59.1%) showed intestinal ischemia at the initial operation; this incidence was notably high, although it is low when only those cases with another concurrent surgical digestive disease are considered. All cases of intestinal obstruction were caused not by recurrent volvulus, but by adhesion between the intestine and the mesentery. Intestinal fixing is not required to prevent recurrent volvulus, but it is important to achieve adequate widening of the mesenteric base. The risk of intestinal obstruction after the Ladd procedure, on the other hand, is high. Moreover, patients with intestinal ischemia have an increased risk of intestinal obstruction.

Death Following Recent Admission Into Nursing Home From Community Living: A Systematic Review Into the Transition Process

2017 ◽  
Vol 30 (4) ◽  
pp. 584-604 ◽  
Author(s):  
Noha Ferrah ◽  
Joseph Elias Ibrahim ◽  
Chebiwot Kipsaina ◽  
Lyndal Bugeja
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Nursing Home ◽  
Transition Process ◽  
Status Transition ◽  
Increased Risk ◽  
Causes Of Deaths ◽  
Causes And Risk Factors ◽  
The Impact ◽  
First Admission

Objective: This study examines the impact of the transition process on the mortality of elderly individuals following their first admission to nursing home from the community at 1, 3, and 6 months postadmission, and causes and risk factors for death. Method: A systematic review of relevant studies published between 2000 and 2015 was conducted using key search terms: first admission, death, and nursing homes. Results: Eleven cohort studies met the inclusion criteria. Mortality within the first 6 month postadmission varied from 0% to 34% (median = 20.2). Causes of deaths were not reported. Heightened mortality was not wholly explained by intrinsic resident factors. Only two studies investigated the influence of facility factors, and found an increased risk in facilities with high antipsychotics use. Discussion: Mortality in the immediate period following admission may not simply be due to an individual’s health status. Transition processes and facility characteristics are potentially independent and modifiable risk factors.

scholarly journals Cancer-Associated Thrombosis: An Overview of Mechanisms, Risk Factors, and Treatment

Cancers ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 380 ◽  
Author(s):  
Norbaini Abdol Razak ◽  
Gabrielle Jones ◽  
Mayank Bhandari ◽  
Michael Berndt ◽  
Pat Metharom
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Current Treatment ◽  
Host Cells ◽  
Coagulation Cascade ◽  
Common Complication ◽  
Increased Risk ◽  
Thrombotic Complications ◽  
Cancer Associated Thrombosis

Cancer-associated thrombosis is a major cause of mortality in cancer patients, the most common type being venous thromboembolism (VTE). Several risk factors for developing VTE also coexist with cancer patients, such as chemotherapy and immobilisation, contributing to the increased risk cancer patients have of developing VTE compared with non-cancer patients. Cancer cells are capable of activating the coagulation cascade and other prothrombotic properties of host cells, and many anticancer treatments themselves are being described as additional mechanisms for promoting VTE. This review will give an overview of the main thrombotic complications in cancer patients and outline the risk factors for cancer patients developing cancer-associated thrombosis, focusing on VTE as it is the most common complication observed in cancer patients. The multiple mechanisms involved in cancer-associated thrombosis, including the role of anticancer drugs, and a brief outline of the current treatment for cancer-associated thrombosis will also be discussed.

scholarly journals Adhesive Intestinal Obstruction in Infants and Children: The Place of Conservative Treatment

ISRN Surgery ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Ahmed H. Al-Salem ◽  
Mohammad Oquaish
Keyword(s):  
Conservative Treatment ◽  
Intestinal Obstruction ◽  
Intestinal Ischemia ◽  
Infants And Children ◽  
Age Group ◽  
Pediatric Age ◽  
Initial Operation ◽  
Pediatric Age Group ◽  
Adhesive Intestinal Obstruction ◽  
In Infants And Children

Objectives. Adhesive intestinal obstruction (AIO) is rare in the pediatric age group and its treatment is still controversial. This is a retrospective review of our experience in infants and children with AIO. Patients and Methods. The records of infants and children with AIO between January 2001 and December 2010 were retrospectively reviewed for age at diagnosis, sex, initial operation, interval between initial operation and presentation, diagnosis, treatment and outcome. Results. 44 infants and children were admitted with AIO. There were 28 males and 16 females who had 46 episodes. Their ages at presentation ranged from 1 month to 12 years (mean 5.4 years), while their ages at initial operation ranged from 2 days to 12 years (mean 4.15 years). Time elapsed from initial operation to presentation ranged from 7 days to 8 years (mean 1.5 years), and 66% developed AIO within 1 year from initial operation. Appenedecectomy was the commonest operation (29.5%). Four (9%) responded to conservative treatment. The other 40 (91%) required surgical intervention. Twenty-nine had release of adhesions only, while 10 (25%) had resection of small intestines and one underwent stricturoplasty. Two developed recurrence and one died. Conclusions. AIO is rare in the pediatric age group and the majority becomes symptomatic within 1 year of operation. Appendecectomy is the commonest operation leading to AIO. The place of conservative treatment is limited and to obviate delay and decrease the chance of intestinal ischemia, they should be treated early with surgical adhesiolysis.

scholarly journals Deaths in young people after contact with the youth justice system: a retrospective data linkage study

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Stuart Kinner ◽  
Holly Tibble ◽  
Katie Hail-Jares ◽  
Rohan Borschmann ◽  
Matthew Spittal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young People ◽  
Health Outcomes ◽  
Justice System ◽  
Cox Regression ◽  
Linkage Study ◽  
Youth Justice ◽  
Increased Risk ◽  
External Causes ◽  
Causes And Risk Factors

IntroductionYoung people who have contact with the youth justice system are distinguished by a high prevalence of complex, co-occurring health problems, including known risk factors for preventable mortality. However, almost nothing is known about health outcomes for these young people after separation from the youth justice system. Objectives and ApproachWe aimed to examine the incidence, timing, causes and risk factors for death in justice-involved young people. We linked youth justice records in Queensland, Australia 1993-2016 (N=48,963) with adult correctional records and the National Death Index. We split the cohort into three subgroups: those who had ever been in detention (n=7,643), those supervised in the community but never detained (n=12,953), and those charged with an offence but never convicted (n=28,367). We calculated all-cause and cause-specific crude mortality rates (CMRs), and indirectly standardised mortality ratios (SMRs). We used Cox regression to identify static and time-varying risk factors for death. ResultsDuring a median of 13.6 years of follow-up there were 1,452 deaths (3.0%). The all-cause CMR was 2.2 (95%CI 2.1-2.3) per 1000 person-years, and the all-cause SMR was 3.1 (95%CI 3.0-3.3). The leading external causes of death were suicide (32% of all deaths), transport accidents (16%), accidental drug-related causes (13%), and violence (3%). In adjusted analyses, independent risk factors for all-cause mortality included being male (HR=1.4, 95%CI 1.2-1.6) and older (>=15 vs. vs. charge only; HR=1.6, 95%CI 1.2-2.0) and subsequent incarceration as an adult (HR=1.8, 95%CI 1.4-2.4). Conclusion/ImplicationsYoung people who have contact with the youth justice system are at markedly increased risk of preventable death, after separation from that system. Efforts to improve long-term health outcomes for justice-involved youth have the potential to reduce preventable deaths in these highly vulnerable young people.

scholarly journals A Retrospective, Cross-Sectional Cohort Study Examining the Risk of Unintentional Fatal Drowning during Public Holidays in Australia

Safety ◽  
2018 ◽  
Vol 4 (4) ◽  
pp. 42 ◽  
Author(s):  
Paul Barnsley ◽  
Amy Peden
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Population Survey ◽  
Total Population ◽  
The Other ◽  
Cross Sectional ◽  
Life Saving ◽  
Increased Risk ◽  
Significant Difference ◽  
Public Holidays

Australia’s celebration of its public holidays often involves aquatic recreation, frequently mixed with consumption of alcohol, both of which are risk factors for drowning. This study examines how the demographics and circumstances of public holiday drownings compare to the average day drownings. A total population survey (1 July 2002 to 30 June 2017) of unintentional fatal drownings in Australia were extracted from the Royal Life Saving National Fatal Drowning Database. Date of drowning and state/territory of residence were used to determine if the drowning occurred on a public holiday in the person’s place of residence. 4175 persons drowned during the study period. There was a statistically significant difference between the incidence of fatal drowning on public holidays and the other days, with fatal drowning 1.73 times more likely to occur on public holidays (CI: 1.57–1.89). The increased risk of drowning on public holidays should inform the timing and the content of drowning prevention campaigns and strategies.

scholarly journals Detecting Self-Neglect: A Comparative Study of Indicators and Risk Factors in a Spanish Population

2019 ◽  
Vol 5 ◽  
pp. 233372141882360 ◽  
Author(s):  
Carmen Touza ◽  
Carmen Prado
Keyword(s):  
Risk Factors ◽  
Comparative Study ◽  
Social Services ◽  
Social Service ◽  
Living Conditions ◽  
The Other ◽  
Spanish Population ◽  
Personal Hygiene ◽  
Adequate Treatment ◽  
Increased Risk

Objective: To provide information relevant for detecting potential self-neglecting elders in a Spanish population. Method: This study analyzed the records of 269 social services clients. They were classified in three groups: presumed adequate treatment (AT), at increased risk of abuse (RA), and at increased risk of self-neglect (SN). Social service professionals assessed these cases. Results: Elders at SN presented greater problems in terms of their personal hygiene and appearance, their living conditions, and their ability to look after themselves, to attend to their own health, to realistically assess their situation, and to accept help from others. Variables used to classify the participants correctly predicted 91.1% of the AT cases. However, they produced incorrect predictions in the other two groups. Discussion: These results have important implications for detecting self-neglect, but they need to be confirmed with more representative population samples.

scholarly journals Intraoperative hemorrhage as a complication of cesarean myomectomy: Analysis of risk factors

2016 ◽  
Vol 73 (5) ◽  
pp. 415-421 ◽  
Author(s):  
Radmila Sparic
Keyword(s):  
Risk Factors ◽  
Control Group ◽  
Study Group ◽  
Surgical Experience ◽  
Neonatal Birth Weight ◽  
Increased Risk ◽  
Significant Difference ◽  
Cesarean Myomectomy ◽  
Risk Of Hemorrhage ◽  
Causes And Risk Factors

Background/Aim. Cesarean myomectomy is a controversial issue. It was considered relatively contraindicated for many years due to increased risk of intraoperative hemorrhage. Recent studies showed that cesarean myomectomy in some women may not be associated with increased morbidity. The aim of the study was to determine the causes and risk factors for intraoperative hemorrhage in patients subjected to cesarean myomectomy. Methods. This retrospective study included women subjected to cesarean myomectomy, divided into the study group of 36 patients in whom intraoperative hemorrhage was registered, and the control group of 66 patients in whom it was absent. The following parameters were analyzed: age, parity, gestational age of delivery, indications, type and duration of cesarean section, surgeon's experience, type, localization, size and number of myomas, number of incisions on uterus and neonatal birth weight. Results. There was a significant difference between the groups in terms of the type and size of myomas (p = 0.007 and p = 0.000, respectively) and duration of the surgery (p = 0.000). The size of the defect resulting from myoma enucleation and speed of suturing it have significant influence on the occurrence of intraoperative hemorrhage. In our study, operation on the patients of the study group lasted 14.53 minutes longer and their myomas were 39 mm bigger compared to the controls, with no difference in surgical experience of the obstetricians (p = 0.111). Conclusion. Cesarean myomectomy is associated with an increased risk of hemorrhage. Therefore, it would be advisable to discuss the hemorrhage and transfusion risks with patients with large multiple and intramural myomas before making decision to perform cesarean myomectomy. Those who perform cesarean myomectomy should be prepared to manage intraoperative hemorrhage during surgery in cases they encounter it.

Therapeutic options in male osteoporosis

2013 ◽  
Vol 22 (04) ◽  
pp. 271-276 ◽  
Author(s):  
P. Farahmand ◽  
J. D. Ringe
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Public Health Problem ◽  
Male Osteoporosis ◽  
Individual Risk ◽  
Modes Of Action ◽  
Increased Risk ◽  
Study Results ◽  
Long Term Treatment ◽  
Male Patients

SummaryOsteoporosis in men is increasingly recognized as an important public health problem but affected patients are still under-diagnosed and -treated. As in women the diagnostic and therapeutic strategy has to be adapted to the individual case. In the practical management it is very important to detect possible causes of secondary osteoporosis, to explain the possibilities of basic therapy counteracting individual risk factors and communicate that osteoporosis is a chronic disease and adherence to a long-term treatment is crucial. In established severe osteoporosis a careful analgesic therapy is important to avoid further bone loss related to immobility. In elderly men with increased risk of falling insufficient Vitamin D supply or impaired activation of Vitamin D due to renal insufficiency must be taken into consideration. Specific medications available today for the treatment of male osteoporosis comprise among antiresorptive drugs the bis phosphonates alendronate, risedronate and zoledronic acid. Denosumab, the first biological therapy is approved for men with androgen deprivation therapy for prostate cancer. An important advantage of this potent antiresorptive drug is the increased adherence due to the comfortable application by sixmonthly subcutaneous injections. Study results from the 2-year multi-center randomized controlled ADAMO-Study will very soon allow the use of denosumab in all types of male osteoporosis. Teriparatide, the 34 N-terminal amino acid sequence of parathyroid hormone was approved for men with osteoporosis as an anabolic agent based on proven efficacy by different studies. Among drugs with other modes of action the D-hormone pro-drug alfacalcidol can be used in men alone or in combination with the advantage of pleiotropic effects on calcium absorption, parathyroids, bone and muscle. Recently also Strontium-ranelate was approved for male patients with the limitation to exclude men with clinical relevant cardiovascular risk factors. In general the possibilities to treat male osteoporosis have considerably improved during recent years. Today there is a choice of a spectrum of drugs from mild to strong potency with different modes of action on bone turnover to design strategies for individual male patients.

Haematocrit: Relationships with Blood Lipids, Blood Pressure and other Cardiovascular Risk Factors

1994 ◽  
Vol 72 (01) ◽  
pp. 058-064 ◽  
Author(s):  
Goya Wannamethee ◽  
A Gerald Shaper
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Alcohol Intake ◽  
Blood Lipids ◽  
The Other ◽  
The Relationship

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.

Four-Corner Arthrodesis versus Proximal Row Carpectomy: Risk Factors and Complications Associated with Prolonged Postoperative Opioid Use

2020 ◽  
Author(s):  
Neill Y. Li ◽  
Alexander S. Kuczmarski ◽  
Andrew M. Hresko ◽  
Avi D. Goodman ◽  
Joseph A. Gil ◽  
...  
Keyword(s):  
Risk Factors ◽  
International Classification Of Diseases ◽  
Opioid Use ◽  
Proximal Row Carpectomy ◽  
Use Patterns ◽  
Patient Demographics ◽  
Implant Complications ◽  
Increased Risk ◽  
Classification Of Diseases

Abstract Introduction This article compares opioid use patterns following four-corner arthrodesis (FCA) and proximal row carpectomy (PRC) and identifies risk factors and complications associated with prolonged opioid consumption. Materials and Methods The PearlDiver Research Program was used to identify patients undergoing primary FCA (Current Procedural Terminology [CPT] codes 25820, 25825) or PRC (CPT 25215) from 2007 to 2017. Patient demographics, comorbidities, perioperative opioid use, and postoperative complications were assessed. Opioids were identified through generic drug codes while complications were defined by International Classification of Diseases, Ninth and Tenth Revisions, Clinical Modification codes. Multivariable logistic regressions were performed with p < 0.05 considered statistically significant. Results A total of 888 patients underwent FCA and 835 underwent PRC. Three months postoperatively, more FCA patients (18.0%) continued to use opioids than PRC patients (14.7%) (p = 0.033). Preoperative opioid use was the strongest risk factor for prolonged opioid use for both FCA (odds ratio [OR]: 4.91; p < 0.001) and PRC (OR: 6.33; p < 0.001). Prolonged opioid use was associated with an increased risk of implant complications (OR: 4.96; p < 0.001) and conversion to total wrist arthrodesis (OR: 3.55; p < 0.001) following FCA. Conclusion Prolonged postoperative opioid use is more frequent in patients undergoing FCA than PRC. Understanding the prevalence, risk factors, and complications associated with prolonged postoperative opioid use after these procedures may help physicians counsel patients and implement opioid minimization strategies preoperatively.

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