scholarly journals Breast ductal carcinoma in situ: a literature review of adjuvant hormonal therapy

Author(s):  
Stephen Kinsey-Trotman ◽  
Zumin Shi ◽  
Beverley Fosh

This review paper analyzed publications of adjuvant tamoxifen and aromatase inhibitor use following surgery for breast ductal carcinoma in situ (DCIS). Key endpoint analyses were risk of invasive and noninvasive malignancies and new contralateral breast cancers. Meta-analysis of three studies showed a relative risk of 0.69 (95% confidence interval, 0.60-0.79, P<0.05) for breast malignancies with tamoxifen treatment in a mixed radiotherapy treatment/naïve cohort. Subgroup analysis of DCIS populations in multiple studies showed a trend to benefit with aromatase inhibitor treatment.

2021 ◽  
pp. 101557
Author(s):  
Byung Choi ◽  
Lavandan Jegatheeswaran ◽  
Maria Nakhoul ◽  
Payal Haria ◽  
Reya Srivastava ◽  
...  

1997 ◽  
Vol 13 (3) ◽  
pp. 420-429 ◽  
Author(s):  
Xi Peng Yin ◽  
Xiao Qing Li ◽  
Duncan Neuhauser ◽  
James T. Evans

AbstractThe choice of surgical procedure for the treatment of ductal carcinoma in situ (DCIS) remains clinically based. A meta-analysis was used to synthesize the results of 24 published clinical studies. Partial breast tissue excision appears to be as efficacious as mastectomy for the treatment of DCIS of the breast.


2004 ◽  
Vol 6 (5) ◽  
Author(s):  
SB Vestey ◽  
C Sen ◽  
CJ Calder ◽  
CM Perks ◽  
M Pignatelli ◽  
...  

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