scholarly journals A case of airway aluminosis with likely secondary pleuroparenchymal fibroelastosis

2019 ◽  
Vol 14 ◽  
Author(s):  
Yuki Yabuuchi ◽  
Hitomi Goto ◽  
Mizu Nonaka ◽  
Hiroaki Tachi ◽  
Tatsuya Akiyama ◽  
...  
Keyword(s):  
Elemental Analysis ◽  
Lung Biopsy ◽  
Exertional Dyspnea ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Pleuroparenchymal Fibroelastosis ◽  
Dust Inhalation ◽  
Aluminium Powder ◽  
Aluminum Processing ◽  
Alveolar Tissue

Background: Excessive inhalation of aluminium powder occasionally results in upper lobe predominant lung fibrosis, which is similar to idiopathic pleuroparenchymal fibroelastosis (IPPFE) and has been suggested to be secondary PPFE. Case presentation: A 67-year-old man who had worked in an aluminum-processing factory for 50 years visited our hospital complaining of exertional dyspnea. Chest computed tomography (CT) showed bilateral dense sub-pleural consolidation in the upper and middle lung fields, which was consistent with IPPFE; however, the possibility of secondary PPFE associated with aluminosis was not ruled out. Considering the patient’s critical condition, trans-bronchial lung biopsy (TBLB) rather than surgical lung biopsy was performed, with elemental analysis of the biopsied specimen. Unfortunately, the specimen obtained by TBLB did not contain alveolar tissue; therefore, pathological diagnosis of PPFE was not possible. However, radiographic findings were highly suggestive of PPFE. On elemental analysis, excessive amounts of aluminum were detected in the bronchiolar walls, establishing a diagnosis of airway aluminosis with likely secondary PPFE resulting from aluminium exposure. Conclusions: TBLB with elemental analysis might be useful in differentiating idiopathic PPFE from secondary causes in dust inhalation related disease, such as aluminosis. This case indicated that inhalation of aluminium might cause secondary PPFE, with attention needing to be paid to avoid further exposure.

scholarly journals Alemtuzumab-associated diffuse alveolar damage – a case report

BMC Neurology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Antonios Bayas ◽  
Martina Menacher ◽  
Martin Schwaiblmair ◽  
Bruno Märkl ◽  
Markus Naumann
Keyword(s):  
Lung Biopsy ◽  
Respiratory Symptoms ◽  
Diffuse Alveolar Damage ◽  
Productive Cough ◽  
Exertional Dyspnea ◽  
Case Presentation ◽  
Rare Side Effect ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Abstract Background Identifying causes of alemtuzumab induced respiratory symptoms in Multiple Sclerosis (MS) patients is crucial. Case presentation We report a case of diffuse alveolar damage (DAD) in a patient with MS after the first course of alemtuzumab treatment. A 42-year-old female developed progressive non-productive cough and exertional dyspnea 2 months after alemtuzumab treatment. DAD was diagnosed histopathologically by lung biopsy. The patient recovered completely, alemtuzumab was not continued. Conclusions Our case highlights another pathomechanism for non-infective lung-disorders in alemtuzumab treated MS patients. DAD is a potential, albeit rare side effect of alemtuzumab, broadening the spectrum of non-infective lung disorders that should be considered in the diagnostic work-up.

scholarly journals Magnetic Apposition across the Epiglottis: Radiographic and Operative Correlation of a Rare Hypopharyngeal Foreign Body

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Yeli Pi ◽  
Shilpa Radhakrishnan ◽  
Yaser Alrajhi ◽  
Ravi Bhargava
Keyword(s):  
Rare Earth ◽  
Foreign Body ◽  
Interesting Case ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Rare Earth Magnet ◽  
Soft Tissue Neck ◽  
Pressure Necrosis ◽  
Magnet Ingestion ◽  
Magnetic Foreign Body

Background and Aim. Rare-earth magnet ingestions are a subset of foreign body ingestions and can result in significant morbidity secondary to pressure necrosis. These magnets are best visualized radiographically, typically located in the gastrointestinal tract. However, unusual locations of magnetic adherence may include the hypopharynx along the epiglottis, where only 2 previous cases have been reported. Clinicians should be aware of the potential dangers of rare-earth magnet ingestion and consider atypical locations of attachment in the appropriate clinical setting. Case Presentation. We present an interesting case of a fourteen-year-old female patient who presents with witnessed ingestion of multiple rare-earth magnets. Soft-tissue neck radiographs demonstrate two adjacent rounded radiopaque densities in the hypopharynx. Intraoperative images confirmed the radiographic findings and identified two magnetic balls stuck along the dorsal and ventral aspect of the epiglottis without evidence of pressure necrosis. Conclusion. This is the first published case of magnetic foreign body adherence to the epiglottis in the Radiology literature. Awareness and recognition of the unique radiographic findings of this rare entity can help clinicians streamline timely management.

scholarly journals Intraoral Sebaceous Carcinoma: Case Report of a Rare Tumor Emphasizing the Histopathological Differential Diagnosis

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Manveen Kaur Jawanda ◽  
R. V. Subramanyam ◽  
Harshaminder Grewal ◽  
Chitra Anandani ◽  
Ravi Narula
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Sebaceous Carcinoma ◽  
Rare Tumor ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Clinical Appearance ◽  
Cutaneous Malignancy ◽  
The Face ◽  
Rare Malignancy

Background. Sebaceous carcinoma (SC) is an uncommon cutaneous malignancy, usually occurring predominantly in the eyelids and only occasionally involving the oral cavity. Sebaceous carcinoma (SC) is a rare malignancy. Only 10 cases of sebaceous carcinoma of the oral cavity have been reported so far. Case Presentation. A 40-year-old female presented with a mass on the left side of the middle third of the face. Radiographic findings were inconclusive. Resection of the mass was consistent with the diagnosis of primary sebaceous carcinoma. Conclusion. Intraoral sebaceous carcinoma is uncommon. Due to its varied clinical appearance and presence of a diverse histopathologic appearance, the diagnosis is quite often confounding and elusive. Hence, it is imperative to familiarize oneself about various aspects of this rare tumor for earlier diagnosis, to improve the chances of patient’s survival.

scholarly journals Propionibacterium acnes-associated sarcoidosis complicated by acute bird-related hypersensitivity pneumonitis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Michiru Sawahata ◽  
Noritaka Sakamoto ◽  
Hideaki Yamasawa ◽  
Yuki Iijima ◽  
Hirotoshi Kawata ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Hypersensitivity Pneumonitis ◽  
Propionibacterium Acnes ◽  
Lipoteichoic Acid ◽  
Specific Monoclonal Antibody ◽  
Past Medical History ◽  
Case Presentation ◽  
Different Types ◽  
History Of ◽  
First Time

Abstract Background The number of reports on sarcoidosis complicated by hypersensitivity pneumonitis (HP) is limited, and most describe cases complicated by chronic bird-related HP. Here, we present for the first time a case with Propionibacterium acnes-associated sarcoidosis complicated by acute bird-related HP. Case presentation A 62-year-old man with a past medical history of sarcoidosis was admitted to our department, and chest computed tomography showed diffuse ground-glass opacities, which appeared as he rapidly increased the number of pigeons he kept for a competition. Random transbronchial lung biopsy revealed well-formed non-caseating epithelioid granulomas, which contained positively stained substances on immunohistochemistry using the PAB antibody, a specific monoclonal antibody against P. acnes lipoteichoic acid. Poorly formed non-caseating granulomas without positively stained substances were also detected. Conclusion We describe the successful identification of this exceptionally rare case of sarcoidosis complicated by acute bird-related HP in which two morphologically and immunohistologically different types of granulomas were present in the same lung.

scholarly journals Ameloblastic Fibroodontoma: Uncommon Case Presentation in a 6-Year-Old Child with Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Anshad Mohamed Abdulla ◽  
G. Sivadas ◽  
L. K. Surej Kumar ◽  
C. S. Sheejith Hari Peeceeyen ◽  
Vaishnavi Vedam
Keyword(s):  
Review Of The Literature ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Irregular Shapes ◽  
Odontogenic Epithelium ◽  
Ameloblastic Fibroma ◽  
Complex Odontoma ◽  
Uncommon Case ◽  
Odontogenic Neoplasm ◽  
Unerupted Teeth

Ameloblastic fibroodontoma is a benign mixed odontogenic neoplasm considered in patients with asymptomatic swelling and unerupted teeth that exhibit histologic features between ameloblastic fibroma and complex odontoma. Radiographically, this lesion appears as radiolucency admixed with focal radio opaque masses of irregular shapes and sizes. This lesion is confirmed by the presence of proliferating odontogenic epithelium, ectomesenchyme, and dental hard tissue formation on pathological analysis supplementing clinical and radiographic findings. As this tumour is less commonly seen in routine clinical practice, ameloblastic fibroodontoma with detailed orofacial features and periodic approach to its diagnosis is discussed. This paper reports a case of ameloblastic fibroodontoma of the mandible in a 6-year-old male patient with an uncommon case presentation and review of the literature.

scholarly journals A SHORT RECURRENCE TIME OF LEFT ATRIAL MYXOMA: CASE REPORT AND LITERATURE REVIEW

2021 ◽  
Vol 07 (01) ◽  
Author(s):  
KAWTAR MANOURI ◽  
Keyword(s):  
Surgical Resection ◽  
Heart Surgery ◽  
Cardiac Myxoma ◽  
Atrial Myxoma ◽  
Recurrence Time ◽  
Previous Surgery ◽  
Exertional Dyspnea ◽  
Case Presentation ◽  
Left Atrial Myxoma ◽  
Echocardiographic Image

Background: Recurrence of sporadic cardiac myxoma remains unusual but the seriousness of the situation justifies the realization of a surgical resection as complete as possible with post-operative clinical and echocargdiographic monitoring. Case presentation: We recall the case of myxoma of the left atriumin a 64-year-old women complicated by functional mitral stenosis and heart failure. She underwent urgent heart surgery, during which a friable tumor attached by a sessile base to the anterior atrial septum was removed. The postoperative effects were complicated by a pulmonary embolism. Eight months later, the patient consulted for exertional dyspnea with an echocardiographic image in favor of a recurrence of myxoma of the left atrium. Conclusion: Several mechanisms have been proposed to explain such recurrence, the most avoidable remain incomplete surgical resection and Implantation of embolic fragments of the original tumor in the myocardium due to a previous surgery.

scholarly journals A case report of idiopathic pleuroparenchymal fibroelastosis with severe respiratory failure in pregnancy

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Aiko Sekine ◽  
Kohei Seo ◽  
Satoshi Matsukura ◽  
Masaaki Sato ◽  
Aya Shinozaki-Ushiku ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Acute Exacerbation ◽  
Living Donor ◽  
Steroid Treatment ◽  
Case Presentation ◽  
Pleuroparenchymal Fibroelastosis ◽  
Chest Computed Tomography ◽  
Pulmonary Lesions ◽  
Lung Lobe ◽  
Donor Lung

Abstract Background Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a rare lung disease that manifests as parenchymal fibrosis of the upper lung lobe and pleura. There have been no reports of IPPFE complicating pregnancy. Here, we report a case of IPPFE that deteriorated rapidly during pregnancy. Case presentation A 29-year-old woman presented with dyspnea and dry cough at 19 weeks of gestation. IPPFE with acute exacerbation was suspected on chest computed tomography (CT). Despite steroid treatment, her condition progressed. A cesarean section was performed at 28 weeks of gestation. On postoperative day 26, she underwent living-donor lung transplantation. She was discharged a year after transplantation. Conclusion Our experience suggested that when pregnancy is complicated by PPFE, the disease may deteriorate rapidly. In this case, even though IPPFE with acute exacerbation was diagnosed during pregnancy, live birth was achieved, and the mother survived after lung transplantation. Lung transplantation should be considered in these patients because, once advanced, pulmonary lesions may be irreversible.

scholarly journals Pleuroparenchymal fibroelastosis: role of high-resolution computed tomography (HRCT) and CT-guided transthoracic core lung biopsy

2015 ◽  
Vol 7 (1) ◽  
pp. 155-162 ◽  
Author(s):  
Cátia Esteves ◽  
Francisco R. Costa ◽  
Margarida T. Redondo ◽  
Conceição S. Moura ◽  
Susana Guimarães ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lung Biopsy ◽  
High Resolution Computed Tomography ◽  
Ct Guided ◽  
Pleuroparenchymal Fibroelastosis

scholarly journals Management guidelines for amelogenesis imperfecta: a case report and review of the literature

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
M. Roma ◽  
Puneet Hegde ◽  
M. Durga Nandhini ◽  
Shreya Hegde
Keyword(s):  
Case Report ◽  
Treatment Plan ◽  
Rare Condition ◽  
Amelogenesis Imperfecta ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Management Guidelines ◽  
Dental Tissues ◽  
Entire Treatment

Abstract Background Rehabilitation of the entire dentition with amelogenesis imperfecta (AI) tends to pose a great challenge to the clinician. Most of the cases of amelogenesis imperfecta are reported to be associated with skeletal and dental deformities which results in severe sensitivity of the dental tissues. Case presentation This clinical case report marks out the total restoration of the oral condition of a young Indian patient diagnosed with the hypoplastic type of amelogenesis imperfecta. Fixed metal ceramic prosthesis were planned to strengthen the masticatory activity, aesthetics, to banish the dental sensitivity and to build up the general persona of the patient. The patient was followed-up at 6 months, 1 year and 2 years intervals. Functional and esthetic impairment was not visible after the follow up period and the treatment outcome was successful. The entire treatment plan was intended to enhance the functional, esthetic and the masticatory component of the occlusal architecture. Conclusion This case report details the presentation, characteristic radiographic findings, and management of a patient with an extremely rare condition of amelogenesis imperfecta.

scholarly journals Lymphoid interstitial pneumonitis in a newly diagnosed late presenter of human immunodeficiency virus infection: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
V. Petrakis ◽  
P. Panagopoulos ◽  
P. Ntolios ◽  
I. Chrysafis ◽  
M. Georgaraki ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cell Count ◽  
Interstitial Pneumonitis ◽  
Late Presenter ◽  
Newly Diagnosed ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Cd4 Cell Count ◽  
Immunodeficiency Virus ◽  
Cd4 Cell

Abstract Background An increase has been described throughout the years in the frequency of various uncommon diseases in people living with human immunodeficiency virus (HIV). Particularly late presenters are associated with a significant risk not only for acquired immune deficiency syndrome (AIDS)-defining conditions but also for non AIDS-defining diseases which aggravate the prognosis of patients. Lymphoid interstitial pneumonitis (LIP) is one of these conditions described more often after the onset of HIV epidemic. LIP is a benign polyclonal lymphoproliferative disorder of the lung with not well characterized clinical and radiographic findings. Case presentation We report the diagnostic approach and clinical progress of a newly diagnosed late presenter of HIV infection with respiratory problems in our HIV unit. The findings of computed tomography indicated the diagnosis of HIV-associated LIP, although this condition is mainly described in a normal range of CD4 cell count. Conclusion This case presentation highlights the importance of timely diagnosis and initiation of antiretroviral therapy. The increase of CD4 cell count and viral suppression may improve the symptoms of LIP.

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