scholarly journals Bioactive isochromenone isolated from Aspergillus fumigatus, endophytic fungus from Bacopa monnieri

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Jay Prakash Thakur ◽  
Rumana Haider ◽  
Dhananjay Kumar Singh ◽  
Balagani Sathish Kumar ◽  
Prema G. Vasudev ◽  
...  
Keyword(s):  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Methanol Extract ◽  
Virulent Strain ◽  
Fungal Endophytes ◽  
Biological Evaluation ◽  
Present Communication ◽  
Bioactive Secondary Metabolites ◽  
Endophytic Microorganism

Fungal endophytes are a significant reservoir of novel bioactive secondary metabolites. Present communication describes isolation and structure determination of isochromenone, from endophytic microorganism <em>Aspergillus</em> <em>fumigatus</em> hosted in <em>Bacopa</em> <em>monnieri</em> plant. Further, its biological evaluation revealed it as antioxidant and antitubercular. The methanol extract of <em>A</em>. <em>fumigatus</em> inhibits the growth of the virulent strain of <em>Mycobacterium</em> <em>tuberculosis</em> H37RV with minimum inhibitory concentration 500 μg/mL. This is the first report of isolation of isochromenone from <em>A. fumigatus.</em>

scholarly journals PROFIL KANDUNGAN KIMIA DAN AKTIVITAS ANTIBAKTERI EKSTRAK METANOL DAUN BAMBAN (Donax canniformis (G. Forst.) K. Schum.) TERHADAP Staphylococcus aureus

2015 ◽  
Vol 1 (2) ◽  
pp. 141-148
Author(s):  
Hidayatullah Hidayatullah ◽  
Syariful Anam ◽  
Muhamad Rinaldhi Tandah
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Phenolic Compounds ◽  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Methanol Extract ◽  
Minimum Bactericidal Concentration ◽  
Dilution Method ◽  
The Family

Bamban (Donax canniformis (G. Forst.) K. Schum.) is one of the family Marantaceae plant that has many uses such as traditional medicine. Methanol extract of bamban leaves contains phenolic, tannins and saponins compounds. The purpose of this research is to determine the class of compounds that has antibacterial activity against Staphylococcus aureus and determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methanol extract of bamban leaves. This extract was prepared using maceration method with methanol solvent. Determination the class of compounds was initiated by bioautografi test in order to determine spots which has have antibacterial activity. Subsequently, the spot were identified the class of compound using reagent spray FeCl3 and H2SO4 10%. The determination of MIC and MBC using dilution method. Research showed there are three compounds that had antibacterial activity. These compounds were predicted as spot I and spot II which were phenolic compounds and spot III as a saponin compound. MIC and MBC value of the methanol extract of leaves bamban leaves 8% and 13%, respectively.

scholarly journals Screening of antimicrobial activity of essential oil and methanol extract of Satureja hortensis on foodborne bacteria and fungi

2008 ◽  
Vol 25 (No. 2) ◽  
pp. 81-89 ◽  
Author(s):  
A. Adiguzel ◽  
H. Ozer ◽  
H. Kilic ◽  
B. Cetin
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Composition ◽  
Minimum Inhibitory Concentration ◽  
Essential Oil ◽  
Inhibitory Concentration ◽  
Methanol Extract ◽  
Antimicrobial Activities ◽  
Satureja Hortensis ◽  
Bacteria And Fungi

The present work reports the <i>in vitro</i> antimicrobial activities of the essential oil and methanol extract from <i>Satureja hortensis</i> as well as the content of its essential oil. The chemical composition of hydrodistilled essential oil of Satureja hortensis was analysed by means of GC-MS. Thirty constituents were identified. The main constituents of the oil were thymol (40.54%), &gamma;-terpinene (18.56%), carvacrol (13.98%), and <i>p</i>-cymene (8.97). The essential oil of <i>Satureja hortensis</i> exhibited the activity against 25 bacteria, 8 fungi, and a yeast, <i>C. albicans</i>; exerting the Minimum Inhibitory Concentration values (MIC) ranging from 15.62 to 250 &micro;l/ml. Similarly, methanol extract of the plant also showed antimicrobial activity.

Determination of the minimum inhibitory concentration of four medicaments used as intracanal medication

2007 ◽  
Vol 33 (3) ◽  
pp. 107-111 ◽  
Author(s):  
Raul C. Pallotta ◽  
Mariangela S. Ribeiro ◽  
Manoel E. De Lima Machado
Keyword(s):  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration

A microfluidic microbial culture device for rapid determination of the minimum inhibitory concentration of antibiotics

The Analyst ◽  
2013 ◽  
Vol 138 (4) ◽  
pp. 1000 ◽  
Author(s):  
Rika Takagi ◽  
Junji Fukuda ◽  
Keiji Nagata ◽  
Yutaka Yawata ◽  
Nobuhiko Nomura ◽  
...  
Keyword(s):  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Rapid Determination ◽  
Microbial Culture
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