scholarly journals COVID-19: the difference between the nose and the lung

2021 ◽  
Vol 91 (2) ◽  
Author(s):  
Matteo Gelardi ◽  
Mario Notargiacomo ◽  
Eleonora Maria Consiglia Trecca ◽  
Michele Cassano ◽  
Giorgio Ciprandi
Keyword(s):  
Respiratory Syncytial Virus ◽  
Epstein Barr Virus ◽  
Respiratory Infections ◽  
Human Respiratory Syncytial Virus ◽  
Pathological Features ◽  
Barr Virus ◽  
Epstein Barr ◽  
The Difference ◽  
Syncytial Virus

To the Editor An elegant study reported dysmorphic cells and syncytia in the deceased's lungs for COVID-19. The authors reasonably considered that most of these syncytia-forming cells were pneumocytes, as identified by specific biomarkers. However, cellular dysmorphism and syncytia are pathological features common in other respiratory infections caused by different viruses, including the human respiratory syncytial virus (HRSV) and Epstein-Barr virus (EBV), as correctly documented... 

scholarly journals Viral placentitis: morphological features and verification possibilities

2018 ◽  
Vol 10 (4) ◽  
pp. 24-29 ◽  
Author(s):  
A. V. Kolobov ◽  
V. E. Karev
Keyword(s):  
Human Immunodeficiency Virus ◽  
Respiratory Syncytial Virus ◽  
Herpes Simplex ◽  
Epstein Barr Virus ◽  
Morphological Features ◽  
Barr Virus ◽  
Immunodeficiency Virus ◽  
Epstein Barr ◽  
Syncytial Virus ◽  
Simplex Virus

This article describes the results of own observations of viral placentitis caused by parvovirus, human immunodeficiency virus, respiratory syncytial virus and Herpesviridae family viruses – herpes simplex virus types 1 and 2, cytomegalovirus and Epstein–Barr virus), describing the morphological features of typical changes and immunohistochemical verification their etiology.

scholarly journals Mitoxantrone Shows In Vitro, but Not In Vivo Antiviral Activity against Human Respiratory Syncytial Virus

Biomedicines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1176
Author(s):  
Patricia G. de la Sota ◽  
Elena Lorente ◽  
Laura Notario ◽  
Carmen Mir ◽  
Oscar Zaragoza ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Infections ◽  
The Elderly ◽  
Human Respiratory Syncytial Virus ◽  
Mice Model ◽  
Drug Candidates ◽  
Antiviral Activities ◽  
Syncytial Virus

Human respiratory syncytial virus (HRSV) is the most common cause of severe respiratory infections in infants and young children, often leading to hospitalization. In addition, this virus poses a serious health risk in immunocompromised individuals and the elderly. HRSV is also a major nosocomial hazard in healthcare service units for patients of all ages. Therefore, the development of antiviral treatments against HRSV is a global health priority. In this study, mitoxantrone, a synthetic anthraquinone with previously reported in vitro antiprotozoal and antiviral activities, inhibits HRSV replication in vitro, but not in vivo in a mice model. These results have implications for preclinical studies of some drug candidates.

scholarly journals Nasal or throat sampling is adequate for the detection of the human respiratory syncytial virus in children with acute respiratory infections

2019 ◽  
Vol 91 (9) ◽  
pp. 1602-1607 ◽  
Author(s):  
Van Hoan Nguyen ◽  
Fiona M Russell ◽  
David AB Dance ◽  
Keoudomphone Vilivong ◽  
Souphatsone Phommachan ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Infections ◽  
Human Respiratory Syncytial Virus ◽  
Acute Respiratory Infections ◽  
Syncytial Virus

scholarly journals Epidemiology of Epstein-Barr virus in Malaysia

1970 ◽  
Vol 25 (2) ◽  
pp. 82-87 ◽  
Author(s):  
MR Norzuriza ◽  
W Kon Ken ◽  
M Mohammad ◽  
I Isahak ◽  
MM Rahman
Keyword(s):  
Enzyme Immunoassay ◽  
Epstein Barr Virus ◽  
Age Groups ◽  
Epidemiological Investigation ◽  
Barr Virus ◽  
Igm Antibodies ◽  
Significant Difference ◽  
Specific Igg ◽  
Epstein Barr ◽  
The Difference

An epidemiological investigation was carried out on patients reported to Hospital University Kebangsaan Malaysia (HUKM) suspected to be carriers of Epstein-Barr virus from July 2005 to June 2006. A total of 402 patients' sera were analyzed by Enzyme Immunoassay with Kit Enzygnost® by automated BEP® 2000 instrument. Of these 91.3% were found to carry Epstein-Barr virus (EBV) antibodies. Among these, 90.4%of male and 92.2% of female patients were positive: the difference was not significant. Considering community, 91.9% of Malay, 91.9% of Chinese, 75% of Indian and 93.3% of others were positive: the differences were not significant. Among the age groups, 77.5% of 0-20 year-olds, 98.6% of 21-40 year-olds, 96% of 41-60 year-olds and 100% of those above 60 years of age were positive: these differences were significant (p<0.005). No significant difference in the prevalence of EBV antibodies existed between the months of sampling. In the present study, EBV-specific IgG and IgM antibodies were determined. The proportion of samples positive to IgM was much less than those positive to IgG. DOI: 10.3329/bvet.v25i2.4622 Bangl. vet. 2008. Vol. 25, No. 2, 82-87

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