scholarly journals Fecondazione artificiale e crioconservazione degli embrioni

2006 ◽  
Vol 55 (1) ◽  
Author(s):  
Z. Serebrovska ◽  
M.L. Di Pietro ◽  
A. Bompiani

Nel ricorso alle tecniche di fecondazione artificiale extracorporea, la produzione di un numero elevato di embrioni e la crioconservazione dell’“eccedenza” è divenuta oramai una prassi. A prescindere dalle discutibili soluzioni adottate nei confronti degli embrioni “in eccedenza” per i quali non vi è più un progetto parentale, le stesse procedure di crioconservazione possono ridurre in modo drammatico le possibilità di sopravvivenza degli embrioni e rappresentare, quindi, un rischio per la vita dell’essere umano. Questa rassegna desidera esporre quanto si conosce, allo stato attuale, sul “rischio” per l’embrione crioconservato e documentarne l’entità attraverso le valutazioni statistiche offerte dai singoli autori. A tal fine vengono riportate: le principali metodiche; i limiti delle procedure di crioconservazione; la fase di sviluppo in cui la crioconservazione viene eseguita; i criteri utilizzati per valutare la qualità degli embrioni dopo lo scongelamento; i dati sulla sopravvivenza degli embrioni, sulle gravidanze e sulle nascite in alcuni centri di fecondazione artificiale. ---------- Production and cryopreservation of spare embryos has already become a routine in the practice of extra-corporal artificial fertilization techniques. Leaving out of considerations ethical problems of the questionable solutions which were taken regarding the “orphan” surplus embryos, who’s parents have no any more projects for pregnancy, it is necessary to underline that cryopreservation itself may dramatically decrease survival rate of embryos, which means create vital risk for human being. In the present review we attend to determine the eventual risks for embryo undergone cryopreservation examining the recent statistical data, published by different groups of authors. For this purpose we describe principal methods and critical points of cryopreservation, age of embryos in which cryopreservation occurs, criterions of evaluation of the quality of embryos after thawing, survival rate, pregnancy rate and life birth rate after cryopreservation in different centers in the world.

2000 ◽  
Vol 14 (8) ◽  
pp. 693-699 ◽  
Author(s):  
J Rodés ◽  
M Navasa

To date, more than 50,000 liver transplantations have been performed around the world; the survival rate five years after transplantation ranges from 60% to 65%. One of the fundamental objectives for liver transplantation teams is to achieve the best possible quality of life (QOL) for the patients. A concise analysis of the methodology used (15 questionnaires) to measure QOL of patients with liver transplants is described. The authors suggest that now is the time to establish a database so that a validated instrument will be available to compare QOL results from all the liver transplantation programs. Liver transplantation is believed to improve QOL, although there are several problems with some of the papers published on this subject. Some studies are retrospective, whereas in others, patients in bad physical conditions are excluded from the study; in quite a few prospective studies, deaths are not included in the data analysis. Finally, the authors provide a brief, concise analysis of late complications and of recurrence of the disease after liver transplantation, which influence QOL.


Author(s):  
А. Черняев ◽  
A. Chernyaev ◽  
Г. Кленов ◽  
G. Klenov2 ◽  
Андрей Бушманов ◽  
...  

Purpose: To make an analysis (including statistical data) of accelerator equipment for proton therapy (PT) in Russia and the world; to identify the main trends and directions of development in this area. Material and methods: Currently, proton therapy is developing rapidly in the world. Every year new proton centers are built. The number of commercial companies and research institutes, that are included in this high-tech sector, grows every year. Physicists and doctors together actively develop and introduce new ideas and technologies that are able to increase the efficiency and quality of proton therapy and also make it less costly. This review is an analysis of both publications in refereed publications, and reports made at relevant conferences and seminars. In addition, the data presented in the review are based on the information from the companies-manufacturers of equipment for proton therapy, which is open or provided for non-commercial use, with an indication of the sources. Results: In recent years, the main trends in the development of accelerators for proton therapy are: reducing the size and weight of machines, using of active pencil scanning as a standard method of dose delivering, reducing the time spent by patients in treatment rooms, using modulated radiation intensity in proton therapy. There is a transition from the construction of multi-cabin PT centers with an annual number of patients about 1000 people (due to their high cost and need to have an infrastructure for such big number of patients), to the creation of small-sized single-cabin complexes with an annual flow of several hundred people. Conclusion: Despite proton therapy has a good promotion and popularization activities, it is still an inaccessible method for most cancer patients with the exception of the United States, Japan and Europe. The lack of PT centers, the price per course of treatment, the lack of specialists in this area, and the attitude of most clinicians to PT as an experimental method of treatment is acute. In Russia, proton therapy does not receive enough support, despite the enormous potential and extensive experience that has been used for half a century of using PT. The last open proton center is private, and the only local manufacturer of equipment for PT exists only thanks to foreign contracts. Nevertheless, research and development continues. Moreover, the development is equal to the level of leading countries.


2019 ◽  
Vol 10 (4) ◽  
pp. 34-44
Author(s):  
V. Kh. Gilmanov
Keyword(s):  

In this article, I consider the philosophy of the Book in the context of reflections on her­meneutics in the works of the 18th-century Königsbergian thinker Johann Georg Hamann. Hamann’s bibliocentric hermeneutics treats the ‘philosophy of the Book’ as the question as to whether the experience of truth as such is possible. In the light of his hermeneutics, the fate of ontology is a function of the quality of reading since its dialogical nature directly determines a person’s special hermeneutic responsibility towards all that exists. In being the Book of Life, all that exists communicates with the human being as if it were the Book. It does so within the complex dialectics of objectivation in the epistemological linguisticality of a prophet, a scien­tist, or a poet and, through them, reaches out to countless generations of the Reader, who is voluntarily or involuntarily involved in the existential fate of the ontological dialogue. The ‘death of the Book’, or the transformation of the Book into a simulacrum, may confirm the diagnosis given by many modern philosophers: the world of culture is turning into an autoch­thonous flicker of hybrid quotations ruins.


1970 ◽  
pp. 67-75
Author(s):  
Sławomir Futyma

Sensory experience leads to the initiation of a complex process of thinking about the world. The result of this process are the images of what surrounds us. We definethis action as education. Because looking at the world from the perspective of sensual experience is the potential ability of every human being (Hannah Arendt), education becomes a tool enabling the simulation of the existing world and the one that may appear in the future. About who we are and where we are, who we will decide, the quality of the senses. The quality of the senses translates into the value of the cognitive process. The consequence of the quality of the cognitive process is the collection of information and knowledge. This sensual logic inscribes the action that classifiesus people according to predisposition or ava-ilable information that results from the quality of sensual functioning. As Leonardo da Vinci saw it: “Experience, the intermediary between creative nature and the human race, teaches what nature uses among mortals, that before the necessity of necessity one cannot act differently than reason, his teaching works.”


2010 ◽  
Vol 17 (4) ◽  
pp. 613-637 ◽  

The progress of countries is measured by their success in keeping hold of their culture and heritage, and I think Egypt is one of the very few countries in the world maintaining her cultural patrimony. We have been able, through a great effort led by Farouk Hosni, the Minister of Culture, to preserve and offer this heritage to the world as evidence of the magnificence of this great country, on whose land the most important civilization in existence was born. This civilization is in the heart of every human being on earth. The French newspaper, Le Figaro, published an article some time ago commending the quality of restoration and maintenance of Egyptian monuments, as well as new discoveries made by an Egyptian team.


2020 ◽  
Author(s):  
Leonardo Juan Ramirez Lopez ◽  
Nicolas Beltrán Álvarez

<p>The impact of COVID-19 has challenged science in its quest to control and mitigate it through a new vaccine. This is why the world's research centers and laboratories are in serious competition over time to offer humanity an effective vaccine that prevents the spread of this virus. From a technological point of view, the challenge is to manage the distribution of this next vaccine, from its generation anywhere in the world, to the site of application to the population. The research results approximate the solution to the design of a secure Blockchain-based supply chain surveillance design, to control the variables and critical points of the next distribution of vaccines worldwide. The expected impact of the application of this new design will be the confidence of the population in the quality of the vaccine, in the generating laboratory, and it supplies.</p>


2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Kumar Neeraj Sachdev

An attempt is made in the paper to analyze the nature of virtue of ecological sensitivity to argue for its relevance and need in the business world. Ecological sensitivity is a virtue or quality of a human being to relate himself to the environment in a protective spirit of oneness. It is not a virtue by extension from human to environment like compassion or empathy but a virtue of independent normative standing since it is argued to be equal to other personal and inter-personal virtues in the pool of virtues to live a good human life. It is further argued that since ethics is a study of values and virtues to live a good human life and business companies are a great source to sustain and improve upon the state of mankind in the world and the condition of planet earth itself, it makes sense to emphasize the need to include ecological sensitivity as a virtue in the conduct of business professionals. It also attempts to understand how the business professionals ought to interpret ecological sensitivity in and around their surroundings on a daily basis.


2020 ◽  
pp. 119-128
Author(s):  
Oleksii V. Lyulyov ◽  
Bogdan A. Moskalenko

Investment attractiveness of a country, and approaches to its evaluation have been thoroughly debated over few last decades. Initially, the key question concerned the reasons as to why large number of resource holders (financial funds, technologies, management systems etc.) would locate their assets, especially research and development projects, in other countries rather than remaining in their home economies. Increasing the quantity and quality of contacts with developed countries within investment process is crucially important for the development of Ukrainian economy. As follows from that point, the authors have identified features of approaches to investment attractiveness evaluation on a macroeconomic level analyzing latest works of scientists and researchers around the world. It is believed, that the most valuable type of investments for future GDP growth is funds from multinational corporations: they bring not only money, but technologies, and decision how make new businesses profitable. Thus, the fundamental consideration for countries competing for investments is the influencing and improvement of such factors through effective investment incentives policies. Within this work, we researched recent studies of investment attractiveness evaluation around the world, and assumed key points for improving and applying those approaches in Ukrainian economy. Within literature analysis the authors structured approaches to the evaluation based on the methods and subjects those approaches used. The most common methods are related to econometric analysis of statistical data that is collected and published by international institutions and rating agencies. Current analysis shows a tangible dependence between country investment attractiveness and the dynamics of FDI inflows. This dependence is not always straightforward, which is explained by influence of many other determinants within decision-making process. The authors suggest that involving independent experts from respective sectors of the economy could help to optimize the results of statistical data analysis. The expert survey provides the necessary correction coefficients which are to increase the accuracy and relevance of the investment attractiveness evaluation. The authors proposed a generalized approach to assessing the country investment attractiveness, taking into account international experience and features of the Ukrainian economy. Key words: investments, country investment attractiveness, foreign direct investment, investment attractiveness evaluation.


2020 ◽  
Vol 74 ◽  
pp. 04015
Author(s):  
Hana Maťová ◽  
Miroslava Triznová ◽  
Vladislav Kaputa ◽  
Mikuláš Šupín ◽  
Eva Drličková ◽  
...  

The article focuses on CSR 2.0 concept (Corporate Sustainability and Responsibility) in context with concept of a circular economy and responsible consumer. The main goal of CSR 2.0 is an improvement of the quality of life for all people in the world. This concept perceives consumers as global citizens. The basic principles of CSR 2.0 are Creativity (C), Scalability (S), Responsiveness (R), Glocality (2) and Circularity (0). The companies which implement CSR 2.0 can bring innovative solutions to most pressing social, environmental and ethical problems and challenges in the world. Responsible and conscious consumers can engage in the process of implementing CSR 2.0 by their willingness to collaborate and participate in the marketplace and corporate world. The aim of this paper is to look at the consumer from the “Glocality and Circularity perspective” according to the basic principles of CSR 2.0 in the condition of the Slovak Republic. To fulfil this aim, we conducted a survey of 1061 Slovak inhabitants. The results show the profile of our respondents according to their local actions (environmental actions, buying ethical products etc.) and their profile/activities regarding their participation on circularity (e.g. recycling, re-using, sharing etc.).


2017 ◽  
Vol 6 (1) ◽  
pp. 42
Author(s):  
Besse Darmawati

A good literary works are able to give positive values to human being. This research aims to describe the elements, meaning, and cultural values in the poems that contain positive values for human life. The researcher applies qualitative method through objective and intuitive approaches. The meaning and cultural values of the poems are intuitively gained from the result of the analysis objectively. The data are “Kata Cinta Usia 51”, “Jabatan Yang Hilang” and “Kita Adalah Pemilik Sah Republik Ini.” Objectively, these poems have the themes of belief in worldly life, the excessive mistaken, and the resurrection of life. Intuitively, the meaning of these three poems makes people aware that life is only temporary, so they cannot escape from gratitude, must not feel despair in facing hardships, are not mistaken by the beauty of the world, and strive to achieve a good quality of life. The cultural values of these poems are gratitude, fortitude, faithful, patience, bravery, firmness, and responsibility. These reflect the characters and identities of young generations as their identities, so they are different from other nations, in order to awaken their identity as a dignified Indonesian nation.   ABSTRAK Karya sastra yang baik mampu memberi nilai positif terhadap manusia. Penelitian ini bertujuan untuk mendeskripsikan unsur, makna, dan nilai budaya dalam puisi yang bernilai positif bagi kehidupan manusia. Penulis menerapkan metode penelitian deskriptif kualitatif melalui pendekatan objektif dan intuitif. Makna dan nilai budaya dalam puisi secara intuitif diperoleh dari hasil analisis secara objektif. Data adalah puisi “Kata Cinta Usia 51,” “Jabatan Yang Hilang,” dan “Kita Adalah Pemilik Sah Republik Ini.” Secara objektif, puisi tersebut bertemakan keyakinan terhadap kehidupan duniawi, kekeliruan yang berlebihan, dan kebangkitan hidup. Secara intuitif, makna ketiga puisi tersebut menyadarkan manusia bahwa hidup hanya sementara sehingga tidak terlepas dari rasa syukur, jangan putus asa menghadapi cobaan, jangan keliru dengan keindahan dunia, dan berjuang mencapai kehidupan yang berkualitas. Adapun nilai budaya dari puisi tersebut adalah kesyukuran, ketabahan, keyakinan, kesabaran, keberanian, keteguhan, dan bertanggung jawab. Hal demikian mencerminkan karakter dan identitas anak bangsa sebagai jati diri mereka, sehingga berbeda dengan bangsa lain, dalam rangka menggungah identitas sebagai bangsa Indonesia yang bermartabat.


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