scholarly journals HYPOSPADIAS: LONG TERM FOLLOW-UP IN A SINGLE CENTER

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
F. Molinaro ◽  
R. Angotti ◽  
E. Bindi ◽  
M. Sica ◽  
M. Aglianò ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Intraoperative Complications ◽  
Surgical Techniques ◽  
Clinical Manifestations ◽  
Disorders Of Sex Development ◽  
Complex Disorders ◽  
Aesthetic Appearance ◽  
Long Term Follow Up

<em>Introduction</em>: Hypospadias is one of the most common birth defects that affect the male urogenital tract. It can present as isolated anomaly, but sometimes can arise in the context of complex disorders of sex development (DSD). These malformations are characterized by a great variety of clinical manifestations and compromise the aesthetic appearance, but also functional and psychological impact that the malformation can determine the patient. <br /><em>Materials and Methods</em>: We conducted a retrospective study of patients undergoing surgery for hypospadias from March 2000 to January 2015. The data was extrapolated from a prospective database. It was considered for each patient: demographics; type of hypospadias; surgical technique; average age for surgery; intraoperative and postoperative complications (early and late). Duckett’s classification was used. <br /><em>Results</em>: 343 urethroplasties were performed. 320 (93%) were primary urethroplasties and 23 (7%) reoperations in patients who had performed many other surgical procedures. 7 patients with megameatus were excluded. The hypospadias have been ranked according to Duckett’s classification, 35 patients had associated diseases. In total were performed: 186 (55%) Snodgrass, 71(21%) Duckett,10 (3%) augmented Duckett, 42 (13%) Magpi, 16 (5%) Duplay, 1 (0,3%) Bracka, 1 (0,3%) was a Bianchi’technique and 5 (1,4%) were Standoli. In 4 patients (1%) were used mixed technique. There were no intraoperative complications. The mean age at surgery was 15 months (range 12-22 months). Postoperative complications were 12%. Long term follow up was done with uroflussimetrie at 3 and 6 months in those who had reached the continence and possible urethral calibrations in those who had submitted a stenosis in post-op.<br /><em>Conclusions</em>: The improvement of surgical techniques, the use of optical amplification tools, the use of suture material (PDS) and the experience gained in recent years have enabled us to optimized the results. Though aware of the potential and actual complications that this type of microsurgical correction can lead to the results we have obtained are comparable to those of major international series and can be considered satisfactory, both from an aesthetic and functional.

Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications

2019 ◽  
Vol 57 (10) ◽  
pp. 998-1002 ◽  
Author(s):  
Paola Bonavolontà ◽  
Giovanni Dell'Aversana Orabona ◽  
Fabio Maglitto ◽  
Vincenzo Abbate ◽  
Umberto Committeri ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Long Term Follow Up

scholarly journals Clinical Manifestations and Long-Term Follow-Up in Pediatric Patients Living at Altitude With Isolated Pulmonary Artery of Ductal Origin

2012 ◽  
Vol 33 (5) ◽  
pp. 775-781 ◽  
Author(s):  
Shinichi Takatsuki ◽  
Jeffrey R. Darst ◽  
Bibhuti B. Das ◽  
Thomas E. Fagan ◽  
Robert Wolfe ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Pediatric Patients ◽  
Clinical Manifestations ◽  
Long Term Follow Up ◽  
Isolated Pulmonary Artery

scholarly journals SAT0274 DESCRIPTIVE ANALYSIS OF FLARES DURING THE LONG-TERM FOLLOW-UP OF PATIENTS WITH BEHÇET’S DISEASE INCLUDED IN REGEB COHORT

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1081.2-1081
Author(s):  
M. Rodríguez Carballeira ◽  
R. Solans ◽  
R. Ríos Fernández ◽  
B. Escalante ◽  
B. Maure ◽  
...  
Keyword(s):  
Behcet’S Disease ◽  
Biological Therapy ◽  
Behçet's Disease ◽  
Clinical Manifestations ◽  
Refractory Disease ◽  
Behcet's Disease ◽  
Long Term Follow Up ◽  
Genital Ulcers

Background:Objectives:To describe the clinical manifestations and treatment of flares during follow-up in patients with Behçet’s disease (BD) included in the REGEB cohort over the last decade.Methods:The Spanish Registry of BD or REGEB (REGistrode la Enfermedad de Behçet as Spanish nomenclature) Project Group was created by the Spanish Internal Medicine Society in 2009 with the aim of compiling a large cohort of Spanish patients with this rare disorder. By July 2012, REGEB has collected 635 BD patients with a multicentre, longitudinal and consecutive design. Diagnosis of BD was performed on the basis of the International Study Group criteria for BD. Since inclusion in the registry, patients have been followed prospectively and new flares have been recorded, defined as those clinical manifestations which have required initiation or modification of immunosuppressive treatment, or prednisone dose at or higher than 10mg/d of prednisone during more than 1 month.Results:A prospective follow-up of 326 patients included in the registry has been analysed. There are 182 women (56%) and their average age (SD) at the time of diagnosis was 33 (13) years. The majority of them were Caucasian (91%). The median follow-up time from BD diagnosis was 180 months, and the prospective follow-up period from the inclusion in the registry was 80 months. The cumulative clinical manifestations until the initial registration were oral ulcers in 100% of patients, genital ulcers in 221 (68%), arthritis in 147 (45%), erythema nodosum in 96 (29%), fever in 82 (25%), thrombosis in 74 (23%), anterior uveitis in 76 (23%), retinal vasculitis in 46 (14%), posterior uveitis in 35 (11%), aseptic meningitis in 32 (10%), and other neurological manifestations in 15 (5%) patients. One hundred and fifty-six (48%) patients received immunosuppressants and 47 (14%) biological therapy.During follow up (period from the inclusion in the REGEB to the last visit) 68 (23%) patients presented at least a severe outbreak. The median time from the BD diagnosis to the first flare were 170 months. The main clinical manifestations were oral-genital ulcers in 43 (63%) patients, uveitis in 31 (45%), arthritis in 13 (19%), neurological in 16 (24%), vascular in 10 (15%), and gastrointestinal in 3 (4%) patients. Immunosuppressants were used in 37 (54%) patients and biological therapy in 14 (21%). Biological therapy was mostly used due to refractory disease, the majority of cases because ocular manifestations. There were no differences in terms of age, sex, race and previous clinical manifestations between patients who suffered from flares and those who did not. Flares were more frequent in patients who have received previous immunosuppressive or biological treatment (35% vs 13% and 48% vs 19%, respectively) (p<0.001 in both cases), probably reflecting a more severe disease.Conclusion:The long-term follow-up of BD patients from REGEB cohort showed that 10 years after diagnosis, a fifth of them may continue to present severe flares requiring systemic treatment. The use of biological therapy increased over time and their main indication was refractory disease.Disclosure of Interests:Mónica Rodríguez Carballeira: None declared, Roser Solans: None declared, Raquel Ríos Fernández: None declared, Begoña Escalante: None declared, Brenda Maure: None declared, Alejandra Fernández: None declared, Robert Hurtado: None declared, Rafael Boldova: None declared, Gerard Espinosa Speakers bureau: Glaxo-Smith-Kline, Janssen, Boehringer, Rovi

scholarly journals Long Term Follow-up of Laser Myopia Surgery

2020 ◽  
Author(s):  
Gracia Castro-Luna ◽  
Hazem Alaskar ◽  
Antonio Pérez-Rueda ◽  
Diana Jimenez-Rodriguez
Keyword(s):  
Randomized Study ◽  
Surgical Techniques ◽  
Spherical Equivalent ◽  
Safety Index ◽  
Long Term Follow Up ◽  
Efficacy Index ◽  
One Year ◽  
Myopic Astigmatism

Refractive surgery is an increasingly popular procedure to decrease spectacle or contact lens dependency. The two most commonly used surgical techniques to correct myopia is Photorefractive keratectomy (PRK) and Femtosecond- Lasik (FS-LASIK)There are few publications that gathers such a long term follow up of both surgical techniques (2) Methods It has been performed a retrospective non-randomized study 509 PRK eyes and 310 FS-LASIK surgeries were followed for 10 years for the treatment of myopia and compound myopic astigmatism. Patients were followed up three months, one year, 2 years, 5 and 10 years. The safety index of both procedures was defined as a quotient between the postoperative BCVA (Best Corrected Visual Acuity) and the preoperative BCVA. The predictability is calculated as difference between the expected spherical equivalent and the achieved spherical equivalent. The efficacy index was calculated as a quotient between postoperative UCVA divided by the preoperative BCVA (3) Results. The results were: a safety index higher than 100% (109%) and an efficacy index of 82.4% after 10 years of PRK surgery in both groups. FS-LASIK was the safest surgery after 10 years and the most efficacy technique although in this case there were no statistically significant differences (4) Conclusions. All these data demonstrated better indexes for FS-LASIK

scholarly journals Shall we treat patients with benign epileptiform discharges of childhood without epileptic seizures?

2019 ◽  
Vol 14 (1) ◽  
pp. 7-13
Author(s):  
N. A. Ermolenko ◽  
I. S. Bakhtin ◽  
I. A. Buchneva
Keyword(s):  
Focal Epilepsy ◽  
Clinical Manifestations ◽  
Epileptic Seizures ◽  
Healthy Children ◽  
Epileptiform Discharges ◽  
First Choice ◽  
Long Term Follow Up ◽  
Potential Risks

Benign epileptiform discharges of childhood are age-dependent electroencephalogram patterns associated with idiopathic benign focal epilepsy. Multiple studies have demonstrated that focal epileptiform discharges can be registered in patients without any clinical manifestations of epilepsy. Long-term follow-up of clinically healthy children with benign epileptiform discharges of childhood on electroencephalogram demonstrated that 14 % of them developed epileptic seizures with age and 50 % developed various cognitive and behavioral disorders. The question of whether or not to treat such patients (with benign epileptiform discharges of childhood on electroencephalogram but without epileptic seizure) is still being widely discussed. Individual decision making with the consideration of potential risks and benefits for a patient is preferable in this case. Valproic acid is the drug of first choice in these patients.

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