scholarly journals Adult onset Still’s disease presenting as fever of unknown origin: a case report with review of literature

2017 ◽  
Vol 11 ◽  
Author(s):  
Harpreet Singh ◽  
Deepak Jain ◽  
Saroj Dhankhar ◽  
Rekha Mathur
Keyword(s):  
Joint Pain ◽  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Rheumatologic Diseases ◽  
Systemic Inflammatory Disease ◽  
Adult Onset Still's Disease

Adult onset Still’s disease (AOSD) is a systemic inflammatory disease with exact etiology and pathogenesis yet to be discovered. AOSD, being an important cause of fever of unknown origin, is diagnosed after ruling out infections, malignancy and other rheumatologic diseases. It may present with fever without typical rash although typical triad is of fever, joint pain and rash. A 35-year old previously healthy man was referred to our hospital with 6 months of fever, joint pain and weight loss. Examination and investigations revealed anaemia, leukocytosis (predominant neutrophilia), lymphadenopathy, hepatomegaly, arthritis and evidence of interstitial lung disease with raised serum ferritin levels. The hematological disorders, infections and other rheumatologic diseases were excluded. The diagnosis of adult onset Still’s disease can be very difficult as there are no specific tests and diagnosis is based on symptom complex. AOSD presenting as fever of unknown origin could be a challenge for the physician to diagnose and manage timely.

scholarly journals Effect of Ultrasound Therapy on the Adult-Onset Still’s Disease: A Case Study

2020 ◽  
Vol 10 (1) ◽  
pp. 49-54
Author(s):  
Manal Yooussef ◽  
Keyword(s):  
Short Form ◽  
Unknown Origin ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Timed Up And Go ◽  
Still's Disease ◽  
Muscle Testing ◽  
Systemic Inflammatory Disease ◽  
Adult Onset Still's Disease

Adult Onset Still’s Disease (AOSD) is a rare systemic inflammatory disease of unrecognized etiology and pathogenesis that presents in 5% to 10% of patients as Fever of Unknown Origin (FUO) accompanied by systemic manifestations. We reported a compelling case of a 39-year-old African male who presented with a one-month duration FUO along with skin rash, sore throat, and arthralgia. After an extensive workup, potential differential diagnoses were ruled out, and the patient was diagnosed with AOSD based on the Yamaguchi criteria. After the application of Ultrasound (US) and exercises on both ankles as well as left knee, left elbow, and left wrist, there was an improvement of Visual Analogue Scale by 66.6%, Five Repetition Sit to Stand Test (FRSTS) improved 50%, Timed Up and Go (TUG) test improved 87.5%, and there was also an improvement in the 36-Item Short Form Survey (SF-36), and muscle testing. This result was due to the anti-inflammatory effect of the US, leading to decrease pain and improve function in the individuals.

scholarly journals ADULT ONSET STILL'S DISEASE AS FEVER OF UNKNOWN ORIGIN - A CASE REPORT

2021 ◽  
Author(s):  
Jéssica Tomps Corrêa ◽  
Gabriela Ferreira Rocha ◽  
Vinícius Shinoda Pereira ◽  
Victor Gomes Rocha ◽  
Erickson Gomes Gutierrez ◽  
...  
Keyword(s):  
Case Report ◽  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

scholarly journals Adult-Onset Still's Disease and Cardiac Tamponade: A Rare Association

2015 ◽  
Vol 42 (3) ◽  
pp. 277-280 ◽  
Author(s):  
Pedro Carrilho-Ferreira ◽  
Doroteia Silva ◽  
Maria de Jesus Silva ◽  
Rui André ◽  
Manuel Gato Varela ◽  
...  
Keyword(s):  
Cardiac Tamponade ◽  
Conservative Therapy ◽  
Unknown Origin ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Invasive Approach ◽  
Still's Disease ◽  
Systemic Inflammatory Disease ◽  
Adult Onset Still's Disease

Adult-onset Still's disease is a rare disorder with potentially severe clinical features, including cardiac involvement. This systemic inflammatory disease of unknown origin should be considered in the differential diagnosis of pericarditis, with or without pericardial effusion. Cardiac tamponade is a very rare sequela that requires an invasive approach, such as percutaneous or surgical pericardial drainage, in addition to the usual conservative therapy. The authors describe a case of adult-onset Still's disease rendered more difficult by pericarditis and cardiac tamponade, and they briefly review the literature on this entity.

scholarly journals A complicated fever

2007 ◽  
Vol 1 (1) ◽  
pp. 31-37
Author(s):  
Paolo Ghiringhelli ◽  
Mariagrazia Aspesi
Keyword(s):  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Disease Evolution ◽  
Still's Disease ◽  
Symptom Complex ◽  
Inflammatory Drugs ◽  
Adult Onset Still's Disease

Fever of unknown origin is a common problem in medical practice and assemble a broad spectrum of diagnostic possibilities. We report a case of a 24-year-old woman with high-spiking fever. A diagnosis of adult-onset Still’s disease (AOSD) was made. This is a rare inflammatory disease with an unknown aetiology. The diagnosis of adult-onset Still’s disease can be very difficult. There are no specific tests and reliance is usually placed on a symptom complex and the well described typical rash seen in most patients. Thus, the diagnosis is made by exclusion and with the help of diagnostic criteria. The treatment of this disease has to limit the intensity of the symptoms, and this is usually obtained with NSAIDs (NonSteroidal Anti-Inflammatory Drugs), and to control the disease evolution, through the use of corticosteroid, methotrexate or ciclosphorine A. In the case here described treatment with corticosteroid met with a good response.

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