scholarly journals Obstructive sleep apnea and arterial hypertension

2016 ◽  
Vol 10 ◽  
Author(s):  
Claudio Pascale ◽  
Giuliano Pinna ◽  
Nathan Artom
Keyword(s):  
Heart Failure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cardiovascular Diseases ◽  
Arterial Hypertension ◽  
Medical Literature ◽  
Medical Knowledge ◽  
Obstructive Sleep ◽  
The Relationship

In recent years there is a growing interest regarding the relationship between obstructive sleep apnea (OSA) and cardiovascular diseases. Consequently, there is a large increase in medical literature of papers on the connections between OSA and hypertension, heart failure, arrhythmias and other cardiovascular diseases. In this work, authors review medical knowledge between OSA, arterial hypertension and cardiovascular diseases.

scholarly journals Obstructive Sleep Apnea in Heart Failure: Review of Prevalence, Treatment with Continuous Positive Airway Pressure, and Prognosis

2018 ◽  
Vol 45 (3) ◽  
pp. 151-161 ◽  
Author(s):  
Himad K. Khattak ◽  
Faisal Hayat ◽  
Salpy V. Pamboukian ◽  
Harvey S. Hahn ◽  
Brian P. Schwartz ◽  
...  
Keyword(s):  
Heart Failure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Preserved Ejection Fraction ◽  
Obstructive Sleep ◽  
Artery Disease ◽  
The Relationship

Obstructive sleep apnea is a sleep-related breathing disorder that has a major impact on cardiovascular function. It has been associated with hypertension, coronary artery disease, cardiac arrhythmias, sudden cardiac death, and heart failure. This review focuses on the relationship between obstructive sleep apnea and heart failure with either reduced or preserved ejection fraction. We discuss the pathophysiology of obstructive sleep apnea, as well as its prevalence, treatment outcomes with continuous positive airway pressure, and prognosis in these 2 distinct types of heart failure. We also identify areas in which further work is needed to improve our understanding of this association in heart failure patients.

scholarly journals Obstructive sleep apnea syndrome is a risk factor for arterial hypertension

2003 ◽  
Vol 9 (2) ◽  
pp. 37-41
Author(s):  
A. L. Kalinkin
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Cardiovascular Diseases ◽  
Arterial Hypertension ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Experimental Studies ◽  
Obstructive Sleep ◽  
Apnea Syndrome

The obstructive sleep apnea syndrome (OSAS) is a risk factor for cardiovascular diseases The results of epidemiological, observational, and experimental studies support the fact that OSAS is of considerable importance in the development of arterial hypertension via chronic sympathetic activation and sleep-induced neurohumoral changes OSAS is of prime importance in the development of refractory AH CPAP therapy not only eliminates sleep-induced obstructive respiratory impairments, but frequently lowers blood pressure in hypertensive patients, and improves the prognosis of cardiovascular diseases

scholarly journals The relationship of obstructive sleep apnea and cardiovascular diseases from the perspective of evidence-based medicine. Part 1

2020 ◽  
Vol 19 (3) ◽  
pp. 2405
Author(s):  
М. V. Agaltsov ◽  
O. M. Drapkina
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cardiovascular Diseases ◽  
Sleep Disorders ◽  
Developed Countries ◽  
Obstructive Sleep ◽  
Number Of Patients ◽  
High Prevalence ◽  
Relationship Of ◽  
The Relationship

The results of prospective studies, meta-analyzes and systematic reviews on the associations of obstructive sleep apnea (OSA) with various cardiovascular diseases (CVD) were analyzed. Currently, the mechanisms related to high prevalence of breathing-related sleep disorders among population of economically developed countries are clear, and an increase in the number of OSA patients has been shown. The relationship between OSA and CVD has been widely confirmed in large cohort studies. The first review part discusses the relationship of hypertension (HTN) and various heart arrhythmias (atrial fibrillation (AF), bradyarrhythmias, premature ventricular contraction, sudden death during sleep) with breathing-related sleep disorders. These groups of cardiovascular disorders currently show the most proven relationship with sleep apnea. In addition to cross-sectional studies indicating the high prevalence of OSA in patients with HTN and AF, some observational studies indicate an increase in the number of patients with HTN and paroxysmal AF with history of untreated sleep apnea. An analysis of the current issues of OSA phenotypes (in particular, REM-related OSA in hypertensive patients) as the most unfavorable cardiovascular factors is carried out.

scholarly journals Obstructive Sleep Apnea, Oxidative Stress and Cardiovascular Disease: Lessons from Animal Studies

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Rio Dumitrascu ◽  
Joerg Heitmann ◽  
Werner Seeger ◽  
Norbert Weissmann ◽  
Richard Schulz
Keyword(s):  
Oxidative Stress ◽  
Heart Failure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Animal Models ◽  
Arterial Hypertension ◽  
Animal Studies ◽  
Treatment Options ◽  
Free Oxygen Radicals ◽  
Obstructive Sleep

Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular (CV) diseases such as arterial hypertension, heart failure, and stroke. Based on human research, sympathetic activation, inflammation, and oxidative stress are thought to play major roles in the pathophysiology of OSA-related CV diseases. Animal models of OSA have shown that endothelial dysfunction, vascular remodelling, and systemic and pulmonary arterial hypertension as well as heart failure can develop in response to chronic intermittent hypoxia (CIH). The available animal data are clearly in favour of oxidative stress playing a key role in the development of all of these CV manifestations of OSA. Presumably, the oxidative stress is due to an activation of NADPH oxidase and other free oxygen radicals producing enzymes within the CV system as evidenced by data from knockout mice and pharmacological interventions. It is hoped that animal models of OSA-related CV disease will continue to contribute to a deeper understanding of their underlying pathophysiology and will foster the way for the development of cardioprotective treatment options other than conventional CPAP therapy.

scholarly journals Environmental Factors as Modulators of the Relationship between Obstructive Sleep Apnea and Lesions in the Circulatory System

2020 ◽  
Vol 9 (3) ◽  
pp. 836
Author(s):  
Dominika Urbanik ◽  
Helena Martynowicz ◽  
Grzegorz Mazur ◽  
Rafał Poręba ◽  
Paweł Gać
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cardiovascular Diseases ◽  
Environmental Factors ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Developed Countries ◽  
Cerebral Stroke ◽  
Obstructive Sleep ◽  
The Relationship

Obstructive sleep apnea (OSA) is a growing social problem, particularly in well-developed countries. It has been demonstrated that obstructive sleep apnea is a significant risk factor for cardiovascular diseases, including arterial hypertension, ischemic heart disease, heart failure, rhythm/conduction disturbances, as well as cerebral stroke. The pathophysiology of these diseases is complex and multifactorial. We present the current state of research on behavioral and environmental factors that influence the relationship between OSA and cardiovascular changes. We discuss the relationship between obesity, alcohol, sedatives, environmental tobacco smoke, allergic diseases and environmental pollution on the one hand and OSA on the other. In this context, the environment should be considered as an important modulator of the relationship between OSA and cardiovascular diseases.

scholarly journals Continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea syndrome and arterial hypertension: expert opinion

2018 ◽  
Vol 15 (2) ◽  
pp. 77-78
Author(s):  
A Yu Litvin ◽  
E M Elfimova ◽  
I E Chazova
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Arterial Hypertension ◽  
Positive Airway Pressure ◽  
Sleep Apnea Syndrome ◽  
Cardiovascular Complications ◽  
Cpap Therapy ◽  
Obstructive Sleep ◽  
The Relationship

The combination of the obstructive sleep apnea (OSA) syndrome and arterial hypertension (AH) is a common problem affecting both the medical and social aspects of a patient's life. CPAP-therapy is the main treatment of sleep-discorded breathing. This paper focuses on up-to-date data on the relationship between OSA and AH and reviews studies evaluating the effect of CPAP-therapy on blood pressure, the risk of cardiovascular complications and the quality of life of patients.

scholarly journals Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

Diseases ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 88
Author(s):  
Amal K. Mitra ◽  
Azad R. Bhuiyan ◽  
Elizabeth A. Jones
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Heart Failure ◽  
Systematic Review ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cardiovascular Diseases ◽  
Oxygen Desaturation ◽  
Oxygen Desaturation Index ◽  
Obstructive Sleep

Obstructive sleep apnea (OSA) is a serious, potentially life-threatening condition. Epidemiologic studies show that sleep apnea increases cardiovascular diseases risk factors including hypertension, obesity, and diabetes mellitus. OSA is also responsible for serious illnesses such as congestive heart failure, stroke, arrhythmias, and bronchial asthma. The aim of this systematic review is to evaluate evidence for the association between OSA and cardiovascular disease morbidities and identify risk factors for the conditions. In a review of 34 studies conducted in 28 countries with a sample of 37,599 people, several comorbidities were identified in patients with severe OSA—these were: heart disease, stroke, kidney disease, asthma, COPD, acute heart failure, chronic heart failure, hyperlipidemia, thyroid disease, cerebral infarct or embolism, myocardial infarction, and psychological comorbidities including stress and depression. Important risk factors contributing to OSA included: age > 35 years; BMI ≥ 25 kg/m2; alcoholism; higher Epworth sleepiness scale (ESS); mean apnea duration; oxygen desaturation index (ODI); and nocturnal oxygen desaturation (NOD). Severe OSA (AHI ≥ 30) was significantly associated with excessive daytime sleepiness and oxygen desaturation index. The risk of OSA and associated disease morbidities can be reduced by controlling overweight/obesity, alcoholism, smoking, hypertension, diabetes mellitus, and hyperlipidemia.

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