scholarly journals Invasive aspergillosis in an immunocompetent patient with fever and a cardiac mass

2011 ◽  
Vol 3 (2) ◽  
Author(s):  
Matthew LaBarbera ◽  
Lester B. Jacobson
2011 ◽  
Vol 3 (2) ◽  
pp. 12 ◽  
Author(s):  
Matthew LaBarbera ◽  
Lester B. Jacobson

Invasive aspergillosis is an often fatal disease that usually occurs in immunocompromised patients. We report a case of invasive aspergillosis presenting as a febrile respiratory infection with a cardiac mass in an immunocompetent patient. Invasive aspergillosis should be considered in the differential diagnosis of an otherwise undiagnosed febrile respiratory illness, even in immunocompetent patients. Echocardiography should be peformed to evaluate for endocarditis in such cases. Prompt initiation of appropriate antifungal therapy is warranted, even before the diagnosis of invasive aspergillosis is confirmed.


IDCases ◽  
2021 ◽  
pp. e01232
Author(s):  
Grace D. Cullen ◽  
Tara M. Davidson ◽  
Zachary Yetmar ◽  
Bobbi S. Pritt ◽  
Daniel C. DeSimone

Cureus ◽  
2017 ◽  
Author(s):  
Manesh Kumar Gangwani ◽  
Muhammad Aziz ◽  
Siraj Munir ◽  
Syed Ahsan Ali

CHEST Journal ◽  
2019 ◽  
Vol 156 (4) ◽  
pp. A552
Author(s):  
Jenny Yang ◽  
Abdurrahman Husain ◽  
Jeremy Orr

2009 ◽  
Vol 124 (9) ◽  
pp. 1010-1013 ◽  
Author(s):  
M J Parsonage ◽  
N D Stafford ◽  
P Lillie ◽  
P J Moss ◽  
G Barlow ◽  
...  

AbstractBackground:Intravenous amphotericin or intravenous voriconazole, both followed by oral voriconazole, have previously been given to treat invasive aspergillosis of the skull base.Case report:Exclusively oral voriconazole was used in an immunocompetent patient with biopsy-proven, invasive aspergillosis. She had a large, erosive lesion extending from the central skull base to the right orbit and ethmoid sinus, and displacing the right internal carotid artery. After four months of oral treatment as an out-patient, a repeated computed tomography scan showed a fully treated infection with post-infectious changes only, and treatment was terminated. Two years later, there had been no recurrence.Conclusion:Substantial cost savings were made by using exclusively oral treatment, compared with the use of intravenous voriconazole or amphotericin, or a switch strategy.


2019 ◽  
Vol 27 (6) ◽  
pp. 370-373
Author(s):  
Varidhi Nauriyal ◽  
Benjamin Ueberroth ◽  
Adjoa Zakhia ◽  
Erica Herc

2020 ◽  
Vol 26 (7) ◽  
pp. 1636-1637 ◽  
Author(s):  
Marion Blaize ◽  
Julien Mayaux ◽  
Cécile Nabet ◽  
Alexandre Lampros ◽  
Anne-Geneviève Marcelin ◽  
...  

2015 ◽  
Vol 157 (12) ◽  
pp. 2221-2222 ◽  
Author(s):  
André Beer-Furlan ◽  
Leonardo Balsalobre ◽  
Eduardo A.S. Vellutini ◽  
Aldo C. Stamm

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Ulku Ergene ◽  
Zeynep Akcali ◽  
Demircan Ozbalci ◽  
Nalan Nese ◽  
Sebnem Senol

Invasive aspergillosis is a major cause of morbidity and mortality in immunocompromised patients. Many cases of pulmonary, cutaneous, cerebral, and paranasal sinus aspergillosis in immunocompetent patient were defined in literature but disseminated aspergillosis is very rare. Here we present an immunocompetent case with extrapulmonary disseminated aspergillosis due toAspergillus niger, totally recovered after effective antifungal treatment with voriconazole.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
S. Guglielmetti ◽  
C. M. Jaccard ◽  
K. Mühlethaler ◽  
A. Bigler ◽  
D. Springe ◽  
...  

Invasive aspergillosis represents a clinical picture frequently associated with host’s immunosuppression which usually involves a high morbidity and mortality. In general, the most frequent fungal entry is the lungs with secondary hematogenous dissemination, but there are other hypotheses like a gastrointestinal portal of entry. There are some rare publications of cases with invasive aspergillosis in immunocompetent patients. We present the case of an immunocompetent patient without any risk factors except for age, ICU stay, and surgical intervention, who developed a septic shock by invasive gastrointestinal aspergillosis as primary infection. Due to the unusualness of the case, despite all the measures taken, the results were obtained postmortem. We want to emphasize the need not to underestimate the possibility for an invasive aspergillosis in an immunocompetent patient. Not only pulmonary but also gastrointestinal aspergillosis should be taken into account in the differential diagnosis to avoid a delay of treatment.


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