scholarly journals The spatial distribution of Schistosoma mansoni infection in four regions of western Côte d’Ivoire

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Rufin K. Assaré ◽  
Ying-Si Lai ◽  
Ahoua Yapi ◽  
Yves-Nathan T. Tian-Bi ◽  
Mamadou Ouattara ◽  
...  

Schistosomiasis poses a considerable public health burden in sub- Saharan Africa and a sound understanding of the spatial distribution facilitates to better target control interventions. The objectives of this study were i) to assess the prevalence of <em>Schistosoma mansoni</em> among school-aged children in four regions of western Côte d’Ivoire; ii) to determine demographic, climatic and environmental factors that influence the distribution of <em>S. mansoni</em>; and iii) to map and predict the distribution of S. mansoni in non-sampled locations. Parasitological surveys were carried out in 264 schools from June to December 2011. In each school, we aimed to examine 50 children for <em>S. mansoni</em> infection using duplicate Kato-Katz thick smears. Schools were georeferenced using a hand-held global positioning system receiver. Demographic data were obtained from readily available school lists, while climatic and environmental data were extracted from open-access remote sensing databases. Multivariable, binary non-spatial models and a Bayesian geostatistical logistic regression model were used to identify demographic, climatic and environmental risk factors for S. mansoni infection. Risk maps were developed based on observed <em>S. mansoni</em> prevalences and using Bayesian geostatistical models to predict prevalences at non-sampled locations. Overall, 12,462 children provided a sufficiently large stool sample to perform at least one Kato-Katz thick smear. The observed overall prevalence of S. mansoni infection was 39.9%, ranging from 0 to 100% at the unit of the school. Bayesian geostatistical analysis revealed that age, sex, altitude and difference between land surface temperature at day and night were significantly associated with <em>S. mansoni</em> infection. The <em>S. mansoni</em> risk map presented here is being been used by the national schistosomiasis control programme for spatial targeting of praziquantel and other interventions.

Parasitology ◽  
2005 ◽  
Vol 131 (1) ◽  
pp. 97-108 ◽  
Author(s):  
G. RASO ◽  
B. MATTHYS ◽  
E. K. N'GORAN ◽  
M. TANNER ◽  
P. VOUNATSOU ◽  
...  

The objectives of this study were (1) to examine risk factors for Schistosoma mansoni infection among schoolchildren living in western Côte d'Ivoire, and (2) to carry forward spatial risk prediction and mapping at non-sampled locations. First, demographic and socio-economic data were obtained from 3818 children, aged 6–16 years, from 55 schools. Second, a single stool sample was examined from each child by the Kato-Katz technique to assess infection status of S. mansoni and its intensity. Third, remotely sensed environmental data were derived from satellite imagery and digitized ground maps. With these databases a comprehensive geographical information system was established. Bayesian variogram models were applied for spatial risk modelling and prediction. The infection prevalence of S. mansoni was 38·9%, ranging from 0% to 89·3% among schools. Results showed that age, sex, the richest wealth quintile, elevation and rainfall explained the geographical variation of the school prevalences of S. mansoni infection. The goodness of fit of different spatial models revealed that age, sex and socio-economic status had a stronger influence on infection prevalence than environmental covariates. The generated risk map can be used by decision-makers for the design and implementation of schistosomiasis control in this setting. If successfully validated elsewhere, this approach can guide control programmes quite generally.


Author(s):  
Mamadou Sanogo

Ivorian-Moroccan relations are not new because the diplomatic relations between the two countries have been established since August 16, 1962, but the interest of Morocco for Côte d'Ivoire has considerably strengthened during the royal visit of 19-21 March 2013 in Côte d'Ivoire, the first, since the beginning of his reign in 1999. Morocco is now refocusing its foreign policy on sub-Saharan Africa after the failure of Maghreb integration. This rapprochement resulted in Morocco's return to the African Union and its accession to ECOWAS.


Parasitology ◽  
2019 ◽  
Vol 147 (3) ◽  
pp. 287-294 ◽  
Author(s):  
Etienne K. Angora ◽  
Jean-François Allienne ◽  
Olivier Rey ◽  
Hervé Menan ◽  
André O. Touré ◽  
...  

AbstractSchistosomiasis is a neglected tropical disease, though it is highly prevalent in many parts of sub-Saharan Africa. While Schistosoma haematobium-bovis hybrids have been reported in West Africa, no data about Schistosoma hybrids in humans are available from Côte d'Ivoire. This study aimed to identify and quantify S. haematobium-bovis hybrids among schoolchildren in four localities of Côte d'Ivoire. Urine samples were collected and examined by filtration to detect Schistosoma eggs. Eggs were hatched and 503 miracidia were individually collected and stored on Whatman® FTA cards for molecular analysis. Individual miracidia were molecularly characterized by analysis of mitochondrial cox1 and nuclear internal transcribed spacer 2 (ITS 2) DNA regions. A mitochondrial cox1-based diagnostic polymerase chain reaction was performed on 459 miracidia, with 239 (52.1%) exhibiting the typical band for S. haematobium and 220 (47.9%) the S. bovis band. The cox1 and ITS 2 amplicons were Sanger sequenced from 40 randomly selected miracidia to confirm species and hybrids status. Among the 33 cox1 sequences analysed, we identified 15 S. haematobium sequences (45.5%) belonging to seven haplotypes and 18 S. bovis sequences (54.5%) belonging to 12 haplotypes. Of 40 ITS 2 sequences analysed, 31 (77.5%) were assigned to pure S. haematobium, four (10.0%) to pure S. bovis and five (12.5%) to S. haematobium-bovis hybrids. Our findings suggest that S. haematobium-bovis hybrids are common in Côte d'Ivoire. Hence, intense prospection of domestic and wild animals is warranted to determine whether zoonotic transmission occurs.


Author(s):  
Rufin K. Assaré ◽  
Mathieu I. Tra-Bi ◽  
Jean T. Coulibaly ◽  
Paul L. A. M. Corstjens ◽  
Mamadou Ouattara ◽  
...  

In low-endemicity settings, current tools for diagnosis and surveillance of schistosomiasis are often inaccurate in detecting true infection. We assessed the accuracy of an up-converting phosphor lateral flow circulating anodic antigen (UCP-LF CAA) test and a point-of-care circulating cathodic antigen (POC-CCA) urine cassette test for the diagnosis of Schistosoma mansoni. Our study was conducted in eight schools of western Côte d’Ivoire. Fifty children, aged 9 to 12 years, were enrolled per school. From each child, a single urine specimen and two stool specimens were collected over consecutive days for diagnostic workup. Urine samples were subjected to UCP-LF CAA and POC-CCA tests. From each stool sample, triplicate Kato-Katz thick smears were examined. Overall, 378 children had complete data records. The prevalence of S. mansoni, as assessed by six Kato-Katz thick smears, was 4.0%. The UCP-LF CAA and POC-CCA tests revealed S. mansoni prevalence of 25.4% and 30.7%, respectively, when considering trace results as positive, and prevalence of 23.3% and 10.9% when considering trace results as negative. In the latter case, based on a composite gold standard, the sensitivity of UCP-LF CAA (80.7%) was considerably higher than that of POC-CCA (37.6%) and six Kato-Katz thick smears (13.8%). The negative predictive value of UCP-LF CAA, POC-CCA, and six Kato-Katz thick smears was 92.8%, 79.8%, and 74.1%, respectively. Our results confirm that UCP-LF CAA is more accurate than Kato-Katz and POC-CCA for the diagnosis of S. mansoni in low-endemicity settings.


2016 ◽  
Vol 5 (1) ◽  
pp. 43-62 ◽  
Author(s):  
Paulo Gonçalves ◽  
Simplice Takoubo Kamdem

Sub-Saharan Africa is home to 24.7 million people living with HIV of an estimated total of 35.0 million people globally in 2013. It also accounts for almost 70% of the new HIV infections globally. In West Africa, Cote d'Ivoire has the highest HIV prevalence, or 3.7% of the 2012 population, and the two virus types (HIV-1 & HIV-2) are present. From an epidemiological standpoint, these unique attributes make Cote d'Ivoire unique. At the same time, existing HIV/AIDS modeling policies have being developed from the data of countries that do not have these peculiarities. This research develops a formal system dynamics model capturing the evolution of HIV/AIDS in Cote d'Ivoire for four decades, starting in 1990. The findings include a development of HIV/AIDS behavior pattern over time that led to the proposal of evidence-based policies.


2007 ◽  
Vol 12 (6) ◽  
pp. 709-723 ◽  
Author(s):  
Barbara Matthys ◽  
Andres B. Tschannen ◽  
Norbert T. Tian-Bi ◽  
Hermann Comoé ◽  
Salia Diabaté ◽  
...  

2019 ◽  
Vol 21 (Supplement_D) ◽  
pp. D47-D49 ◽  
Author(s):  
Kramoh Kouadio Euloge ◽  
Ekoua Daniel ◽  
Abina Audrey ◽  
Koffi Kouassi Florent ◽  
Koffi Djinguin Ben Justin ◽  
...  

Author(s):  
Giovanna Raso ◽  
Eliézer K N’Goran ◽  
Abale Toty ◽  
Anne Luginbühl ◽  
Cynthia A Adjoua ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document