scholarly journals Impact of anticholinergic burden on cognitive impairment, disability and malnutrition: a cross-sectional study among hospitalized older patients

2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Mariapaola Nastri ◽  
Giulio Bartoli ◽  
Paolo De Colle

The anticholinergic burden (ACB) is known to be associated with the worsening of functional and cognitive status. This study aims at demonstrating a correlation between the ACB and the malnutrition, given the widespread effect on the digestive tract of anticholinergic medications. From 2012 to 2018, 2843 patients were recruited among the new admissions to our Geriatric Unit. For each patient the activities of daily living (ADL), the instrumental activities of daily living (IADL), the mini mental state examination (MMSE), the cumulative illness rating scale (CIRS), the mini nutritional assessment (MNA) and the ACB of medications were evaluated. The correlations between the ACB and the ADL (P<0.001), the IADL (P<0.001), the MMSE (P<0.001) scores were confirmed, and a significant correlation was also found between the ACB and the MNA (P<0.001) score. The CIRS and the ACB scores resulted to be independent predictors of all outcomes considered, in a linear regression model adjusted for age, sex, comorbidity and number of prescribed drugs. Therefore, ACB seems to have by itself an impact on physical and cognitive functions and on nutritional status.

2020 ◽  
Author(s):  
Mohammad Rahanur Alam ◽  
Md. Shahadat Hossain ◽  
Akibul Islam Chowdhury ◽  
Marufa Akhter ◽  
Abdullah Al Mamun ◽  
...  

Background: The average life expectancy of the Bangladeshi population has been rising over the last decade due to the economic growth along with improved medicare. Although the increased number of geriatric people and their health is a matter of great concern, this issue remains unnoticed here. Objectives: To assess the nutritional status of the functionality and to analyze the association between nutritional status and functional ability of the selected Bangladeshi geriatric population. Methods: A community-based cross-sectional study was conducted among 400 participants, covering Chittagong, Noakhali, Comilla, and Jessore district of Bangladesh from December 2019 to February 2020. A standard and pretested questionnaire containing Mini Nutritional Assessment (MNA), Tinetti Performance Oriented Mobility Assessment (POMA), Activities of daily living scale (ADL), Lawton-Brody Instrumental Activities of Daily Living Scale (IADL), was used. Results: According to our study, The prevalence of malnutrition and people at risk of malnutrition have been 25.4% and 58.8%, respectively. In the case of functionality, 63.3% of subjects have high falling risk, and 61.8% of subjects can independently do their daily activities while 38.3% are dependent. Furthermore, almost 80% of people are dependent in terms of doing living skills. High risk of falling (OR=10.823; 95% CI: 5.846-20.37; p<0.001), poor skill in doing ADL (OR=6.206; 95% CI: 4.021-9.581; p<0.001), along with dependency in performing IADL (OR=4.477; 95% CI: 2.833-7.075; p<0.001) are significantly associated with malnutrition. Conclusions: Geriatric malnutrition can accelerate disability conditions, which can lead to early functional aging and subsequent loss in the quality of life.


Author(s):  
Amit Vasant Deshpande ◽  
Baer Philip Ravikumar

Background: Malnutrition among geriatrics remain undetected. The present study was conducted to assess the prevalence of malnutrition among geriatric outpatients and various factors associated with it.Methods: This cross-sectional study was done in Mamata medical college, Khammam, Telangana, in which we included geriatric patients (more than 60 years of age) who visited the outpatient clinic between January 2021 till March 2021. All study participants were evaluated for the following two domains of frailty: physical frailty and psychological frailty.Results: During the study period, we included 185 participants in the study. Based on mini nutritional assessment (MNA), 20% participants had normal nutrition, 55% were at risk of malnutrition and 25% had malnutrition. We observed that 59% of the participants with malnutrition were aged more than 80 years, 35% were smokers, 67% were living alone and 83% had comorbidities. It was observed that 67% and 57% of the study participants with malnutrition had impaired activities of daily living and impaired instrumental activities of daily living respectively. 54% of those malnutrition were depressed, which was significantly higher as compared to those with normal nutrition and those at risk of malnutrition (p value <0.05).Conclusions: The results of the present study demonstrate the nutritional status of geriatric outpatients is associated with physical as well as psychological frailty. Therefore, it is recommended that detailed nutritional assessment of patients of geriatric age groups should be conducted when they present in the outpatient clinic for any reason or complaint.


2021 ◽  
pp. 1-7
Author(s):  
Ya-Chen Lee ◽  
En-Chi Chiu

BACKGROUND: Nutritional status could affect functional capacity and reduce quality of life in patients with stroke. Although the associations between nutritional status, basic activities of daily living (BADL)/Instrumental ADL, and quality of life (QOL) in older people have been identified, the relationships have not yet been examined in patients with stroke, using the full Mini Nutritional Assessment (MNA) or MNA-short form (MNA-SF). OBJECTIVE: This study aimed to examine the relationship between nutritional status (using full MNA and MNA-SF), comprehensive ADL function, and QOL in patients with stroke. METHODS: Eighty-two patients with ischemic stroke participated in this cross-sectional design study. Each participant was assessed with the full MNA, MNA-SF, comprehensive ADL function (including Barthel Index and Frenchay Activities Index), and WHO Quality of Life-BREF (WHOQOL-BREF) once. RESULTS: The MNA-SF was only significantly correlated with the comprehensive ADL function (rho = 0.27, p = 0.013), whereas, the full MNA was found to be significantly correlated with the comprehensive ADL function and WHOQOL (rho = 0.24, p = 0.029 and rho = 0.30, p = 0.005). The MNA-SF was a significant predictor of comprehensive ADL function, accounting for 44% of the variance. The full MNA was the only significant predictor of the WHOQOL-BREF, explaining 17% of the variance. CONCLUSIONS: This study has revealed a relationship between nutritional status, comprehensive ADL function, and QOL among patients with stroke. Patients with stroke with better nutritional status had higher ADL function as well as better QOL. The MNA-SF was useful in predicting comprehensive ADL, whereas, the full MNA could be used to predict QOL. Knowledge and evidence of the association and predictive power of the MNA-SF and full MNA could guide clinicians to choose tools for assessing the nutritional status of patients with stroke more effectively.


2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Afifah Alfyanita ◽  
Rose Dinda Martini ◽  
Husnil Kadri

AbstrakPeningkatan Usia Harapan Hidup (UHH) penduduk Indonesia mengakibatkan peningkatan populasi usia lanjut (usila). Peningkatan usila berdampak terutama pada peningkatan angka ketergantungan dalam melakukan Aktivitas Kehidupan Sehari-hari (AKS). Penurunan tingkat kemandirian dalam melakukan AKS adalah salah satu faktor yang mempengaruhi status gizi usila. Tujuan penelitian ini adalah untuk menentukan hubungan tingkat kemandirian dalam melakukan AKS dan status gizi usia lanjut. Penelitian ini merupakan penelitian analitik observasional dengan rancangan cross-sectional study dan menggunakan kuisioner ADL Barthel dan Mini Nutritional Assessment (MNA) sebagai instrumen. Sebanyak 66 sampel diambil dari seluruh penghuni Panti Sosial Tresna Werdha Sabai Nan Aluih Sicincin yang memenuhi kriteria inklusi. Data berupa hasil tingkat kemandirian dan status gizi dianalisis menggunakan uji chi-square, dengan derajat kepercayaan 95%. Dari 66 subjek penelitian terdapat 36 usila (54,5%) tidak mandiri dalam melakukan AKS dan  39 usila (59,1%) memiliki status gizi berisiko malnutrisi. Uji chi-square menunjukkan nilai p adalah 0,015 (p<0,05). Kesimpulan penelitian adalah terdapat hubungan yang bermakna antara tingkat kemandirian dalam melakukan AKS dan status gizi pada usia lanjut di Panti Sosial Tresna Werdha Sabai Nan Aluih Sicincin.Kata kunci: tingkat kemandirian, aktivitas kehidupan sehari-hari, status gizi, usia lanjut AbstractThe increasing of life expectancy at Indonesia's population may lead to an increase in the elderly population. The main impact of this condition is the increasing of elderly dependency in performing Activity of Daily Living (ADL). Decreased level of independence in performing ADL is one of the factors that affect the nutritional status of elderly. The objective of this study was to determine the relationship between the level of independence in performing ADL and nutritional status of elderly.This research was an observational analytical study which designed as cross-sectional study. The instruments of this research were Barthel ADL and Mini Nutritional Assessment (MNA). 66 samples were taken from all the inhabitants of Panti Sosial Tresna Werdha Sabai Nan Aluih Sicincin who fulfill the inclusion criteria. The results of the level of independence and nutritional status were analyzed using chi-square test, with a degree of confidence of 95%. Of the 66 subjects there were 36 elderly (54.5%) not independent in performing ADL and 39 elderly (59.1%) were at risk of malnutrition. Chi-square test showed p value 0,015 (p<0.05).The conclusion is the significant relationship between the level of independence in performing ADL and nutritional status of the elderly in Social House Tresna Werdha Sabai Nan Aluih. Keywords: level of independence, performing Activity of Daily Living , nutritional status, elderly


2016 ◽  
Vol 96 (2) ◽  
pp. 167-175 ◽  
Author(s):  
Naoto Fukutani ◽  
Hirotaka Iijima ◽  
Takahiko Fukumoto ◽  
Daisuke Uritani ◽  
Eishi Kaneda ◽  
...  

Background Increasing evidence highlights potential associations between varus thrust and health domains associated with knee osteoarthritis (OA). Objective The aim of this study was to investigate the association between varus thrust and 2 subcategories—“pain and stiffness” and “activities of daily living (ADL)”—of the Japanese Knee Osteoarthritis Measure (JKOM). Design This was a cross-sectional study. Methods In total, 296 outpatients with knee OA visiting orthopedic clinics were enrolled. The inclusion criteria were age ≥50 years, medial knee OA and Kellgren-Lawrence (K/L) grade ≥1 in one or both knees, and the ability to walk independently. Standard posterior-anterior knee radiographs were measured for varus alignment. Participants were video recorded while walking and were evaluated for the presence or absence of varus thrust. Pain and stiffness of the knee joint and ADL were evaluated using the JKOM. Multivariate regressions (outcomes: pain and stiffness and ADL; predictor variable: varus thrust) were performed. Results Varus thrust was present in 46 (16.2%) of 284 patients. Multivariate regression analyses demonstrated that varus thrust is independently associated with pain and stiffness, adjusted for age, sex, body mass index, K/L grade, and varus alignment (β=.17, P=.005). However, the association between varus thrust and ADL was not significant (β=.11, P=.058). Based on sensitivity analyses, including participants of K/L grade 1 had little influence on this analysis. Limitations Only 16.2% of participants had a varus thrust. Moreover, a cause-effect relationship between varus thrust and pain and stiffness remains unknown due to the cross-sectional design of this study. Conclusions Varus thrust was associated with pain and stiffness in patients with medial knee OA. However, the association between varus thrust and ADL did not reach significance.


Author(s):  
Júlia Cristina Leite Nóbrega ◽  
Juliana Barbosa Medeiros ◽  
Tácila Thamires de Melo Santos ◽  
Saionara Açucena Vieira Alves ◽  
Javanna Lacerda Gomes da Silva Freitas ◽  
...  

Objective: To evaluate the association between socioeconomic factors, health status, and Functional Capacity (FC) in the oldest senior citizens in a metropolis and a poor rural region of Brazil. Method: Cross-sectional study of 417 seniors aged ≥80 years, data collected through Brazil’s Health, Well-being and Aging survey. FC assessed by self-reporting of difficulties in Activities of Daily Living (ADLs) and Instrumental Activities of Daily Living (IADLs). Chi-square tests and multiple logistic regression analyses were performed using “R” statistical software. Results: Socioeconomic and demographic inequalities in Brazil can influence FC in seniors aged 80 years and older. Comparatively, urban long-lived people had a higher prevalence of difficulties for ADLs and rural ones showed more difficulties for IADLs. Among urban oldest seniors, female gender and lower-income were correlated with difficulties for IADLs. Among rural oldest seniors, female gender, stroke, joint disease, and inadequate weight independently were correlated with difficulties for ADLs, while the number of chronic diseases was associated with difficulties for IADLs. Conclusion: Financial constraints may favor the development of functional limitations among older seniors in large urban centers. In poor rural areas, inadequate nutritional status and chronic diseases may increase their susceptibility to functional decline.


2014 ◽  
Vol 27 (5) ◽  
pp. 392-398 ◽  
Author(s):  
Andréa Mathes Faustino ◽  
Lenora Gandolfi ◽  
Leides Barroso de Azevedo Moura

Objective To verify whether there is a connection between the functional capacity of the elderly and the presence of violent situations in their daily lives. Methods A population-based cross-sectional study developed with 237 elderly individuals. Standard and validated research instruments were used. Results Mean age of 70.25 years (standard deviation of 6.94), 69% were female, 76% were independent in basic activities of daily living and 54% had a partial dependence on at least one instrumental activity. The most prevalent violence was psychological and the relation between being dependent on basic activities of daily living and suffering physical violence was statistically significant. Conclusion When the elderly needs assistance to perform self-care activities, there is a greater chance of exposure to a situation of abuse, such as physical violence.


2015 ◽  
Vol 28 (3) ◽  
pp. 231-240 ◽  
Author(s):  
Ana Luísa Moreira dos Santos ◽  
Teresa Maria de Serpa Pinto Freitas do Amaral ◽  
Nuno Pedro Garcia Fernandes Bento Borges

OBJECTIVE: To evaluate the prevalence of undernutrition in older adults aged >75 years living in communities and to identify the main factors independently associated with undernutrition. METHODS: A cross-sectional study was conducted using a random sample of family physicians' medical records of 86 older adults aged >75 years living in the community studied. Their nutritional status was evaluated using the Mini Nutritional Assessment. RESULTS: A total of 10.5% of the elderly were undernourished and 41.9% were at undernutrition risk. According to the logistic regression multivariable model, the following characteristics: being widowed (OR=6.7; 95%CI=1.8-24.6); being institutionalized (OR=12.6; 95%CI=1.7-90.5); or having a negative self-perception of health (OR=15.0; 95%CI=3.3-69.1) were independently associated with a significant increase of undernutrition risk. CONCLUSION: The current study shows that undernutrition is highly prevalent in Portuguese older adults aged >75 years living in communities. The major factors independently associated with their undernutrition are being widowed and institutionalized and having negative self-perception of health. The results obtained show that undernutrition and its associated factors are very serious problems for older adults and a challenge in their health care.


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