scholarly journals Secondary prevention in cognitive frailty: the Treviso Dementia Registry

2016 ◽  
Vol 2 (2) ◽  
Author(s):  
Maurizio Gallucci
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Secondary Prevention ◽  
Action Plan ◽  
Health Conditions ◽  
Future Research ◽  
Cognitive Frailty ◽  
Preclinical Phase ◽  
Number Of Patients ◽  
Dementia Registry

Dementia is one of the most disabling health conditions for older people. Increasing attention is paid to the preclinical phase such as cognitive frailty and mild cognitive impairment, and to the prevention programs designed to reduce the number of patients in the future. The aims of this brief report are therefore: i) to illustrate an action plan currently active in Treviso and that is aimed at secondary prevention in cognitive frailty subjects on the Treviso Dementia (TREDEM) Registry; ii) to highlight the results achieved by the TREDEM Registry up to now and how these can be used in future research.

Feasibility and Acceptance of Telerehabilitation among Older Adults with Mild Cognitive Impairment or Cognitive Frailty: A Scoping Review (Preprint)

2021 ◽  
Author(s):  
Nurul Hidayah Md Fadzil ◽  
Suzana Sahar ◽  
Roslee Rajikan ◽  
Devinder Kaur Ajit Singh ◽  
Arimi Fitri Mat Ludin ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Digital Health ◽  
Future Research ◽  
Intervention Programme ◽  
Cognitive Frailty ◽  
Hand Search ◽  
Adverse Health Outcomes ◽  
Cochrane Database

BACKGROUND Older adults are vulnerable towards cognitive frailty that can lead to adverse health outcomes such as cognitive frailty, falls, disabilities, hospitalizations and increased morbidity. With advancement of healthcare technology, there is a potential to manage and reverse cognitive frailty among older adults using a multi-domain intervention programme via telerehabilitation. OBJECTIVE In this review, we aimed to identify the feasibility and acceptance towards telerehabilitation and the common technology used for delivering telerehabilitation among older adults with mild cognitive impairment or cognitive frailty. METHODS Five research databases were searched: PubMed (EMBASE), Embase (Science Direct), Cochrane Database of Systematic Review, IEEE Xplore and Scopus. Articles published from January 2015 until October 2020 were selected. A hand search of JMIR Publications journals was also included RESULTS Of the 1758 articles retrieved, six studies were identified that involved implementation of telerehabilitation targeting older adults with cognitive frailty. Two articles were randomized controlled trials, one pilot study and three were qualitative studies. Telerehabilitation can improve quality of life among participants with mild cognitive impairment and cognitive frailty and found to be feasible as supportive digital platform in digital health care. Some types of technologies commonly used in the studies were smartphone or telephone with Internet, television-based assistive integrated technology, mobile application and videoconference. CONCLUSIONS Telerehabilitation utilization in managing cognitive frailty among older adults is still limited and more research is required to evaluate its feasibility and acceptability. Although telerehabilitation appears to be feasible and accepted among older adults with cognitive frailty, some social support in place is required. Future research should focus on evaluation of acceptance and cost effectiveness of multi-domain intervention via telerehabilitation among older adults with cognitive frailty.

ADAM10: Biomarker of mild cognitive impairment but not of cognitive frailty

2021 ◽  
Vol 149 ◽  
pp. 111303
Author(s):  
Izabela Pereira Vatanabe ◽  
Renata Valle Pedroso ◽  
Patricia Regina Manzine ◽  
Marcos Hortes Nisihara Chagas ◽  
Daiene de Morais Fabrício ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Frailty

scholarly journals Working Memory and Executive Function Decline across Normal Aging, Mild Cognitive Impairment, and Alzheimer’s Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Anna-Mariya Kirova ◽  
Rebecca B. Bays ◽  
Sarita Lagalwar
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Working Memory ◽  
Cognitive Impairment ◽  
Executive Function ◽  
Mild Cognitive Impairment ◽  
Executive Dysfunction ◽  
Normal Aging ◽  
Future Research ◽  
Neurological Differences

Alzheimer’s disease (AD) is a progressive neurodegenerative disease marked by deficits in episodic memory, working memory (WM), and executive function. Examples of executive dysfunction in AD include poor selective and divided attention, failed inhibition of interfering stimuli, and poor manipulation skills. Although episodic deficits during disease progression have been widely studied and are the benchmark of a probable AD diagnosis, more recent research has investigated WM and executive function decline during mild cognitive impairment (MCI), also referred to as the preclinical stage of AD. MCI is a critical period during which cognitive restructuring and neuroplasticity such as compensation still occur; therefore, cognitive therapies could have a beneficial effect on decreasing the likelihood of AD progression during MCI. Monitoring performance on working memory and executive function tasks to track cognitive function may signal progression from normal cognition to MCI to AD. The present review tracks WM decline through normal aging, MCI, and AD to highlight the behavioral and neurological differences that distinguish these three stages in an effort to guide future research on MCI diagnosis, cognitive therapy, and AD prevention.

scholarly journals Patterns of Semantic Memory Impairment in Mild Cognitive Impairment

2008 ◽  
Vol 19 (1-2) ◽  
pp. 35-40 ◽  
Author(s):  
Sven Joubert ◽  
Olivier Felician ◽  
Emmanuel J. Barbeau ◽  
Mira Didic ◽  
Michel Poncet ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Semantic Memory ◽  
Memory Impairment ◽  
Conceptual Knowledge ◽  
Famous People ◽  
Public Events ◽  
Preclinical Phase ◽  
Study Support

Although the semantic memory impairment has been largely documented in Alzheimer's disease, little is known about semantic memory in the preclinical phase of the disease (Mild Cognitive Impairment). The purpose of this study was to document the nature of semantic breakdown using a battery of tests assessing different aspects of conceptual knowledge: knowledge about common objects, famous people and famous public events. Results indicate that all domains of semantic memory were impaired in MCI individuals but knowledge about famous people and famous events was affected to a greater extent than knowledge about objects. This pattern of results suggests that conceptual entities with distinctive and unique properties may be more prone to semantic breakdown in MCI. In summary, results of this study support the view that genuine semantic deficits are present in MCI. It could be useful to investigate the etiological outcome of patients failing or succeeding at such tests.

Mild Cognitive Impairment: An Overview

CNS Spectrums ◽  
2008 ◽  
Vol 13 (1) ◽  
pp. 45-53 ◽  
Author(s):  
Ronald C. Petersen ◽  
Selamawit Negash
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Normal Aging ◽  
Future Research ◽  
Community Based ◽  
Cognitive Changes ◽  
Nutritional Interventions ◽  
Transitional State ◽  
Research Perspectives ◽  
Early Dementia

ABSTRACTMild cognitive impairment (MCI) refers to the transitional state between the cognitive changes of normal aging and very early dementia. MCI has generated a great deal of research from both clinical and research perspectives. Several population- and community-based studies have documented an accelerated rate of progression to dementia and Alzheimer's disease in individuals diagnosed with MCI. Clinical subtypes of MCI have been proposed to broaden the concept and include prodromal forms of a variety of dementias. An algorithm is presented to assist the clinician in identifying subjects and subclassifying them into the various types of MCI. Progression factors, including genetic, neuroimaging, biomarker, and clinical characteristics, are discussed. Neuropathological studies indicating an intermediate state between normal aging and early dementia in subjects with MCI are presented. The recently completed clinical trials as well as neuropsychological and nutritional interventions are discussed. Finally, the clinical utility of MCI, and directions for future research are proposed.

Subjective Memory Complaints and Mild Cognitive Impairment

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1 ◽  
Author(s):  
M. Simoes ◽  
L.C. Castro ◽  
O. Ribeiro ◽  
T. Salgado ◽  
C. Paz
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
The Elderly ◽  
Future Research ◽  
Older Individuals ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Cross Sectional ◽  
Memory Complaints ◽  
Increased Risk

Background:Subjective Memory Complaints (SMC) are common in clinical practice. the clinical significance of these subjective complaints among older individuals is not well understood.Aim:To study and discuss the association between SMC and MCI, underlining the importance of an adequate clinical assessment of SMC in the elderly.Methods:Review of the literature.Results:There is no consistent definition of SMC in the literature. Some prospective studies showed an association with objective memory impairments, conceptualizing SMC as a Pre-Mild Cognitive Impairment. SMC are also currently considered to be a core feature of Mild Cognitive Impairment (MCI). Cross-sectional studies and longitudinal studies showed conflicting results concerning the association between SMC and MCI.Discussion:The understanding of the predictive value of SMC in cognitive decline is still poorly understood. It is important to define criteria aimed to increase specificity of memory complaints, allowing an earlier identification of populations with higher risk of MCI. Future research on this complex association is important to identify SMC individuals at increased risk of conversion to MCI and dementia.

scholarly journals ‘Have you ever talked to any women with Turner syndrome?’ Using universal design and photo elicitation interviews in research with women with mild cognitive impairment

2019 ◽  
Vol 12 (2) ◽  
pp. 205979911984193
Author(s):  
Kriss Fearon
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Turner Syndrome ◽  
Research Design ◽  
Research Method ◽  
Universal Design ◽  
Research Process ◽  
Research Literature ◽  
Photo Elicitation ◽  
Future Research

A growing body of methodological research literature demonstrates the importance of adapting research design to address the specific needs of participants from minority groups. The aim is to treat participants more respectfully during the research process and to enhance participation, ensuring the findings more closely reflect participants’ views and experience. However, there is an absence of work examining the needs of research participants with Turner syndrome, a chromosome disorder linked with mild cognitive impairment and its potential impact on research interviews. This article draws on a study of reproductive decision-making in women with Turner Syndrome and mothers of girls with Turner syndrome to consider ways to improve research access and to make methodological adaptations for this group of participants. There is little qualitative research on the experience of living with Turner syndrome or its associated experience of infertility. Most of the small number of studies that exist do not describe whether the research method was adapted to accommodate the psychosocial features of Turner syndrome. Yet, these features, which include social cognition issues and anxiety, may have an impact on women’s ability to participate fully in a research interview and consequently on the quality of the data. This article fills a gap in research describing the use of adaptions with women with Turner syndrome, which may be of use to researchers and practitioners working with this group. It describes how a novel approach to research adaptations, universal design, was used to identify and incorporate adaptions into the research design, both through the choice of photo elicitation interviews as a research method and through adjustments made at each stage of the research process. It discusses how adaptions worked to overcome barriers to participation and how effective this was, concluding with suggestions for applying this approach in future research.

scholarly journals Using a cognitive orthosis to support older adults during meal preparation: Clinicians’ perspective on COOK technology

2020 ◽  
Vol 7 ◽  
pp. 205566832090907 ◽  
Author(s):  
Amel Yaddaden ◽  
Mélanie Couture ◽  
Mireille Gagnon-Roy ◽  
Patricia Belchior ◽  
Maxime Lussier ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Impairments ◽  
Occupational Therapists ◽  
Risky Behaviors ◽  
Future Research ◽  
Learning Abilities ◽  
Meal Preparation ◽  
Functional Profiles

Introduction Occupational therapists promote safety and autonomy of older adults with cognitive impairments. A technology, named COOK, offers support on a touch screen installed next to the stove to support task performance while correcting risky behaviors. We aimed to document (1) the functional profiles according the diagnosis (2) the types of interventions used to increase autonomy in the kitchen (3) the facilitators and obstacles to the implementation of COOK with this clientele. Methods Four focus groups were conducted with occupational therapists ( n = 24) and were transcribed and analyzed using thematic analysis, including coding and matrix building. Results Occupational therapists identified different (1) functional profiles and (2) interventions for both diagnoses. The use of COOK (3) could be more beneficial in mild cognitive impairment, as many barriers occur for the use in Alzheimer’s disease. Some parameters, such as digital control of the stove and complex information management, need to be simplified. Discussion According to occupational therapists, this technology is particularly applicable to people with mild cognitive impairment, because this population has better learning abilities. Conclusion This study documented the specific needs of older adults with cognitive impairments as well as interventions used by occupational therapists. The perspectives of caregivers should be captured in future research.

Mild cognitive impairment: a history and the state of current diagnostic criteria

2014 ◽  
Vol 27 (2) ◽  
pp. 199-211 ◽  
Author(s):  
Adam Gerstenecker ◽  
Benjamin Mast
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Diagnostic Criteria ◽  
Research Literature ◽  
The State ◽  
Clinical Vignette ◽  
Daily Functioning ◽  
Diagnostic Classification ◽  
Future Research

ABSTRACTBackground:Mild cognitive impairment (MCI) is a diagnostic classification used to describe patients experiencing cognitive decline but without a corresponding impairment in daily functioning. Over the years, MCI diagnostic criteria have undergone major changes that correspond to advancements in research. Despite these advancements, current diagnostic criteria for MCI contain issues that are reflected in the research literature.Methods:A review of the available MCI literature was conducted with emphasis given to tracing MCI from its conceptual underpinnings to the most current diagnostic criteria. A clinical vignette is utilized to highlight some of the limitations of current MCI diagnostic criteria.Results:Issues are encountered when applying MCI diagnostic criteria due to poor standardization. Estimates of prevalence, incidence, and rates of conversion from MCI to dementia reflect these issues.Conclusions:MCI diagnostic criteria are in need of greater standardization. Recommendations for future research are provided that could potentially bring more uniformity to the diagnostic criteria for MCI and, therefore, more consistency to the research literature.

Teaching Tai Chi to elders with osteoarthritis pain and mild cognitive impairment

2011 ◽  
Vol 10 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Jason Y. Chang, PhD ◽  
Pao-Feng Tsai, RN, PhD ◽  
Sheery Woods ◽  
Cornelia Beck, RN, PhD ◽  
Paula K. Roberson, PhD ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Knee Pain ◽  
Tai Chi ◽  
Cost Effective ◽  
Cognitively Impaired ◽  
Cognitive Frailty ◽  
Arthritis Foundation ◽  
Martial Art ◽  
Osteoarthritis Pain

This article describes the authors’ experience and strategies in teaching Tai Chi, a gentle exercise derived from an ancient Chinese martial art, to mildly cognitively impaired elders to relieve osteoarthritic knee pain. The 12-form Sun-style Tai Chi, a set of Tai Chi forms endorsed by the American Arthritis Foundation, was used in the program. Teaching Tai Chi to elders with mild cognitive impairment requires particular strategies tailored to their physical and cognitive frailty. When effectively taught, Tai Chi can be a unique and cost-effective intervention for elders with knee pain caused by osteoarthritis.

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