scholarly journals Iodinated contrast media exposure and incident hyperthyroidism and hypothyroidism in a community-based cohort

2013 ◽  
Vol 3 (2) ◽  
pp. 8 ◽  
Author(s):  
Connie M. Rhee ◽  
Katherine E. Lynch ◽  
Kambiz Zandi-Nejad ◽  
Elizabeth N. Pearce ◽  
Erik K. Alexander ◽  
...  
Keyword(s):  
Contrast Media ◽  
Media Exposure ◽  
Iodinated Contrast Media ◽  
Community Based ◽  
Iodinated Contrast

scholarly journals A case of acute-on-chronic liver failure promoted by thyrotoxicosis triggered due to iodinated contrast media exposure

2020 ◽  
Vol &NA; (6) ◽  
pp. 745-746
Author(s):  
Yan-Ting Ye ◽  
Jing-Sun Jiang ◽  
Lin-Jie Guo ◽  
Cheng-Wei Tang ◽  
Li-Bin Huang
Keyword(s):  
Contrast Media ◽  
Liver Failure ◽  
Media Exposure ◽  
Chronic Liver ◽  
Iodinated Contrast Media ◽  
Chronic Liver Failure ◽  
Iodinated Contrast

Contrast-induced acute kidney injury in acute ischaemic stroke patients

2020 ◽  
pp. 197140092097720
Author(s):  
Catarina Brito ◽  
Luís Falcão ◽  
Mário Raimundo ◽  
Sara Fernandes ◽  
Adriana Fernandes ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Contrast Media ◽  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Media Exposure ◽  
Kidney Injury ◽  
Iodinated Contrast Media ◽  
Stroke Patients ◽  
Stroke Imaging ◽  
Iodinated Contrast

Purpose The potential nephrotoxicity of intravenous iodinated contrast media is a major concern for acute ischaemic stroke imaging evaluation. This study aimed to assess the incidence of acute kidney injury after intravenous iodinated contrast media exposure in acute ischaemic stroke patients. Methods We conducted a retrospective cohort analysis between January 2012 and July 2018 to select adult patients admitted to the emergency department with acute ischaemic stroke. The exposed patients received a uniform intravenous dose of low osmolar non-ionic iodinated contrast media, as part of the imaging protocol for acute ischaemic stroke. The unexposed patients underwent a non-enhanced cranial computed tomography scan. Acute kidney injury was defined according to the Kidney Disease Improving Global Outcomes criteria, limited to the first 72 hours. Results A total of 161 and 105 patients were included in the exposed and unexposed groups, respectively. The median age was 72.8 years (interquartile range 20), 53% were men and 97% were white. Demographic and baseline characteristics were similar between the groups. The incidence of acute kidney injury between exposed ( n = 10, 6.2%) and unexposed ( n = 1, 1%) groups ( P = 0.073) was similar and contrast exposure was not a significant predictor of acute kidney injury. Conclusion Intravenous iodinated contrast media exposure during acute ischaemic stroke imaging protocols is not an independent predictor of acute kidney injury in patients with normal or near-normal renal function. Studies with larger sample sizes would help to clarify if patients with both cardiovascular risk factors and impaired renal function could benefit from prophylactic measures.

Development of polyclonal and monoclonal antibodies to iodinated contrast media

1988 ◽  
Vol 29 (6) ◽  
pp. 737-740 ◽  
Author(s):  
R. L. Siegle ◽  
W. L. McGuire ◽  
J. E. Peters
Keyword(s):  
Monoclonal Antibodies ◽  
Contrast Media ◽  
Iodinated Contrast Media ◽  
Iodinated Contrast

Chemistry of Iodinated Contrast Media (ICM): A Minireview

2020 ◽  
Vol 17 ◽  
Author(s):  
Maithili Pramod Joshi ◽  
Ameya Chaudhari ◽  
Prashant S. Kharkar ◽  
Shreerang V. Joshi
Keyword(s):  
Adverse Effects ◽  
Contrast Media ◽  
Aqueous Solubility ◽  
Synthetic Methods ◽  
Essential Medicines ◽  
World Health ◽  
Iodinated Contrast Media ◽  
Environmental Aspects ◽  
Iodinated Contrast ◽  
Health Organization

: Historically, the use of Iodinated Contrast Media (ICM) for diagnostic purposes, particularly radiography and computed tomography (CT), is well-known. Many of the ICM are included in the World Health Organization (WHO)’s List of Essential Medicines. Depending on the chemotype and the presence of ionizable functional group(s), the ICM are categorized in the ionic/nonionic monomers/dimers. The lipophilicity, aqueous solubility, viscosity and osmolality are major characteristics dictating their use for one procedure versus the other. Over last several decades, substantial advancement occurred in the design and development of novel ICM, solely to reduce their propensity to cause adverse effects. Given the nature of their acute usage, some of the agents with appreciable toxicity are still used. Understanding their chemistry aspects is crucial to appreciate, acknowledge and justify the usage of these extremely important torch-bearers of diagnostic agent’s class. The present review article presents an in-depth overview of the synthetic methods, therapeutic indications, potential adverse effects along with the commercial and environmental aspects of ICM. The safety and tolerability of these agents is a field that has gained significant importance, which is given due importance in the discussion.

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