scholarly journals Differential expression of KCNQ1 K+ channel in tubular cells of frog kidney

2010 ◽  
Vol 54 (1) ◽  
pp. 7 ◽  
Author(s):  
S. Ćirović ◽  
J. Marković-Lipkovski ◽  
J. Todorović ◽  
J. Nešović-Ostojić ◽  
M. Jović ◽  
...  
Keyword(s):  
Differential Expression ◽  
K Channel ◽  
Frog Kidney ◽  
Tubular Cells

Differential expression of K+ channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures

Neuron ◽  
1992 ◽  
Vol 8 (6) ◽  
pp. 1055-1067 ◽  
Author(s):  
Meei-Ling Tsaur ◽  
Morgan Sheng ◽  
Daniel H. Lowenstein ◽  
Yuh Nung Jan ◽  
Lily Yeh Jan
Keyword(s):  
Rat Brain ◽  
Differential Expression ◽  
K Channel ◽  
Down Regulation

Differential Expression of Voltage-Gated K + Channel Subunits in Adult Rat Heart

1995 ◽  
Vol 77 (2) ◽  
pp. 361-369 ◽  
Author(s):  
Dianne M. Barry ◽  
James S. Trimmer ◽  
John P. Merlie ◽  
Jeanne M. Nerbonne
Keyword(s):  
Differential Expression ◽  
Rat Heart ◽  
K Channel ◽  
Voltage Gated ◽  
Adult Rat

Handling of urea and related compounds by the renal tubules of the frog

1963 ◽  
Vol 205 (3) ◽  
pp. 483-488 ◽  
Author(s):  
Bodil Schmidt-Nielsen ◽  
Carolyn Ruth Shrauger
Keyword(s):  
Blood Concentration ◽  
Rana Catesbeiana ◽  
Renal Tubules ◽  
Urea Clearance ◽  
Frog Kidney ◽  
Active Secretion ◽  
Tubular Cells ◽  
Adult Frog ◽  
Plasma Arginine ◽  
Related Compounds

A high arginase activity is found in the kidney of the adult frog Rana catesbeiana which actively secretes urea. Urea accumulates in the kidney in concentrations around seven to eight times the blood concentration. To test whether the kidney arginase causes significant formation of urea in tubular cells at normal plasma arginine levels, C14 urea, chemical urea, and creatinine clearances were measured. C14 urea and chemical urea clearances were identical, both being about seven times the GFR. 2,4-Dinitrophenol (DNP) inhibited the active secretion of urea, but C14 and chemical urea clearances remained identical to each other. When arginine was administered, urea was formed in the kidney and excreted in the urine at the rate of 35 µm/g kidney hr. The chemical urea clearance was then about twice the C14 urea clearance. DNP administered with arginine caused the C14 urea clearance to fall below the GFR but did not inhibit the formation of urea as shown by the chemical urea clearance being three times the GFR. Compounds chemically related to urea were handled in different ways by the frog kidney. Acetamide and methylurea were not secreted and did not accumulate in the kidney. DNP had little or no affect on their excretion. Thiourea was found to be actively secreted and to accumulate in the kidney. DNP inhibited thiourea secretion. It is concluded that urea is normally actively transported across the tubular wall and that formation of urea in the tubular cells is insignificant.

Absence of KCNQ1-dependent K+ fluxes in proximal tubular cells of frog kidney

2007 ◽  
Vol 148 (3) ◽  
pp. 635-644 ◽  
Author(s):  
Dusan Cemerikic ◽  
Jelena Nesovic-Ostojic ◽  
Dusan Popadic ◽  
Aleksandra Knezevic ◽  
Simon Dragovic ◽  
...  
Keyword(s):  
Proximal Tubular Cells ◽  
Frog Kidney ◽  
Tubular Cells ◽  
Proximal Tubular
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