scholarly journals Self-reported adverse reactions associated with topical ophthalmic medication use: a cross-sectional survey

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Samuel Kyei ◽  
George Asumeng Koffuor ◽  
Elvis Ofori Ameyaw ◽  
Paul Ramkissoon ◽  
Daniel Adu-Agyeman
Keyword(s):  
Adverse Drug Reactions ◽  
Adverse Reactions ◽  
Drug Dosage ◽  
Clinical Population ◽  
Drug Reactions ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
High Prevalence ◽  
Drug Dosage Form ◽  
Blurry Vision

The aim of this study was to investigate self-reported adverse reactions associated with the use of topical ophthalmic medications. A cross-sectional survey, involving 500 ophthalmic patients recruited from three eye care facilities in the Central Region of Ghana was conducted. A structured questionnaire was administered to participants to collect data on demographics, name of drug, dosage form, and dosing frequency of ophthalmic medications used, as well as adverse reactions experienced. The pHs of frequently prescribed ophthalmic medications to the patients were measured. The prevalence of reported adverse drug reaction [predominantly burning sensation (55%), blurry vision (22%) and itching (13%)] was 44.8%. More Females reported adverse drug reactions than males (χ2=26.24, P<0.001). The aged reported more adverse reaction than others (P<0.01). Patients using cream ophthalmic medications reported more adverse drug reactions than those using other dosage forms (χ2=8.80, P=0.024). The pHs of the commonly prescribed ophthalmic medications measured ranged between 4.44-7.37 (desired: 6.6-7.8). There is a high prevalence of reported symptoms of adverse drug reactions among this clinical population attributable to the acid/base status of the drug agent.

scholarly journals Adverse Drug Reactions Reporting among Health Professionals in Government Hospitals in Katsina State, Nigeria

2021 ◽  
Vol 9 (3) ◽  
pp. 10-23
Author(s):  
Ayuba Daniel
Keyword(s):  
Adverse Drug Reactions ◽  
Health Professionals ◽  
Adverse Drug Reaction Reporting ◽  
Reporting Rate ◽  
Drug Reactions ◽  
National Agency ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Government Hospitals ◽  
Reporting Procedures

Medicines have the potential to cause Adverse Drug Reactions (ADRs) and therefore the need for health professionals to detect and spontaneously report to the National Agency for Food and Drug Administration and Control (NAFDAC) for further actions to ensure patients and public safety. The study was conducted to ascertain the proportion and reporting procedures of ADRs reported by health professionals in the Government Hospitals in Katsina State, Nigeria. This was a cross-sectional survey of 392 health professionals randomly selected from the 19 secondary hospitals in Katsina state. Data were collected through a self-administered structured questionnaire from 18th January to 19th February 2021 with a 98.7% and 1.3% response rate. Data were analyzed using STATA software Version 15.0. Descriptive statistics were used to describe the background characteristics of respondents, and the outcome, such as the proportion of ADR reported summarized in percentages, frequencies, and charts. There was only a 28.3% ADRs reporting rate, and 25.1% of health professionals who saw an ADRs case reported it by completing the ADRs form. The level of knowledge on ADRs reporting procedures was 58.3% among respondents. The main systemic challenge with ADRs reporting was the lack of access to the reporting form for ADRs. Therefore, there is a need to improve access to the reporting form in all the hospitals. Keywords: Adverse Drug Reaction Reporting, Government Hospitals, Health Professionals, Katsina state, Nigeria, Reporting Rate.

scholarly journals Community Pharmacist’s Knowledge, Practice and Barrier towards Reporting of Adverse Drug Reactions in Dammam, Saudi Arabia: A Cross-Sectional Survey Based Study

2020 ◽  
Vol 12 (1) ◽  
pp. 81-85
Author(s):  
Mohammad Daud Ali ◽  
Ayaz Ahmad ◽  
Yousif Amin Mohamed Hassan ◽  
Sherihan Ahmed Ghosn ◽  
Nuzhat Banu ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Adverse Drug Reactions ◽  
Drug Reactions ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Knowledge Practice

scholarly journals A cross-sectional survey of knowledge, attitude, and willingness to engage in spontaneous reporting of adverse drug reactions by Korean consumers

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Seungyeon Kim ◽  
Yun Mi Yu ◽  
Myoungsoon You ◽  
Kyeong Hye Jeong ◽  
Euni Lee
Keyword(s):  
Adverse Drug Reactions ◽  
Spontaneous Reporting ◽  
Drug Reactions ◽  
Cross Sectional Survey ◽  
Successful Operation ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Subjective Data ◽  
The Mean ◽  
Self Administered Questionnaire

Abstract Background Spontaneous reporting (SR) of adverse drug reactions (ADRs) from patients can be considered as a valuable activity providing both objective and subjective data. However, improving the rate of under-reporting has been a major challenge to ensure successful operation of the SR system. This study aimed to assess knowledge, attitude, and intent to report ADRs and explore the factors contributing to consumers’ reporting intent in South Korea. Methods Self-administered questionnaire was collected from a sex-, age-, and regionally stratified nationwide convenience sample of consumers using a commercial panel in December 2018. Univariate and multivariate logistic regression analyses were used to explore the factors contributing to the intent to report ADRs by consumers. Results A total of 1000 respondents were enrolled in the survey; 50.9% were males and the mean age was 44.4 (standard deviation, 13.3) years. While less than 15% of the respondents were aware of the SR system and even fewer (3.4%) had actual experience of SR, however, 59.2% expressed their intent to report ADRs. The positive attitude (adjusted odds ratio [aOR] 3.972, p < 0.001), awareness of the SR system (aOR 2.102, p < 0.01), self-efficacy for SR (aOR 1.956, p < 0.001), and experiences related to ADR counselling with healthcare professionals (OR 2.318, p < 0.001) are the significant factors contributing to reporting intent. Conclusions Findings of this study highlight the need for increasing the awareness of the SR system among consumers and empowering them to report ADRs by themselves, which would ultimately improve the drug-safety environment.

scholarly journals A study on drug induced cutaneous adverse drug reactions at a tertiary care hospital, Mysore, India

2019 ◽  
Vol 8 (4) ◽  
pp. 777
Author(s):  
Kishore M. S. ◽  
Shashikala S. Konnur
Keyword(s):  
Adverse Drug Reactions ◽  
Adverse Reactions ◽  
Tertiary Care ◽  
World Health ◽  
Uppsala Monitoring Centre ◽  
Care Hospital ◽  
Drug Reactions ◽  
Drug Induced ◽  
Cross Sectional ◽  
Physician Visits

Background: Drugs, however safe and efficacious, are associated with risk of adverse reactions. Adverse Drug Reactions (ADRs) are one of the leading causes of morbidity and mortality. ADRs was rated as the fifth leading cause of death among all diseases. Consequences of ADRs range from diminished quality of life, increased physician visits, hospitalizations, and even death. The objectives of the study were to obtain information about drug induced cutaneous adverse reactions and to establish the causal relationship.Methods: Observational cross sectional study, a total of 76 patients were recruited for the study,conducted in dermatology outpatient department of K R Hospital Mysore Medical College And Research Institute Mysore for 3 months. The drug reactions were recorded in ADR form of Central Drugs Standard Control Organisation (CDSCO). Causality was assessed using Naranjo algorithm and World Health Organization- Uppsala monitoring centre (WHO-UMC) criteria.Results: 76 patients with CADRs were included in the study during the 3 months study period. Most common age group with CADRs was 20-30 years; with 55.73% of females 20.26% male and the most common suspected drug group causing CADRs was antimicrobial 35.46%. And most common lesion is maculopapular rashes. According to Naranjos scale 67.30% of CADRs were probably caused by drugs.Conclusions: variety of drugs causes CADRs. Awareness among clinicians is required for active reporting of CADRs. Patients need to be educated for the cautious use of drugs causing ADRs to prevent the same.

POPULATION-BASED ESTIMATES OF COMMUNITY-BASED ADVERSE DRUG REACTIONS (ADRS) IN THE KINGDOM OF SAUDI ARABIA

2019 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Rasha A. Almubark ◽  
Thamir M. Alshammari ◽  
Amani S. Alqahtani ◽  
Nasser F. BinDhim
Keyword(s):  
Saudi Arabia ◽  
Adverse Drug Reactions ◽  
Reporting System ◽  
Population Based ◽  
Drug Reactions ◽  
Cross Sectional Survey ◽  
Kingdom Of Saudi Arabia ◽  
Community Based ◽  
Cross Sectional ◽  
Causes Of Mortality

Background: Adverse drug reactions (ADRs) represent important preventable causes of mortality, morbidity, hospitalization and increased healthcare costs. Traditionally, ADRs are studied in a clinical setting, but it is also important to estimate rates of ADRs in the community. The current study aimed to estimate population-based rates of ADRs in the community in the Kingdom of Saudi Arabia (KSA). Methods: A nationwide cross-sectional survey was conducted via registered pharmacists at community pharmacies across the 13 regions of KSA. The data were collected on an electronic online platform and included questions about participants’ demographics, health characteristics, experience with ADRs within the last 12 months and assess their knowledge about Saudi Food and Drug Authority (SFDA) reporting system. Results: Data collection was conducted between June and August 2018. Data from 5,228 surveys was analyzed. After weighting, the national annual rate of ADRs was estimated to be 28.00% (95% confidence interval 26.10% -30.00%). Of the respondents reporting an ADR, 371 (30.26%) reported that they were aware of the SFDA reporting system. Those who indicated they were aware, were asked if they had ever filed a report in the system; 53 (14.29%) said they had made a report. Conclusion: The results of this population-based estimates of community-based ADRs nationally in KSA showed that more than one quarter of the population had experienced ADR in the last 12 months. Future study is needed to better understand why these rates are higher in some regions than others, and what is needed to prevent high rates in subgroups such as women and those with chronic diseases.

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