scholarly journals Genotyping of Human Papilloma Virus (HPV) in female condyloma acuminata patient in Dr. Soetomo Hospital, Surabaya

2019 ◽  
Author(s):  
Afria Arista ◽  
Dwi Murtiastutik ◽  
Trisniartami Setyaningrum ◽  
Gondo Mastutik

Human Papilloma Virus (HPV) cause the most common sexually transmitted infection in women. HPV may lead to clinical manifestation as condyloma acuminata. The type of HPV are divided into two categories: low risk and high risk. Objective: To determine the type of HPV in female condyloma acuminata patient. Material and methods: A cross sectional study was conducted in Dermatology Venereology Outpatient Clinic Dr. Soetomo Hospital Surabaya from February, 2007 to May, 2007. A total of 13 female patients with condyloma acuminata were includ in this study. Nucleic acids amplification assays (Polymerase Chain Reaction) used to detect the HPV infection. Results: Condyloma acuminata mostly caused by HPV-11 (30,76%) and HPV-6 (23,07%). Only 1 patient in this study caused by HPV 18. 38% of condyloma acuminata in this study caused by multiple infection of HPV. Conclusion: Molecular assay are gold standard to identification of HPV in the condyloma acuminata patient.

2019 ◽  
Vol 4 (2) ◽  
pp. 27-32
Author(s):  
Fatjona Kamberi ◽  
Eva Muhaj

Objective: Human Papilloma Virus (HPV) infection is the most common sexually transmitted among young people of both sexes. It is also the main cause of cervical cancer. This study aimed at assessing students’ knowledge and health beliefs about HPV infection and the use of the vaccine.Methods: The sample of the cross-sectional study was 120 randomly selected nursing students from the Faculty of Public Health, University of Vlore “Ismail Qemali” Albania. Anonymous, self-administered questionnaire based on the literature and Health Belief Model, was used for data collection in May 2017. The questionnaire included assessment questions for students’ knowledge and health beliefs about HPV and vaccine use. Also, questions about socio-demographic characteristics were included. Data analysis included the calculation of averages, frequencies, and confidence intervals. P values ≤0.05 were accepted as statistically significant.Result: Mean age 20.3±2.2 years, 92.44 % of students were female. 65.83% of students know that HPV is a sexually transmitted infection and a vaccine is available to prevent it. Ambiguities and uncertainties exist in regard to screening with Pap test after vaccination. Perceived benefits are high for 50.83% of students. Perceived severity appeared low as only 25% of students agree that they may be affected by HPV. Statistical association, p =0.0347 was found between perceived risk and the year of study. The parents’ role in vaccination against HPV have a strong statistical association, p=0.0058 with the year of study as only 8.33 % of students in the third year agree with the fact that that parents do not allow them to be vaccinated against HPV. Conclusion: The study noted the student’s ambiguity and misconceptions about HPV infection. Low severity and lack of knowledge about the vaccine emphasizes that identifying their current level of knowledge and the main source of information are essential to provide comprehensive and appropriate health education.


Author(s):  
Xin Wang ◽  
Taifeng Du ◽  
Xiaoling Shi ◽  
Kusheng Wu

Cervical cancer (CC) is one of the most common causes of cancer-related deaths worldwide. CC is mainly caused by human papilloma virus (HPV), which can be prevented by vaccination. We conducted a cross-sectional study in secondary occupational health school (SOHS) through a questionnaire aimed to assess the awareness and knowledge regarding HPV infection of students. A total of 2248 students participated in the survey, 45.3% of them had heard about CC, while only 21.9% of them had heard about HPV; and 74.2% had no idea of the causal link between HPV infection and CC. Most participants displayed poor awareness and knowledge about HPV infection. The results suggested that age, grade, major, academic performance, etc. were correlated with higher awareness of CC, HPV and HPV infection (p < 0.05). In multivariable logistic analysis, third-grade students had the most increased awareness of CC (OR = 17.13, 95%CI: [8.11, 36.15]), HPV (OR = 6.59, 95%CI: [4.16, 10.43]) and HPV vaccine (OR = 2.78, 95%CI: [1.78, 4.32]) when compared to first-grade. Awareness and knowledge regarding HPV infection were insufficient among students in SOHS. As the future healthcare providers, these results highlight the need to supplement targeted education to improve their awareness and knowledge of HPV and vaccination.


2021 ◽  
Vol 9 ◽  
Author(s):  
Jacqueline Cortinhas Monteiro ◽  
Ricardo Roberto de Souza Fonseca ◽  
Tuane Carolina de Sousa Ferreira ◽  
Luana Lorena Silva Rodrigues ◽  
Andreza Reis Brasil da Silva ◽  
...  

Human papillomavirus (HPV) is the most common sexually transmitted infection in the world. Several studies have shown a higher prevalence of HPV infection in HIV-infected women. The aim of this study was to determine the prevalence and the genotype diversity of HPV infection in HIV-infected women. From April 2010 to December 2012 cervical specimens were collected from 169 HIV-infected women who screening for cervical cancer at Reference Unit in Belém. The detection of HPV infection was performed by nested PCR and HPV type was performed using a commercial system. The prevalence of HPV infection was 63.3%. Of the 47 genotyped samples, 40.4% was found positive for high risk-HPV 16 and 12.8% for high risk-HPV 52. HPV infection was predominant in the group of women with no incidence of cytological abnormalities and more prevalent in women of reproductive age, unmarried, low education level, and who reported use condoms during sexual intercourse. It was observed an association between HPV infection and independent variables, such as condom use, multiple sexual partners, and history of sexually transmitted diseases. High-risk types of HPV infection were prevalent in our study. Infection with multiple high-risk HPV genotypes may potentiate the development of cervical cancer in HIV-infected women.


Author(s):  
Aisha Nasser Al Saadi ◽  
Aisha Hamed Al Muqbali ◽  
Eihab Dawi

Objectives: This study aimed to assess knowledge of cervical cancer and its prevention among Omani women aged 20 to 65 years. Method: This analytic cross-sectional study took place at primary healthcare institutions, in the Al Buraimi governorate, Oman, between November 2018 I believe that in response to comment #5 too much information may have been removed from the Results section, therefore we return the first two paragraphs that were removed to the Results section and make them more concise during the copy editing stage.  and February 2019. The study was carried out on the basis of a predesigned, validated, and self-administered 55 question questionnaire. Results: Data from seven hundred and ninety-one completed questionnaires were included in the final analysis, which represents a response rate of 79.1% of the total. The results of the study indicated that 86.7 percent of surveyed women had previously heard of cervical cancer, and 13.0 per cent assumed the possibility of this disease to affect them in the future. The results showed that women had low awareness of the association between Human Papilloma Virus (HPV) and cervical cancer (24.7%). Participants considered HPV infection and initiation of sexual intercourse at an age younger than 17 years as the lowest risks associated with cervical cancer. The results also indicated that 63.8% of women were unaware of a vaccination 'against HPV related cervical cancer' and many of respondents were unaware of Pap test. Women aged over 30 years, those married, and those with a high level of education were more likely to be aware of cervical cancer. Conclusion: General knowledge of cervical cancer among women aged 20 to 65 years is insufficient. Young women aged 20-30 are largely unaware. Thus, concerted efforts are needed to promote awareness among women in Oman. Keywords: Cervical cancer, risk factor, Human Papilloma Virus, vaccine, Pap test.


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (3) ◽  
pp. 5-11 ◽  
Author(s):  
A L Tikhomirov ◽  
S I Sarsaniya ◽  
G A Filatova

The human papilloma virus (HPV) is the most common sexually transmitted infection. 440 million people in the world suffer from HPV infection of the genital. During the life of HPV, 50 to 80% of the sexually active population is infected, most often in the first years of sexual activity (the maximum prevalence is between 18-30 years of age). The treatment of subclinical forms of HPV epithelial lesions in 115 patients aged 26 to 42 years with a normal colposcopic pattern and the presence of coilocytosis was performed.


Author(s):  
Dnyanesh Limaye ◽  
Drashty Mehta ◽  
Shakshi Singh ◽  
Apurva Pardeshi ◽  
Tanvi Patil ◽  
...  

Background: Human papillomavirus (HPV) is a common sexually transmitted infection (STI) that may cause cervical cancer and other malignancies including those of the vulva, anus, vagina, penis, head and neck. In most Asian countries including India, cervical cancer is the second most common cancer in women. Awareness about HPV and cervical cancer, use of vaccines can be very helpful in prevention, control and early diagnosis of cervical cancer.Methods: A cross-sectional study was carried out among students from Mumbai University, India during May - June 2017. Two hundred students were approached to participate in the study of which 142 were selected to participate (males: 54; females: 88).  Pretested questionnaire was distributed and collected data was analyzed using IBM SPSS version 23.Results: Participants had fair knowledge (61% average) about HPV, whereas knowledge about symptoms, prevention and spread of HPV was very poor i.e. 18%. Knowledge about HPV vaccine was 50% and 78% participants had positive attitude for HPV vaccine.Conclusions: This study showed the lacunas in the pharmacy curriculum and urgent need to create awareness of HPV among bachelor of pharmacy students from Mumbai University.


Ciencia Unemi ◽  
2017 ◽  
Vol 10 (23) ◽  
pp. 112
Author(s):  
Edgar Rodas Neira ◽  
Betty Pazmino Gòmez ◽  
Roberto Coello Peralta ◽  
Julio Bermudez Bermudez ◽  
Karen Rodas Pazmino ◽  
...  

El Virus del Papiloma Humano (HPV) tiene un genoma ADN bicatenario perteneciente a la familia de los Papovaviridae, tiene capacidad oncogénica en una variedad de mamíferos, en especial el hombre, en el que se conoce más de 200 serotipos y representa una de las enfermedades de transmisión sexual más común, por su relación de patogenia oncológica. Se clasifica en tipos de alto y bajo riesgo oncológico (IARC), también se ha descrito otros tipos de infecciones como las orofaríngeas y amigdalitis. El objetivo de este estudio fue determinar el cribado de detección de anticuerpos IgG contra los genotipos 6, 11, 16 y 18 del virus mencionado, mediante la técnica serológica de Microelisa. Mediante un estudio descriptivo, prospectivo y transversal, realizado en el primer semestre del año 2015 en el Sector Gary Esparza del cantón Babahoyo, provincia de Los Ríos, Ecuador, de un universo de 250 habitantes se tomaron muestras sanguíneas a 97 mujeres mayores de 20 años y determinó 8 casos positivos (8.25%), con ello se estableció el primer diagnóstico serológico en el país, lo que constituye una herramienta de detección preliminar o screening de un gran número de muestras. ABSTRACT The Human Papilloma Virus (HPV) is a virus that has a double-stranded DNA genome belonging to the Papovaviridae family. It has oncogenic ability in a variety of mammals, especially man, in which more than 200 serotypes are known and represents one of the most common sexually transmitted diseases because of its relation to oncological pathogenesis.  It is classified into high and low cancer types (IARC), other types of infections such as oropharyngeal and tonsillitis have also been described. The objective of this study was to determine the screening of IgG antibodies against Human Papilloma Virus genotypes 6, 11, 16 and 18 using the Microelisa serological technique. A descriptive, prospective and cross-sectional study was carried out during the first semester of 2015 in the Gary Esparza Sector of Babahoyo, Los Ríos province, with a population of 250 habitants. Blood samples were taken from 97 women with 20 years old, being determined 8 positive cases (8.25%), establishing the first serological diagnosis in the country, which is a tool for preliminary screening or screening of a large number of samples.


2021 ◽  
pp. 58-58
Author(s):  
Suzana Mlinar

Background/Aim: Human papillomaviruses (HPV) is the most common sexually transmitted infection. Most HPV infections are transient and asymptomatic. Routine vaccination against HPV is the best prophylaxis against HPV infection. The aim of present study was to determine knowledge and risk factors about HPV infection, and the attitudes towards vaccination against HPV infection among nursing students. Methods: This cross-sectional study was conducted in a random sample of 175 nursing students. For statistical data analysis was done with t-test for and Mann-Whitney U test. Results: Most respondents (93.1%) knew that HPV infection may cause cervical cancer, and that it is a sexually transmitted infection (80.0%). Only 31.4% were aware that HPV may cause head and neck cancer and only 22.9% were aware that smoking is a risk factor for HPV infection. Male respondents (p=<0.05) and third-year respondents (p=<0.05) were significantly aware that men can be infected with HPV. Third-year respondents were significantly aware that early sexual intercourse increases the risk of HPV infection (p=<0.05), that HPV infection can be asymptomatic (p=<0.05). Respondents below 26 years (p=<0.05) and first-year respondents (p=<0.05) were significantly aware that men can also be vaccinated against HPV infection. Conclusion: The present study found that the respondents emphasised the importance of health education by nurses and vaccination against HPV infection. Due to the low vaccination rate of the population, preventive measures are needed to increase public awareness about vaccination against HPV, for which nurses are also responsible.


2018 ◽  
Vol 2 (2) ◽  
pp. 221-230
Author(s):  
Jacklen khoshaba ◽  
Salwa Mustafa ◽  
Muhannad Alazzawy

The aimed of the study was to evaluate the Seroprevalence of human papilloma virus (HPV) in aborted women. A cross-sectional study was carried out in Kirkuk city from 10th of March 2017 to 10th of July 2017 The number of aborted women understudy were 65 women who attended for curettage in Kirkuk general hospital. The control group who were matched to the patients studied included 30 normal pregnant women at the full term of pregnancy, women with Toxoplasma gondii , rubella and cytomegalovirus infections were excluded from the study. Five ml of blood was collected by vein puncture from each woman in the study, the obtained sera then organized to determine of HPV 16 E7 protein in patients and control using ELISA technique. The study showed that the highest rate of HPV infection (35.38%) was recorded among women with abortion comparing with the control group, with a highly significant relation. The study showed that 75.38% of women had aborted in the 1st trimester of pregnancy and the lowest rate of abortion 9.24% was in the 3rd trimester. The study showed that the highest rate of HPV infection was found in women with 1st trimester of abortion (38.78%) and the lowest rate was in the 3rd trimester of abortion. The study showed that the highest rate of HPV infection was recorded among aborted women who have suffered from one abortion during their marriage life. It was concluded that there was a significant relation of HPV with abortion spatially in women who were aborted in the first trimester of pregnancy.


Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1091
Author(s):  
Kendal Rosalik ◽  
Christopher Tarney ◽  
Jasmine Han

Human papilloma virus (HPV) is the most common sexually transmitted infection worldwide causing a variety of benign and malignant conditions. A significant portion of the global population is infected with HPV, with the virus attributed to causing up to 5% of cancers worldwide. Bivalent, quadrivalent, and nine-valent vaccinations exist to aid in the prevention of these diseases and have been proven to be effective at preventing both benign and malignant disease. While vaccination is readily accessible in more developed countries, barriers exist to worldwide distribution and acceptance of vaccination. Vaccination and screening of HPV infection when used in combination are proven and predicted to decrease HPV related pathology. Improvements in vaccination formulations, for treatment as well as prevention, are actively being sought from a variety of mechanisms. Despite these advancements, and the data supporting their efficacy, there has been substantial delay in obtaining adequate vaccination coverage. In reviewing these challenges and looking forward to new vaccine development—especially within the current pandemic—it is clear from the challenges of HPV we require methods to more effectively encourage vaccination, ways to dispel vaccination myths as they occur, and implement better processes for vaccine distribution globally.


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