scholarly journals Staphylococcus aureus colonization on antecubital non-exacerbated atopic dermatitis patient compared to healthy children

2019 ◽  
Author(s):  
Nur Khamidah ◽  
Evy Ervianti ◽  
Hari Sukanto
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Skin Barrier ◽  
Atopic Dermatitis Patient ◽  
Control Group ◽  
Healthy Children ◽  
Skin Microbiome ◽  
Cross Sectional ◽  
History Of ◽  
Cross Sectional Design

Atopic dermatitis is chronic pruritic inflammatory skin disease affects one third of children in the world, and the highest number of child`s skin problems in Indonesia. The complex role of the skin microbiome in the pathogenesis of atopic dermatitis is being elucidated. Interaction between skin barrier defects, and immunological factors can change the skin microbiome, and increased Staphylococcus aureus colonization. The aim of this study was to compare the colony of Staphylococcus aureus from antecubital fossa of non-exacerbated atopic dermatitis children to healthy children without history of atopic dermatitis. A comparative observational analytic with cross sectional design, examined antecubital swab culture from 17 non-exacerbated atopic dermatitis patients and 17 controls to investigate the presence of Staphylococcus aureus and density of the colonization. Staphylococcus aureus skin colonization was seen in 5 patients (29.41%) in non-exacerbated atopic dermatitis patients but none in control group (statistically significant with p=0.044), relative risk 2.417. All of positive colonization revealed moderate and heavy bacterial growth (104->105 cfu/cm2). This finding supports previous study that atopic dermatitis prone to colonized with Staphylococcus aureus.

scholarly journals ANALISIS PERBEDAAN JUMLAH NEUTROFIL ANTARA ANAK DOWN SYNDROME DAN ANAK SEHAT - Studi Pada SLB-C Widya Bhakti Semarang dan Mi Mirfa’ul Ulum

2017 ◽  
Vol 4 (1) ◽  
pp. 27
Author(s):  
Riezqia Ayu Wulandari ◽  
Sandy Christiono ◽  
Niluh Ringga
Keyword(s):  
Down Syndrome ◽  
Chromosome 21 ◽  
Control Group ◽  
Healthy Children ◽  
Cross Sectional ◽  
Children With Down Syndrome ◽  
Periodontal Infection ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design

Background: Down syndrome (DS) is a congenital disorder caused by abnormalities of chromosome 21, resulting in migration defect of neutrophils, specifically in GCF as a marker of increasing periodontal infection. This study aimed to analyze the difference in neutrophil numbers between down syndrome and healthy children.Method: This research was an analytic observational with cross sectional design, and divided into two groups. The control group is consisted of healthy children and the other is consisted of down syndrome children. GCF was taken using paper point number 45-50 for 30 seconds, then it smeared into object glass and painted with giemsa staining. Observations was done by light microscopy with 1000 times magnification.Result: The result of studies with p<0.05 was indicating a significant difference of neutrophil numbers between children with down syndrome and the healthy group.Conclusion: This study concluded that there was a difference in neutrophil numbers due to the migration defect of neutrophils in children with down syndrome, that can cause proneness to periodontal infections.

scholarly journals Faktor Risiko dan Faktor Pencetus yang Mempengaruhi Kejadian Asma pada Anak di RSUP Dr. M. Djamil Padang

2015 ◽  
Vol 4 (2) ◽  
Author(s):  
Isnaniyah Usman ◽  
Eva Chundrayetti ◽  
Oea Khairsyaf
Keyword(s):  
Risk Factors ◽  
Atopic Dermatitis ◽  
Nutritional Status ◽  
Inflammatory Disorder ◽  
Cross Sectional ◽  
Parental History ◽  
History Of ◽  
Asthma In Children ◽  
Cross Sectional Design ◽  
Inpatient And Outpatient Care

AbstrakAsma merupakan gangguan inflamasi kronik saluran pernafasan yang sering dijumpai pada anak. Penyakit ini memiliki banyak faktor risiko dan faktor pencetus. Beberapa diantara faktor tersebut adalah jenis kelamin, usia, riwayat atopi, makanan, perubahan cuaca, aktivitas, berat badan lahir, status gizi, pemberian ASI dan debu. Tujuan penelitian ini adalah untuk mengetahui faktor risiko dan faktor pencetus yang mempengaruhi kejadian asma pada anak di RSUP Dr. M. Djamil Padang. Ini adalah penelitian deskriptif dengan desain cross-sectional. Penelitian dilakukan dengan melakukan wawancara pada responden yang telah ditetapkan sebagai subjek penelitian. Subjek penelitian adalah seluruh pasien anak baik rawat jalan maupun rawat inap yang telah didiagnosis asma oleh dokter di RSUP Dr. M. Djamil Padang yang memenuhi kriteria. Penelitian dilakukan dari Februari sampai Maret 2013. Hasil penelitian menunjukkan bahwa faktor risiko dan faktor pencetus yang mempengaruhi asma pada anak adalah perubahan cuaca (65,91%), debu (63,64%), jenis kelamin (52,80%), makanan (43,19%), urtikaria pada anak (38,64%), rhinitis pada anak (34,09%), dermatitis atopi pada ibu (31,82%), dermatitis atopi pada anak (29,55%), aktivitas (27,27%), rhinitis pada ibu (22,72%), asma pada ibu (22,72%), urtikaria pada ayah (20,45%), berat badan lahir <2500 gram (15,91%) dan status gizi (obesitas) 2,28%. Berdasarkan hasil penelitian, kejadian asma banyak terjadi pada laki-laki, sebagian besar dipengaruhi oleh perubahan cuaca dan debu, riwayat atopi terbanyak pada anak adalah urtikaria, riwayat atopi terbanyak pada orangtua adalah dermatitis atopi pada ibu dan status gizi serta berat badan lahir pasien sebagian besar normal.Kata kunci: asma pada anak, faktor risiko, faktor pencetus AbstractAsthma is a cronic inflammatory disorder of respiratory tract that is often found in children. It has many risk faktor and inducer. Some of these risk are gender, age, history of atopy, food, climate change, activity, weight of birth, nutritional status, breastfeeding and dust. The objective of this study was to determine the risk factors and inducer that affect the incidence of asthma in children at the hospital of Dr. M. Djamil Padang. This was a descriptive study that use cross-sectional design. The study was conducted by interview to respondents who had been designated as a research subject. The subjects were all pediatric patients both inpatient and outpatient care that have been diagnosed as asthma by a physician in the hospital of Dr. M. Djamil Padang that have the criteria. The study done from February until March 2013. The result of the research showed that the risk factors and inducer that affect asthma in children are a weather change (65.91%), dust (63.64%), gender (52.80%), food (43.19%), urticaria in children ( 38.64%), rhinitis in children (34.09%), atopic dermatitis in women (31.82%), atopic dermatitis in children (29.55%), activity (27.27%), rhinitis in the mother ( 22.72%), asthma in women (22.72%), urticaria on the father (20.45%), birth weight <2500 g (15.91%) and nutritional status (obesity) 2.28%. Based on these results, the incidence of asthma more common in men, largely influenced by changes in the weather and dust, most history of atopy in children is urticaria, parental history of atopy was highest in atopic dermatitis and maternal.Keywords: asthma in chidren, risk factor, inducer

scholarly journals Skin care as a way to recover microbiome in patients with atopic dermatitis

2014 ◽  
Vol 11 (1) ◽  
pp. 17-22
Author(s):  
K S Pavlova
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Staphylococcus Epidermidis ◽  
Barrier Function ◽  
Skin Barrier ◽  
Skin Barrier Function ◽  
Skin Microbiome ◽  
Important Goal ◽  
Staphylococcus Haemolyticus ◽  
Genomic Technologies

Recently microbiome of the skin was characterized using genomic technologies in norm and in pathology. Microbiome of the affected skin in atopic dermatitis is characterized by a lack of the variety of bacteria, decrease of the Actinomycetes and Proteobacteries species and increase of Staphylococci colonization (Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus and others). Restoration of the skin barrier function is the most important goal in the overall concept of the atopic dermatitis treatment. Recent studies demonstrated the possibility of reductionof inflammation, xerosis, itching and restoration of skin microbiome of the affected areas by emollients use (Lipikar Baume AP, La Roche Posay), as a result of the skin barrier function improvement.

scholarly journals The possible link between coeliac and Kawasaki diseases in Brazil: a cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. e018803 ◽  
Author(s):  
Alessandra dos Santos Domingues ◽  
Nicole Selleski ◽  
Rosa Harumi Uenishi ◽  
Cristina Medeiros Ribeiro de Magalhães ◽  
Lenora Gandolfi ◽  
...  
Keyword(s):  
Systemic Vasculitis ◽  
Cross Sectional Study ◽  
Control Group ◽  
Healthy Children ◽  
Serological Tests ◽  
Cross Sectional ◽  
Nutrition Guidelines ◽  
History Of ◽  
Systemic Symptoms ◽  
Inflammatory Autoimmune Disease

BackgroundKawasaki disease (KD) is a self-limited acute systemic vasculitis of unknown aetiology that predominantly affects infants and young children eventually associated with immunological abnormalities. Coeliac disease (CD) is an inflammatory autoimmune disease characterised by a permanent gluten intolerance, which affects genetically susceptible individuals of any age group, and can cause intestinal and systemic symptoms. Association of CD with KD has been previously described in a single study that disclosed a surprisingly high prevalence of CD in children with a history of KD.ObjectiveTo confirm the existence of a higher prevalence of CD among individuals with a history of KD, which would turn the screening for CD in patients with history of KD highly advisable.SettingChildren with history of KD, diagnosed and followed at the Rheumatology Clinic of the Children’s Hospital of Brasilia (Brasilia, Brazil).ParticipantsThis study included 110 children with history of KD and a control group composed of 110 presumably healthy children.InterventionsParticipants underwent anti-transglutaminase and anti-endomysial antibodies tests and genetic typing for the presence of CD predisposing alleles (HLA-DQ2 and DQ8). Jejunal biopsy was performed when necessary, according the European Society of Paediatric Gastroenterology, Hepatology and Nutrition guidelines.ResultsDiagnosis of CD was confirmed in one (0.91%) patient with KD by positive serological tests, presence of predisposing alleles and CD typical lesions on duodenal biopsy. All serological tests were negative among the controls. The prevalence of CD predisposing alleles among patients with KD was 29.09%, similar to the prevalence found among controls, 33.64%.ConclusionThe detected CD prevalence (0.91%) does not confirm the existence of an association between KD and CD since this prevalence is similar to that found in the general population (≃1%).

DYSLIPIDEMIA IN THYROID DISORDERS

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Kashish Narula ◽  
Narendra Kumar Dara ◽  
Shyam Lal Meena
Keyword(s):  
Lipid Metabolism ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Control Group ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
Carbohydrate And Lipid Metabolism ◽  
History Of ◽  
Thyroid Profile ◽  
Basal Energy Expenditure

Background: Thyroid hormones influence nearly all major metabolic pathways. Their most obvious and well-known action is the increase in basal energy expenditure obtained by acting on protein, carbohydrate and lipid metabolism. The lipid metabolism is more influenced by the thyroid hormone. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results: The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: Dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Thyroid profile, Total cholesterol, Triglycerides and LDL

scholarly journals Seroprevalence of Antibodies against SARS-CoV-2 in Children with Juvenile Idiopathic Arthritis a Case-Control Study

2021 ◽  
Vol 10 (8) ◽  
pp. 1771
Author(s):  
Violetta Opoka-Winiarska ◽  
Ewelina Grywalska ◽  
Izabela Korona-Glowniak ◽  
Katarzyna Matuska ◽  
Anna Malm ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Disease Activity ◽  
Disease Activity Score ◽  
Juvenile Arthritis ◽  
Activity Score ◽  
Control Group ◽  
Healthy Children ◽  
Serum Samples ◽  
History Of ◽  
Novel Coronavirus

There is limited data on the effect of the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) on pediatric rheumatology. We examined the prevalence of antibodies against SARS-CoV-2 in children with juvenile idiopathic arthritis (JIA) and a negative history of COVID-19 and the correlation of the presence of these antibodies with disease activity measured by juvenile arthritis disease activity score (JADAS). In total, 62 patients diagnosed with JIA, under treatment with various antirheumatic drugs, and 32 healthy children (control group) were included. Serum samples were analyzed for inflammatory markers and antibodies and their state evaluated with the juvenile arthritis disease activity score (JADAS). JIA patients do not have a higher seroprevalence of anti-SARS-CoV-2 antibodies than healthy subjects. We found anti-SARS-CoV-2 antibodies in JIA patients who did not have a history of COVID-19. The study showed no unequivocal correlation between the presence of SARS-CoV-2 antibodies and JIA activity; therefore, this relationship requires further observation. We also identified a possible link between patients’ humoral immune response and disease-modifying antirheumatic treatment, which will be confirmed in follow-up studies.

Psychological, Structural, Social and Economic Determinants of Suicide Attempt: Risk Assessment and Decision Making Strategies

2021 ◽  
pp. 003022282110034
Author(s):  
Azam Farmani ◽  
Mojtaba Rahimianbougar ◽  
Yousef Mohammadi ◽  
Hossein Faramarzi ◽  
Siamak Khodarahimi ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Suicide Attempt ◽  
Suicide Attempts ◽  
Psychological Services ◽  
Cross Sectional ◽  
Economic Determinants ◽  
History Of ◽  
Cross Sectional Design ◽  
High Level ◽  
Risk Assessment And Management

The aim of this research was to conduct a risk assessment and management of psychological, structural, social and economic determinants (PSSED) in a suicide attempt. The sample consisted of 353 individuals who had a recorded history of suicidal attempt; and 20 professional individuals by purposive sampling method within a descriptive cross-sectional design. Worksheets for RAM and AHP were used for data collection in this study. The rate of suicide attempt was 7.21 per 100,000 population in this study. Analysis showed that depression and mental disorders; personality disorders; family problems; socio-cultural and economic problems; lack of awareness; and low level of education have a high level of risk for suicide attempts. Psychiatric and psychological services; awareness and knowledge of life skills; medical services to dysfunctional families; development of community-based planning for PSSED of suicide; and employment and entrepreneurship services may lower suicide attempt risk.

scholarly journals Treatment of atopic dermatitis using non-thermal atmospheric plasma in an animal model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ik Jun Moon ◽  
Mi Ra Yun ◽  
Hae Kyeong Yoon ◽  
Keon Hee Lee ◽  
Sun Young Choi ◽  
...  
Keyword(s):  
Animal Model ◽  
Atopic Dermatitis ◽  
Skin Barrier ◽  
Treated Group ◽  
Transepidermal Water Loss ◽  
Atmospheric Plasma ◽  
Therapeutic Modality ◽  
Skin Barrier Function ◽  
Control Group ◽  
Epidermal Thickness

AbstractCold atmospheric plasma (CAP) has been incorporated into various fields, including promotion of cutaneous wound healing. Atopic dermatitis (AD) is a chronic cutaneous condition characterized by inflammation-induced skin wounds and impaired skin barrier function. To investigate whether CAP may improve AD using an animal model. Dermatophagoides farinae extracts (DFE)-induced murine models of AD were used in this study. The plasma-treated group received a total of 6 CAP treatments during 2 weeks, while the control group did not receive any treatment. Differences in dermatitis severity, transepidermal water loss (TEWL), serum level of immunoglobulin (Ig) E and epidermal thickness were evaluated in both groups. The dermatitis severity was significantly improved by CAP treatment. TEWL was lower in the plasma-treated group compared with the non-treated control group. Serum Ig E dropped significantly after treatment with CAP. Difference in epidermal thickness of the ear skin was not significant between the plasma-treated and non-treated groups. Localized treatment of AD with CAP decreases dermatitis severity, TEWL, and serum Ig E level. These results show CAP’s potentials as a novel therapeutic modality for AD.

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