scholarly journals The efficacy of skin care products containing glutathione in delivering skin lightening in Indonesian women

2019 ◽  
Author(s):  
Kristiana Etnawati ◽  
Dwi Retno Adiwinarni ◽  
Devi Artami Susetiati ◽  
Yusuke Sauchi ◽  
Hitomi Ito
Keyword(s):  
Skin Color ◽  
Skin Care ◽  
Efficacy And Safety ◽  
Facial Skin ◽  
Cosmetic Products ◽  
Double Blind ◽  
Tingling Sensation ◽  
Asian Market ◽  
Skin Care Products ◽  
Skin Lightening

Glutathione is a potent antioxidant, which is widely used in skin care products for skin lightening especially in the Asian market. Presently, there was only one study of topical 2% oxidized glutathione (GSSG) in Philipino women, further study is needed to evaluate the efficacy and safety of cosmetic products containing glutathione. A double blind randomized clinical trial study was conducted in Yogyakarta, Indonesia, in 74 healthy Indonesian women, with average age 33.3 ± 5.9 years when subjects participated in the study. Each subject received supervised applications of Facial Wash twice a day, Day Cream with sunscreen and Night Cream. The subjects were divided into 3 groups based on the active ingredients of the tested products, which included glutathione reduced (GSH) 0.1%, GSH 0.5%, and without GSH. The effects of the tested products in lightening skin color and pigmentation were measured colorimetry with Chromameter Minolta for L*. Compared to a baseline, there were significant increases of L* (lightness) or ΔL* detected as early as week 2 in which group of GSH 0.1% were significantly higher compared to group of GSH 0.5% and group without GSH. Hyperpigmented lesions also improved, where GSH 0.5% group showed its superiority compared to others groups in week 8. The undesired effect were few minutes mild tingling sensation after night cream, and worsening of acne in all tested products. Conclusion skin care products containing GSH 0.1% and 0.5% were effective in facial skin lightening.

scholarly journals MOBILE APPLICATION FOR SKIN CARE PERSONALIZATION AT JASMINE BEAUTY CLINIC USING ANDROID

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Shinta Bomi Bomi ◽  
Cindy Himawan
Keyword(s):  
Mobile Application ◽  
Skin Care ◽  
Limited Time ◽  
Facial Skin ◽  
Treatment Combination ◽  
Number Of Patients ◽  
Skin Care Products

Jasmine Beauty Clinic is a beauty clinic that serves consultation on facial skin problems, maintain facial skin, facial treatments, and selling skin care products. Patients who want to have consultation, treatments, and buy skin care products must come to the clinic with limited time according to the schedule of the clinic. Patients are required to have a consultation with a dermatologist before getting treatment or buying products, but they have to wait long enough to get a consultation because of the large number of patients. Often some patients cannot have consultations because the dermatologist’s schedule is full. Based on this problem, an Android-based application is created to analyze the type of skin they have and get recommendation on which product and treatment combination they are supposed to use.

scholarly journals Frontal fibrosing alopecia: there is no statistically significant association with leave-on facial skin care products and sunscreens: reply from the authors

2016 ◽  
Vol 175 (6) ◽  
pp. 1408-1409 ◽  
Author(s):  
N. Aldoori ◽  
K. Dobson ◽  
C.R. Holden ◽  
A.J. McDonagh ◽  
M. Harries ◽  
...  
Keyword(s):  
Skin Care ◽  
Facial Skin ◽  
Skin Care Products

Frontal fibrosing alopecia: there is no statistically significant association with leave-on facial skin care products and sunscreens

2016 ◽  
Vol 175 (6) ◽  
pp. 1407-1408 ◽  
Author(s):  
S.D. Seegobin ◽  
C. Tziotzios ◽  
C.M. Stefanato ◽  
K. Bhargava ◽  
D.A. Fenton ◽  
...  
Keyword(s):  
Skin Care ◽  
Facial Skin ◽  
Skin Care Products

Frontal fibrosing alopecia: possible association with leave-on facial skin care products and sunscreens; a questionnaire study

2016 ◽  
Vol 175 (4) ◽  
pp. 762-767 ◽  
Author(s):  
N. Aldoori ◽  
K. Dobson ◽  
C.R. Holden ◽  
A.J. McDonagh ◽  
M. Harries ◽  
...  
Keyword(s):  
Skin Care ◽  
Questionnaire Study ◽  
Facial Skin ◽  
Skin Care Products

Facial skin care products and cosmetics

2014 ◽  
Vol 32 (6) ◽  
pp. 809-812 ◽  
Author(s):  
Zoe Diana Draelos
Keyword(s):  
Skin Care ◽  
Facial Skin ◽  
Skin Care Products

scholarly journals Controlling Systemic Inflammation by Careful Formulation of Topical Skin Care Products: Our Bodies Didn’t Evolve With All the Current Chemicals in Skin Care Products

2020 ◽  
Author(s):  
Greg Maguire
Keyword(s):  
Natural Products ◽  
Polyethylene Glycol ◽  
Chronic Inflammation ◽  
Systemic Inflammation ◽  
Skin Inflammation ◽  
Skin Care ◽  
Cosmetic Products ◽  
Review Of The Literature ◽  
Topical Formulations ◽  
Skin Care Products

Although man is still rapidly evolving, he has not co-evolved with all of the modern chemicals made by man, including those in cosmetic products. Care must be taken when formulating products so that commonly used ingredients, such as polyethylene glycol, can be substituted with safer ingredients to which man has adapted and that will not cause irritation and inflammation. This is especially important given that induction of skin inflammation will cause systemic inflammation. A review of the literature and of commercially available products was made to highlight techniques and products that remediate inflammation or induce inflammation. Many skin care products contain chemicals that induce irritation and inflammation that may lead to chronic, systemic inflammation. Well studied natural products, especially skin identical chemicals, may offer an advantage compared to recent man-made chemicals in cosmetic and topical formulations and help to reduce skin inflammation as well as skin derived systemic chronic inflammation.

Compatibility of topical agents with tumor treating fields (TTFields) for treatment of associated skin events in glioblastoma (GBM).

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e24126-e24126
Author(s):  
Moshe Giladi ◽  
Mario E. Lacouture ◽  
Uri Weinberg ◽  
Zeev Bomzon ◽  
Yoram Palti
Keyword(s):  
Electric Fields ◽  
Electrical Impedance ◽  
Skin Toxicity ◽  
Intermediate Frequency ◽  
Skin Care ◽  
Mitigation Strategies ◽  
Double Blind ◽  
Transducer Arrays ◽  
Skin Care Products

e24126 Background: TTFields are low intensity, intermediate frequency, alternating electric fields applied continuously using 2 pairs of skin-affixed transducer arrays. TTFields are FDA-approved in GBM and mesothelioma. The most common TTFields-related adverse event (AE) is mild-to-moderate dermatitis (beneath arrays), via long-term irritant exposure and local hyperhidrosis and occlusion exacerbation. Skin reaction mitigation strategies may improve quality-of-life (QoL) and ensure usage, as maximal survival benefits have been correlated with duration of use. Not all skin care products are TTFields compatible and may increase electrical impedance and lead to beneath array temperature increases. The aim of this in vivo study was to investigate the effects of 62 commercially available skin care products on electrical impedance during TTFields treatment. Methods: TTFields (200 kHz; optimal GBM frequency) were applied to rats using transducer arrays made of the same ceramic disks and hydrogels used in patients with GBM. To test electrical impedance effects, skin care products were applied to the skin immediately before array placement. The change in impedance relative to naïve skin was measured using the Optune device. Sixty-two commercially available products from 8 groups (adhesive removers, antibiotics, antiperspirants, antiseptics, cleansers, moisturizers, skin barriers, and topical corticosteroids) were evaluated. Results: Most lotions, soaps, foams, and solutions had minimal effect on electrical impedance, while petrolatum-based ointments significantly increased electrical impedance. Conclusions: TTFields compatible skin care products that did not affect electrical impedance were identified from each of the 8 groups and could be considered for further evaluation. All petrolatum-based ointments that were tested led to an increase in electrical impedance and are thus not recommended. Local application of TTFields compatible skin care products should be prospectively investigated in the clinical setting for their potential role in minimizing TTFields–related skin AEs. The randomized, double-blind PROTECT (PROphylactic skin Toxicity thErapy with Clindamycin and triamcinolone in GBM patients Treated with TTFields) study, should help establish which products best reduce skin AEs in patients with GBM and assess impact on QoL.

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