scholarly journals Seborrheic keratosis evolution into squamous cell carcinoma: A truly modified sun-related tumor? A case report and review of the literature

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Ioana Cimpean ◽  
Ivan Theate ◽  
Olivier Vanhooteghem
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Malignant Transformation ◽  
Histopathological Examination ◽  
Clinical Manifestations ◽  
Immunocompromised Patients ◽  
Review Of The Literature ◽  
Seborrheic Keratosis ◽  
Increased Risk

The incidence of seborrheic keratosis (SK) generally increases with age and are mostly localized on the trunk, face and neck, especially on sun-exposed areas. The association between SK and skin malignancies appears to be accidental, but in situ transformation occurs more frequently in sun-exposed areas. Histopathological examination of all SK cases should be considered, especially when SK lesions exhibit atypical clinical manifestations, such as ulceration and cresting, as they may herald malignant transformation. In addition, other features associated with malignant transformation include excoriations or hemorrhages identified on the lesion, modification and evolution of the macroscopic characteristics, and the presence of local erythema or pruritus. Immunocompromised patients exhibit an increased risk of malignant transformation, even when radiation is involved.

Simultaneous tumours of the larynx with the same histology: a case report and review of the literature

2005 ◽  
Vol 119 (3) ◽  
pp. 230-232
Author(s):  
Giancarlo Ottaviano ◽  
Gino Marioni ◽  
Rosario Marchese-Ragona ◽  
Filippo Marino ◽  
Alberto Staffieri
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Rare Occurrence ◽  
Review Of The Literature

Synchronous laryngeal malignancies are extremely uncommon. To the best of our knowledge, only four cases of primary synchronous squamous cell carcinoma (SCC) of the larynx are available in the literature. We report the case of a 52-year-old patient with simultaneous spindle-cell carcinoma and SCC in situ of the larynx. The pathogenesis, treatment and prognosis of this rare occurrence have been discussed.

scholarly journals A Rare Malignant Transformation of an Ovarian Cystic Teratoma: A Case Report

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Manju Rachel Mathew ◽  
Anita Ramdas ◽  
Susy S. Kurian ◽  
Linu Kuruvilla ◽  
Neelima Singh
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Germ Cell ◽  
Urothelial Carcinoma ◽  
Malignant Transformation ◽  
Histopathological Examination ◽  
Cystic Teratoma ◽  
Rare Occurrence ◽  
Urothelial Carcinomas ◽  
Cell Neoplasm

Mature cystic teratoma (MCT) is the commonest germ cell neoplasm of the ovary but malignant transformation is a rare occurrence (1-2%). Of these malignancies documented in literature the commonest are squamous cell carcinoma and adenocarcinoma. Urothelial carcinomas arising in an MCT are a rare occurrence and only 7 cases have been reported in literature. We report a case of an MCT which was complicated by the presence of urothelial carcinoma confirmed on histopathological examination.

scholarly journals Sebaceous carcinoma in situ as a diagnostic entity. Case report and review of the literature.

2018 ◽  
Vol 2 (2) ◽  
pp. 136-141 ◽  
Author(s):  
Leart Bërdica ◽  
Teona Bushati ◽  
Alfred Aga ◽  
Erisa Kola ◽  
Rustem Celami ◽  
...  
Keyword(s):  
Case Report ◽  
Carcinoma In Situ ◽  
Histopathological Examination ◽  
Diagnostic Category ◽  
Benign Neoplasm ◽  
Sebaceous Carcinoma ◽  
Review Of The Literature ◽  
General Pathology ◽  
Report Presentation

The concept of carcinoma in situ was first introduced by Broders in 1932 [1] and has been accepted as a well-established notion and diagnostic category in many organs and systems. However, sebaceous carcinoma in situ (SCIS) has not yet been recognized as a concept and diagnostic entity in general pathology or dermatopathology. Such lesions have been commonly misinterpreted as either a benign neoplasm or sebaceous carcinoma. Tumors that do not necessarily arise in pre-existing sebaceous glands are usually invasive at the time of diagnosis, and like their ocular counterparts, can exhibit pagetoid intraepidermal spread. Cases of purely in- situ extraocular sebaceous carcinoma are extremely rare and yet controversial until now.Recognizing sebaceous carcinoma in situ as a valid concept and diagnostic entity that will certainly help to avoid misinterpretation and subsequently under or over treatment of such lesions.In this article, we provide a case report presentation with histopathological examination and a critical review of the literature.

scholarly journals Sebaceous carcinoma in situ as a diagnostic entity. Case report and review of the literature.

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Leart Berdica ◽  
Teona Bushati ◽  
Alfred Aga ◽  
Erisa Kola ◽  
Rustem Celami ◽  
...  
Keyword(s):  
Case Report ◽  
Carcinoma In Situ ◽  
Histopathological Examination ◽  
Diagnostic Category ◽  
Benign Neoplasm ◽  
Sebaceous Carcinoma ◽  
Review Of The Literature ◽  
General Pathology ◽  
Report Presentation

The concept of carcinoma in situ was first introduced by Broders in 1932 [1] and has been accepted as a well-established notion and diagnostic category in many organs and systems. However, sebaceous carcinoma in situ (SCIS) has not yet been recognized as a concept and diagnostic entity in general pathology or dermatopathology. Such lesions have been commonly misinterpreted as either a benign neoplasm or sebaceous carcinoma. Tumors that do not necessarily arise in pre-existing sebaceous glands are usually invasive at the time of diagnosis, and like their ocular counterparts, can exhibit pagetoid intraepidermal spread. Cases of purely in- situ extraocular sebaceous carcinoma are extremely rare and yet controversial until now.Recognizing sebaceous carcinoma in situ as a valid concept and diagnostic entity that will certainly help to avoid misinterpretation and subsequently under or over treatment of such lesions.In this article, we provide a case report presentation with histopathological examination and a critical review of the literature.

Sebaceous carcinoma in situ as a diagnostic entity. Case report and review of the literature.

2018 ◽  
Vol 2 (2) ◽  
pp. 136-141
Author(s):  
Leart Berdica ◽  
Teona Bushati ◽  
Alfred Aga ◽  
Erisa Kola ◽  
Rustem Celami ◽  
...  
Keyword(s):  
Case Report ◽  
Carcinoma In Situ ◽  
Sebaceous Carcinoma ◽  
Review Of The Literature

scholarly journals Concurrent Bowen’s Disease of the Nipple and Breast Cancer

2020 ◽  
Vol 13 (3) ◽  
pp. 1410-1414
Author(s):  
Kei Yamaguchi ◽  
Ryoichi Matsunuma ◽  
Toko Kumeta ◽  
Sae Imada ◽  
Ryosuke Hayami ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Squamous Cell Carcinoma ◽  
Carcinoma In Situ ◽  
Histopathological Examination ◽  
Careful Examination ◽  
Bowen’S Disease ◽  
Ipsilateral Breast ◽  
Surgical Specimen ◽  
Bowen's Disease

Bowen’s disease is a squamous cell carcinoma in situ that commonly develops on the trunk, arms, or legs and has not spread beyond the top layer of skin. It seldom develops on the nipple. We report a patient who presented with Bowen’s disease of the nipple and had a concurrent breast cancer identified in the ipsilateral breast after careful examination. Histopathological examination of the surgical specimen after mastectomy confirmed the diagnoses.

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