scholarly journals Subclinical onychomycosis in patients with type II diabetes

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Amira Elbendary ◽  
Amira El Tawdy ◽  
Naglaa Zaki ◽  
Mostafa Alfishawy ◽  
Amr Rateb
Keyword(s):  
Early Detection ◽  
Type Ii Diabetes ◽  
Periodic Acid ◽  
Clinical Manifestations ◽  
Diabetic Patients ◽  
Type Ii ◽  
Periodic Acid Schiff ◽  
Cross Sectional ◽  
Uncontrolled Diabetes ◽  
Fungal Organisms

Fungal organisms could be present in the nail without any clinical manifestations. As onychomycosis in diabetics has more serious complications, early detection of such infection could be helpful to prevent them. We aim in this study to assess the possibility of detecting subclinical onychomycosis in type II diabetic patients and addressing possible associated neuropathy. A cross sectional, observational study included patients with type II diabetes with normal big toe nail. All were subjected to nail clipping of the big toe nail, followed by staining with Hematoxylin and Eosin and Periodic-Acid-Schiff (PAS) stains and examined microscopically. A total of 106 patients were included, fungal infection was identified in eight specimens, all were uncontrolled diabetes, and six had neuropathy. Using the nail clipping and microscopic examination with PAS stain to detect such subclinical infection could be an applicable screening test for diabetic patients, for early detection and management of onychomycosis.

Macroangiopathy in type II diabetes

1983 ◽  
Vol 104 (4_Suppl) ◽  
pp. S75-S78
Author(s):  
Antti Aro
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Type Ii Diabetes ◽  
Clinical Manifestations ◽  
Diabetic Patients ◽  
Type Ii ◽  
Peripheral Vascular ◽  
Middle Aged

ABSTRACT. Macroangiopathy is the most important cause of mortality and morbidity in type II diabetes. The atherosclerotic process in diabetes is similar to that found in non-diabetic subjects, but the laesions are more extensive and the clinical manifestations are more common in diabetic subjects than in the non-diabetic population. In diabetic patients from different populations, the prevalence of macroangiopathy is variable, and the relative frequency follows the pattern found in the respective non-diabetic populations. The relative risk of large vessel disease is in most populations higher for female than for male diabetics. Coronary heart disease is the most important manifestation of macroangiopathy while cerebrovascular disease and peripheral vascular disease are less frequent, although all these manifestations occur at increased frequency among middle-aged diabetic subjects. The incidence of peripheral vascular disease seems to increase with increasing duration of diabetes in middle-aged subjects, whereas coronary heart disease is particularly frequent in type II diabetes already at the time of the diagnosis. Key words: atherosclerosis, complications, diabetes mellitus, macroangiopathy, mortality.

scholarly journals Evaluation of sweet taste sensitivity in type-II Diabetes Mellitus patients

2020 ◽  
pp. 10-12
Author(s):  
Z. Naveen Kumar ◽  
B.N.S. Gowri Kumari
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Sweet Taste ◽  
Cross Sectional Study ◽  
Taste Sensitivity ◽  
Diabetic Patients ◽  
Type Ii ◽  
Cross Sectional ◽  
The Mean

Background: The objective is to evaluate the sweet taste sensitivity among type-II diabetes mellitus patients. Methods:  This is a cross sectional study consisted of 227 subjects (127 type-II Diabetic patients & 100 non diabetic individuals) of both the genders and age matched. Sweet taste sensitivity tests were done using different concentrations of glucose solution and compared among the diabetic patients with FBS more than 180mg/dl and diabetic patients with FBS less than 180mg/dl and also compared among the diabetic patients and non diabetic individuals.  The final concentration at which patient was able to perceive the taste was recorded. statistical analysis was done using Student’s unpaired T test. P­values of < 0.05 were considered to be statistically significant. Results: The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245 mg/l and the mean of sweet taste sensitivity in the diabetic patients with FBS <180 mg/dl was 2249mg/l with P<0.001 which is significant. The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l with P<0.01 which is significant. the mean of sweet taste sensitivity among diabetic patients with FBS <180 mg/dl was 2249 mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l  with P>0.05 which is not significant. Conclusion: In our study it was concluded that type-II Diabetes Mellitus patients have lesser sensitivity for the sweet taste. Loss of sensitivity leads to the increase in sugar consumption being the risk factor for worsening the disease.

scholarly journals Frequency of metabolic syndrome in patients with newly diagnosed Type II Diabetes at DOW University Hospital, Karachi-Pakistan.

2021 ◽  
Vol 28 (11) ◽  
pp. 1546-1551
Author(s):  
Muhammad Umar Khan ◽  
Akhtar Ali Baloch ◽  
Muhammad Arsalan ◽  
Syed Muhammad Adnan
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Type Ii Diabetes ◽  
University Hospital ◽  
Diabetic Patients ◽  
Type Ii ◽  
Newly Diagnosed ◽  
Cross Sectional ◽  
The Mean

Objectives: To determine the prevalence of metabolic syndrome in patients with newly diagnosed type 2. Study Design: Descriptive Cross Sectional study. Setting: Dow University Hospital. Period: October 2018 to January 2019. Material & Methods: A total 342 patients prevalence of metabolic syndrome in patients with newly diagnosed type II diabetes at Dow University Hospital, Karachi, Pakistan. Data was collected through a questionnaire which is designed to record the age, gender, BMI, FBS, Waist circumference, blood pressure, HDL and triglyceride level of newly diagnosed of diabetic patients. Frequency and percentages were calculated for these variables. SPSS version 21 was used to analyze the overall results. Results: A total of 342 new diagnosed diabetic were included in this study. 189 (55.26%) were males and 153 (44.74%) were females. The mean + SD of age was 48.21±9.28 years. The mean + SD of FBS was about 192±43 mg/dl with ranges from 98 to 482 mg/dl. The mean + SD of Serum TG was about 243±152 mg/dl with ranges from 189 to 325 mg/dl. The mean + SD HDL was about 38.9±9.23 mg/dl with ranges from 12 to 102 mg/dl. The mean + SD of waist circumference was about 110.5±11.90 cm. The mean + SD systolic & diastolic blood pressure was about 150 + 8.23 & 98 + 11.28 respectively. The mean + SD of BMI was 29.23+ 11.23. Metabolic syndrome was diagnosed in 252 (73.68%) in newly diabetic patients. Conclusion: Metabolic syndromes were highly associated with newly diagnosed type II diabetes patients.

scholarly journals Depression In Type 2 Diabetes Mellitus : A Cross-Sectional Study In Tertiary Care Teaching Hospital In India

2018 ◽  
Vol 2 (1) ◽  
pp. 24-28 ◽  
Author(s):  
P. Varma ◽  
R. Kant ◽  
P.P. Mishra
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Type Ii ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prevalence Of Depression

Introduction: In our country, number of patients of diabetes is increasing every year, so of depression. The emotional consequences of diabetes have been scrutinized in a number of studies and varying results about the association of depression with type 2 diabetes mellitus have been found. While depression may contribute to poor diabetes-related outcomes, diabetes and its complications may also contribute to poor depression outcomes. Both conditions may have common underlying biological and behavioural mechanisms, such as genetic susceptibility and common pathophysiological mechanism. AIM-To assess the prevalence and the factors associated with depression among the patients with type II diabetes mellitus.Materials and Methods: Single centre, descriptive, cross-sectional study conducted in tertiary care teaching hospital in India for a period of 8 months. 586 type II diabetes patients aged between 30 and 70 years were included. Patients taking mood elevator drugs, suffering from mental illness, gestational diabetes and type 1 diabetes were excluded from the study. Physicians Health Questionnare-9 (PHQ-9) with a score of ≥5 was used to make the diagnosis of depression.Results: Prevalence of depression among the diabetic patients found to be 49.48%. Many factors have been found to be associated with increased prevalence of depression among diabetic patients such as age, female gender, house wife, high BMI, diabetes duration, diabetes related complications, comorbid conditions and poor glycaemic control with poor follow-up.Conclusion: By managing both depression and diabetes concurrently, better outcome in patients and increase in overall quality of life can be achieved. Early detection and treatment of depression by effectively screening all diabetic patients for depression would help to bring down the severity of depression among these patients.Jour of Diab and Endo Assoc of Nepal 2018; 2 (1): 24-28

scholarly journals The Effects of Diabetic Duration on Lacrimal Functional Unit in Patients with Type II Diabetes

2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
Xiaoyu Zeng ◽  
Ying Lv ◽  
Zhongxiu Gu ◽  
Zhe Jia ◽  
Chen Zhang ◽  
...  
Keyword(s):  
Type Ii Diabetes ◽  
Functional Unit ◽  
Control Group ◽  
Diabetic Patients ◽  
Blink Rate ◽  
Type Ii ◽  
Corneal Sensitivity ◽  
Cross Sectional ◽  
Speed Score ◽  
Schirmer I Test

Purpose. To observe ocular surface changes in Type II diabetic patients with different disease durations and to understand the correlations between clinical parameters and diabetic durations. Methods. In this cross-sectional, prospective study, 51 healthy controls and 91 patients with Type II diabetes were enrolled. The diabetics were divided into 3 subgroups according to the disease duration, including duration <10 y group, 10 to 20 y group, and ≥21 y group. All subjects underwent clinical ocular examinations, including lipid layer thickness (LLT), blinking rate, tear meniscus height (TMH), noninvasive tear film break-up time (NI-BUT), meibography, superficial punctate keratopathy (SPK) scoring, corneal sensitivity, and Schirmer I test. They were also evaluated using the standard patient evaluation of eye dryness (SPEED) questionnaire. Results. SPEED score, meiboscore, SPK score, LLT, Schirmer I test, and corneal sensitivity differed significantly between the diabetic and healthy control groups. Further, SPEED score, Schirmer I test, corneal sensitivity, meiboscore, and blink rate significantly differed among the 3 diabetic subgroups and the control group. In diabetics, the SPEED score correlated with the SPK score, blink rate, TMH, and LLT; NI-BUT with TMH, LLT, and blink rate; TMH with the SPK score; Schirmer I test with the SPK score; and corneal sensitivity with the meiboscore. More importantly, the Schirmer I test, corneal sensitivity, and SPEED score negatively correlated with diabetic duration. Conclusion. Diabetic duration is an important factor that affects functions of the lacrimal functional unit in patients with Type II diabetes. The trends of changes in the ocular parameters vary along the course of diabetes.

scholarly journals Refractive errors in type II diabetic patients

2015 ◽  
Vol 3 (3) ◽  
pp. 17-21
Author(s):  
Shristi Shrestha ◽  
Khem Raj Kaini
Keyword(s):  
Refractive Error ◽  
Type Ii Diabetes ◽  
Age Groups ◽  
Female Gender ◽  
Diabetic Patients ◽  
Refractive Errors ◽  
Type Ii ◽  
Good Glycemic Control ◽  
Cross Sectional ◽  
Diabetic Population

INTRODUCTION: The prevalence of diabetes is increasing rapidly. Refractive error in the diabetic population is considered a main cause of visual impairment. So this study was conducted to find out the pattern of refractive errors in patients with type II diabetes mellitus in Western Nepal. MATERIAL AND METHODS: It was a hospital-based cross-sectional study. Three hundred forty eyes of one hundred seventy patients with type II diabetes underwent comprehensive eye examination including subjective and objective refraction and serum biochemistry. RESULTS: The mean refraction was -0.132±0.88 D. Emmetropia was seen in 49.7% of the patients, hypermetropia in 22.6%, myopia in 12.6%, and astigmatism in 15% of the patients. Older age groups had more hypermetropic refractive error (p<0.05). Female gender was a risk factor for hypermetropia (p=0.042). Good glycemic control was seen in 49.7%. There was statistically significant correlation between fasting blood sugar level and spherical equivalent refraction (p<0.05, r = -0.115). CONCLUSION: The present hospital-based study noted a refractive error in 50.3% among diabetic population in Pokhara with hypermetropia being the most common type (22.6%) than myopia (12.6%) and astigmatism (15%).

scholarly journals Frequency of dyslipidemia in patients with type ii diabetes mellitus presenting in DHQ Teaching Hospital, Sahiwal.

2020 ◽  
Vol 27 (07) ◽  
pp. 1433-1437
Author(s):  
Abbas Humayun ◽  
Khalil Ahmad ◽  
Rana Aamir Diwan ◽  
Muhammad Saiful Malook
Keyword(s):  
Diabetes Mellitus ◽  
Teaching Hospital ◽  
Type Ii Diabetes ◽  
Blood Lipid ◽  
Diabetic Patients ◽  
Type Ii ◽  
Pathology Laboratory ◽  
Cross Sectional ◽  
Screening Programs

Dyslipidemia is major risk factor for cardiovascular disease in diabetes mellitus (DM). Early detection and treatment of dyslipidemia in type 2 DM can prevent the risk for atherosclerosis. Objectives: To determine the frequency of dyslipidemia in patients with type 2 diabetes mellitus presenting in DHQ Teaching Hospital, Sahiwal for routine check-up. Study Design: Cross Sectional, Observational, Descriptive study. Setting: Medical Unit 1, DHQ Teaching Hospital, Sahiwal, Pakistan. Period: 05-05-2018 to 05-11-2018. Material & Methods: Total 180 patients fulfilling selection criteria were enrolled in the study. Blood samples were obtained and sent to the Pathology Laboratory of the hospital for assessment of lipid profile. Reports were assessed and if cholesterol>200mg/dl and triglyceride>150mg/dl, then dyslipidemia was labeled. All this information was recorded on pro-formas. Results: In this study dyslipidemia was diagnosed in 81(45%) patients. Frequency of dyslipidemia was higher in age group 51-60 years (44.4%) as well as among female patients (56.8%). Overweight patients and patients with normal BMI had the highest frequency of dyslipidemia. Conclusion: the results of this study showed high frequency of dyslipidemia among type II diabetic patients. Type II diabetes is very much common in our population so there is a need to design screening programs in which blood lipid levels screening should be monitored on regular intervals to rule out dyslipidemia timely and for effective and proper management with statin therapy.

scholarly journals Association of Hypertension and its risk factor in Type II diabetes mellitus patients

2021 ◽  
Vol 12 (1) ◽  
pp. 28-33
Author(s):  
Seema Singh ◽  
Nitin Ranjan Gupta ◽  
Syed Tahseen Raza ◽  
Avadh Kapoor ◽  
Pooja Singh
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Blood Pressure ◽  
Type Ii Diabetes ◽  
Diabetic Patients ◽  
Type Ii ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Cross Sectional

Background: There are few reports in India about the correlation of hypertension, its risk factors and its relationship with type II diabetes. Several studies have shown that Type II diabetes in India is increasingly widespread. Aims and Objective: The main purpose of this research is to determine the association between hypertension and type II mellitus diabetes. Materials and Methods: The Department of Physiology, Era Medical College & Hospital, Lucknow and the Department of Internal Medicine, Hind Institute of Medical Sciences and Research, Sitapur, performed a cross-sectional study on 520 patients with type II diabetes. The structured questionnaire was prepared to collect history of hypertension, social and demographical parameters and diabetes duration. A trained staff has measured anthropometric data like height, weight and also took blood pressure by digital blood pressure monitor (CITIZEN-CH-432). Results: This study indicated a significant (p<0.001) relationship between BMI and hypertension in diabetes mellitus II patients. This study has also shown significant relationship between physical activity and hypertension in diabetes mellitus patients. The logistic regression study demonstrated that hypertension in diabetes mellitus patients has been positively associated with age (p<10-4) sensitivity level (p<10-3) and period of diabetes (p<10-2). Conclusion: Hypertension is a common issue among diabetic Indians. This research focused primarily on the association of hypertension and its related risk factors in patients with diabetes. The study showed that hypertension in diabetic patients is associated with age, physical activity, awareness level and BMI. More studies on larger sample sizes are needed to validate the current findings.

scholarly journals Associations of Demographic, Clinical and Laboratory Profiles of Patients with type II Diabetes Mellitus with its Microvascular Complications in Bangladesh

2020 ◽  
Author(s):  
Mamunur Rashid ◽  
Abdul Mukit ◽  
Khawza Iftekhar Uddin Ahmed ◽  
Raqibul Mostafa ◽  
Sharmin Parveen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Microvascular Complications ◽  
Significant Risk ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Cardiac Autonomic Neuropathy ◽  
Diabetic Patients ◽  
Type Ii ◽  
Cross Sectional

Abstract Objective: The aim of this study was to investigate the associations of makers from demographic, clinical, and laboratory profiles with microvascular complications in a cohort of type II diabetic population in Bangladesh. Methods: In this cross-sectional study 103 participants [47 Men and 56 Women; Age 40~70 years] having type II diabetes for more than 10 years were randomly recruited during their routine visits to a major Diabetic Hospital in Dhaka, Bangladesh. The associations of prevalence of microvascular complications [Cardiac Autonomic Neuropathy(CAN), Diabetic Peripheral Neuropathy(DPN), Diabetic Nephropathy(Nep), Diabetic Retinopathy(Ret)] with demographic, clinical, and laboratory profiles were assessed by multivariate logistic regression (p<0.05 and Odds ratio (OR)> 1.0). Results: The prevalence rates of CAN, DPN, Ret and Nep were 68%, 43.69%, 6.8%, and 4.8% respectively. The overall prevalence of diabetic-associated microvascular complication is 94.36% in this cohort of diabetic patients. BMI (p=0.0330, OR=1.90) and HbA1c (p=0.0535, OR=3.08) were found to be the most significant risk factors in the development of all microvascular complications. However, HbA1c for CAN; HbA1c, Microalbuminuria and Urinary creatinine for DPN; years of Diabetes, Systolic blood pressure and albumin creatinine ratio for Nep, HbA1c and Microalbuminuria for Ret were found to be most significantly associated in this Diabetes patients’ cohort. Conclusion: The proportion of microvascular complications was found to be significantly high among patients with Type II diabetes mellitus in this cohort. Controlling HbA1c could help reduce all four types of complications. However, controlling microalbuminuria could prevent DPN and Ret. This emphasizes the need for screening and prevention program toward early, symptomless identification of type II diabetes microvascular complications.

Relationship between uric acid and creatinine in pre-diabetic and diabetic patients: Vidarbha region of Maharashtra

2020 ◽  
Vol 11 (3) ◽  
pp. 3412-3417
Author(s):  
Ranjit S. Ambad ◽  
Rakesh Kumar Jha ◽  
Lata Kanyal Butola ◽  
Nandkishor Bankar ◽  
Brij Raj Singh ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Type Ii Diabetes ◽  
Fasting Blood Glucose ◽  
General Medicine ◽  
Control Group ◽  
Diabetic Patients ◽  
Type Ii ◽  
Develop Type ◽  
Low Levels

Prediabetes is a glucose homeostasis condition characterized by decreased absorption to glucose or reduced fasting glucose. Both of these are reversible stages of intermediate hyperglycaemia providing an increased type II DM risk. Pre-diabetes can therefore be viewed as a significant reversible stage which could lead to type II DM, and early detection of prediabetes may contribute to type II DM prevention. Prediabetes patients are at high risk for potential type II diabetes, and 70 percent of them appear to develop Type II diabetes within 10 years. The present study includes total 200 subjects that include 100 Prediabetic patients, 50 T2DM patients and 50 healthy individual. Blood samples were collected from the subjects were obtained for FBS, PPBS, Uric acid and Creatinine estimation, from OPD and General Medicine Wards. Present study showed low levels of Serum Uric Acid in prediabetic and T2DM patients were decreased as compared to control group, while the level of creatinine in prediabetic and diabetic were elevated as compared to control group, were not statically significant. Serum Uric Acid was high in control group and low in prediabetic and diabetic patients. Serum creatinine was declined in control group and increased in prediabetic and diabetic patients with increasing Fasting blood glucose level.

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