scholarly journals Aneurysm wall enhancement in black blood MRI correlates with aneurysm size. Black blood MRI could serve as an objective criterion of aneurysm stability in near future

2018 ◽  
Author(s):  
Athanasios K. Petridis ◽  
Andreas Filis ◽  
Elias Chasoglou ◽  
Igor Fischer ◽  
Maxine Dibué-Adjei ◽  
...  

The increasing number of incidental intracranial aneurysms creates a dilemma of which aneurysms to treat and which to observe. Clinical scoring systems consider risk factors for aneurysm rupture however objective parameters for assessment of aneurysms stability are needed. We retrospectively analysed contrast enhancing behaviour of un-ruptured aneurysms in the black blood magnetic resonance imaging (MRI) in N=71 patients with 90 aneurysms and assessed correlation between aneurysm wall contrast enhancement (AWCE) and aneurysm anatomy and clinical scoring systems. AWCE is associated with aneurysm height and height to width ratio in ICA aneurysms. AWCE is correlated to larger aneurysms in every anatomical location evaluated. However the mean size of the contrast enhancing aneurysms is significantly different between anatomical localizations indicating separate analyses for every artery. Clinical scoring systems like PHASES and UIATS correlate positively with AWCE in black blood MRI. MRI aneurysm wall contrast enhancement is a positive predictor for aneurysm instability and should be routinely assessed in follow up of incidental aneurysms. Aneurysms smaller than 7 mm with AWCE should be followed closely with focus on growth, as they may be prone to growth and rupture.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jian Zhang ◽  
Anil Can ◽  
Pui Man Rosalind Lai ◽  
Srinivasan Mukundan ◽  
Victor M. Castro ◽  
...  

AbstractMorphological factors of intracranial aneurysms and the surrounding vasculature could affect aneurysm rupture risk in a location specific manner. Our goal was to identify image-based morphological parameters that correlated with ruptured basilar tip aneurysms. Three-dimensional morphological parameters obtained from CT-angiography (CTA) or digital subtraction angiography (DSA) from 200 patients with basilar tip aneurysms diagnosed at the Brigham and Women’s Hospital and Massachusetts General Hospital between 1990 and 2016 were evaluated. We examined aneurysm wall irregularity, the presence of daughter domes, hypoplastic, aplastic or fetal PCoAs, vertebral dominance, maximum height, perpendicular height, width, neck diameter, aspect and size ratio, height/width ratio, and diameters and angles of surrounding parent and daughter vessels. Univariable and multivariable statistical analyses were performed to determine statistical significance. In multivariable analysis, presence of a daughter dome, aspect ratio, and larger flow angle were significantly associated with rupture status. We also introduced two new variables, diameter size ratio and parent-daughter angle ratio, which were both significantly inversely associated with ruptured basilar tip aneurysms. Notably, multivariable analyses also showed that larger diameter size ratio was associated with higher Hunt-Hess score while smaller flow angle was associated with higher Fisher grade. These easily measurable parameters, including a new parameter that is unlikely to be affected by the formation of the aneurysm, could aid in screening strategies in high-risk patients with basilar tip aneurysms. One should note, however, that the changes in parameters related to aneurysm morphology may be secondary to aneurysm rupture rather than causal.


2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Athanasios K. Petridis ◽  
Marian Suresh ◽  
Jan F. Cornelius ◽  
Angelo Tortora ◽  
Hans Jakob Steiger ◽  
...  

Black blood magnetic resonance imaging (MRI)is a promising imaging tool in predicting aneurysm rupture. Could it be also valuable in evaluating the treatment effect of endovascular and conservative treated aneurysms? Two patients were treated with stent and coil and one with Aspirine (ASS). Correlation of treatment response and contrast enhancement of the aneurysm wall is examined. In the first case stenting failed to treat the aneurysm and contrast enhancement in the wall did never subside during follow up black blood MRI. In the second case the aneurysm responded well to stenting and decreased in size, which was correlating significantly with attenuation of contrast enhancement in black blood MRI. In the third case the aneurysm responded to ASS treatment by decreasing in size as shown in follow up MR-angiography and the contrast enhancement in its wall decreased after 8 months of therapy. Black blood MRI seems to be a promising tool not only in predicting aneurysms at risk of rupture, but also in observing treatment responses after endovascular procedures or even Aspirine administration. When contrast enhancement decreases, aneurysm treatment seems to be successful as can be shown in decreasing size in the follow up angiography.


2010 ◽  
Vol 3 (11) ◽  
pp. 1127-1135 ◽  
Author(s):  
Jin Hur ◽  
Jaeseok Park ◽  
Young Jin Kim ◽  
Hye-Jeong Lee ◽  
Hyo Sup Shim ◽  
...  

2010 ◽  
Vol 31 (3) ◽  
pp. 766-766 ◽  
Author(s):  
David A. Steinman ◽  
Luca Antiga ◽  
Bruce A. Wasserman

2016 ◽  
Vol 34 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Chengcheng Zhu ◽  
Henrik Haraldsson ◽  
Farshid Faraji ◽  
Christopher Owens ◽  
Warren Gasper ◽  
...  

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Athanasios K. Petridis ◽  
Maxine Dibue-Adjei ◽  
Jan F. Cornelius ◽  
Marian Preetham Suresh ◽  
Lan Li ◽  
...  

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Athanasios K. Petridis ◽  
Marian P. Suresh ◽  
Jan F. Cornelius ◽  
Richard Bostelmann ◽  
Maxine Dibué-Adjei ◽  
...  

2018 ◽  
Vol 56 (08) ◽  
pp. e312-e313
Author(s):  
I Mohr ◽  
M Vogeler ◽  
J Pfeiffenberger ◽  
D Sprengel ◽  
M Klauss ◽  
...  

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