scholarly journals Gastric schwannoma: a case report

2016 ◽  
Vol 6 (4) ◽  
Author(s):  
Hayfa Romdhane ◽  
Myriam Cheikh ◽  
Zeineb Mzoughi ◽  
Sana Ben Slama ◽  
Rym Ennaifer ◽  
...  
Keyword(s):  
Epigastric Pain ◽  
Submucosal Tumor ◽  
Muscularis Propria ◽  
Partial Gastrectomy ◽  
Gastric Antrum ◽  
Submucosal Tumors ◽  
Gastric Schwannoma ◽  
One Year ◽  
Immunohistochemical Studies ◽  
Enhanced Computed Tomography

Schwannomas are generally benign, slow growing tumors. They are rarely observed in the gastrointestinal tract with the most common site being the stomach. These tumors are usually asymptomatic. The preoperative diagnosis <em>via</em> endoscopy is a challenging issue due to the difficulty of differentiation from other submucosal tumors. A 54-year-old woman presented with epigastric pain persisting for the last 10 months. Upper endoscopy revealed an elevated submucosal mass of the gastric antrum. The overlying mucosa was normal. Biopsy specimens yielded only unspecific signs of mild inactive chronic inflammation. Endoscopic ultrasound examination noted a hypoechoic homogeneous mass lesion located in the gastric antrum. The mass appeared to arise from the muscularis propria, and there was no perigastric lymphadenopathy. A contrast-enhanced computed tomography scan identified a homogeneous round mass and arising from the antrum of the stomach. Submucosal tumor was suspected and surgical intervention was recommended. The patient underwent an elective laparoscopic partial gastrectomy. The histopathologic features and immunohistochemical-staining pattern were consistent with a benign gastric schwannoma. Our patient shows no recurrence with a follow-up of one year. The definitive diagnosis of gastric schwannomas requires immunohistochemical studies. Complete margin negative surgical resection, as in this case, is the curative treatment of choice. The clinical course is generally benign.

Endoscopic ultrasound to support the diagnosis of submucosal tumors in the upper gastrointestinal tract

2019 ◽  
pp. 14-20
Author(s):  
Thanh Long Nguyen ◽  
Van Huy Tran
Keyword(s):  
Gastrointestinal Tract ◽  
Endoscopic Ultrasound ◽  
Epigastric Pain ◽  
Submucosal Tumor ◽  
Muscularis Propria ◽  
Doppler Signal ◽  
Upper Gastrointestinal Tract ◽  
Muscularis Mucosa ◽  
Submucosal Tumors ◽  
Upper Gastrointestinal

Background and Objectives: Submucosal tumors are generally discovered accidentally. Endoscopic ultrasound is a valuable technique in the diagonsis and management of submucosal tumors, however, there is still little research about the role of endoscopic ultrasound in diagnosing this pathology in Viet Nam. The purpose of this study was to research about endoscopic ultrasound to support the diagnosis of submucosal tumors in the upper gastrointestinal tract. Subjects and methods: This is a cross sectional study on 76 patients were diagnosed submucosal tumors of the upper gastrointestinal tract by endoscopic ultrasound at the Gastrointestinal Endoscopy Center, Hue University of Medicine and Pharmacy Hospital from May 2017 to July 2019. Results: In 76 patients, epigastric pain was most common (57.9%), followed by nausea or vomiting (15.8%); and asymptomatic (39.5%). Submucosal tumors located in the stomach (44.7%), esophagus (40.8%) and duodenum (14.5%). The overlying mucosa: 88.2% with the smooth mucosa, 9.2% with the umbilication (9.2%) and 2.6% with the mucosal ulceration. Mean size was 14.6 ± 9.1 mm. The muscularis mucosa was 47.4%, the submucosa was 13.2%, the muscularis propria was 32.9%. 61.8% with hypoechoic; 5.3% with hyperechoic; 22.4% with anechoic and 10.5% with mixed echoic. 82.9% with homogeneous tumor and 17.1% with heterogeneous tumor. All tumors have a smooth margin. 5.3% with positive Doppler signal and 94.7% with negative Doppler signal. Conclusion: Endoscopic ultrasound can provide information about size, location, structure, margin, Doppler signal and this is a highly valuable technique in the diagnosis of submucosal tumors of the upper gastrointestinal tract. Key words: Submucosal Tumor (SMT), Endoscopic Ultrasound, GastroIntestinal Stromal Tumor

scholarly journals Gastric Schwannoma: A Postoperative Surprise A Case Report.

2014 ◽  
Vol 1 (1) ◽  
pp. 23-25
Author(s):  
Abdelmounaim Ait ALi ◽  
Mohamed Essarghini ◽  
Abderzak Hajjouji ◽  
Khalid Sair
Keyword(s):  
Case Report ◽  
Clinical Case ◽  
Submucosal Tumor ◽  
S100 Protein ◽  
Partial Gastrectomy ◽  
Definitive Diagnosis ◽  
Resected Specimen ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Slow Growing

Gastric Schwannoma is a rare, slow-growing, and clinically non-specific submucosal tumor, originating from Schwann cells with excellent prognosis after surgical resection. We report a clinical case of a patient presented with gastric schwannoma revealed by non-specific gastric signs and of which the definitive diagnosis is done through immunohistochemistry of the resected specimen, showing strong S100 protein positivity. The evolution is favorable after a partial gastrectomy with a decline of two years. Through this case, we are trying to trace the rarity, strong similarities with gastric stromal tumors and especially, the weak index of suspicion for this diagnosis.

scholarly journals Eosinophil granuloma due to parasite treated by laparoscopic and endoscopic cooperative surgery: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Toshikatsu Tsuji ◽  
Noriyuki Inaki
Keyword(s):  
Malignant Disease ◽  
Histopathological Examination ◽  
Epigastric Pain ◽  
Submucosal Tumor ◽  
Eosinophilic Granuloma ◽  
Parasitic Infection ◽  
Partial Gastrectomy ◽  
Gastric Body ◽  
Upper Gastrointestinal Endoscopy ◽  
Undifferentiated Cancer

Abstract Background Gastric eosinophilic granuloma caused by parasitic infection is rare. It is often suspected to be a malignant disease and it is difficult to diagnose. We successfully diagnosed and removed a gastric eosinophilic granuloma using laparoscopic and endoscopic cooperative surgery (LECS). Case presentation A 35-year-old woman visited our hospital because of epigastric pain. Upper gastrointestinal endoscopy revealed a 15 mm submucosal tumor (SMT) with changes in the folds, such as enlargement and convergence, located in the greater curvature of the lower gastric body. Computed tomography (CT) showed a dense, nonenhanced area of 15 mm at the same site. SMT was suspected, but undifferentiated cancer could not be excluded. We performed laparoscopic partial gastrectomy using LECS for resection biopsy. Histopathological examination showed an SMT 8 × 8 × 5 mm in size with an unclear boundary and necrosed insects at the core of the tumor. There was marked eosinophilic infiltration around the area. The diagnosis was gastric granuloma caused by parasitic infection. Conclusions It is difficult to differentiate gastric eosinophilic granuloma caused by parasitic infection from malignant disease. In this case, LECS is considered a minimally invasive and useful procedure.

scholarly journals Gastric Ganglioneuroblastoma in an Elder Man: A Case Report and Literature Review

2021 ◽  
Author(s):  
xuetong jiang ◽  
Jianqiang Wu ◽  
Feng Su ◽  
Hailong Huang ◽  
Yang Ding ◽  
...  
Keyword(s):  
Treatment Guidelines ◽  
Submucosal Tumor ◽  
Gastrointestinal Surgery ◽  
Muscularis Propria ◽  
Laparoscopic Approach ◽  
Gastric Antrum ◽  
Arterial Phase ◽  
Tissue Mass ◽  
Abdomen Ct

Abstract Background: GNB is a moderate tumor of sympathetic origin, which is considered a disease of children with the majority of cases less than five years old and it rarely occurs in adults. There are no treatment guidelines for adults GNB. Here, we reported a rare case of adult gastric GNB, and was resected completely by laparoscopic approach.Case presentation:A 73-year-old man presented with dull pain in the upper abdomen along with abdominal distension for one month. Gastroscopy examination revealed chronic gastritis and submucosal tumor of gastric antrum. Endoscopic ultrasonography showed a hypoechoic mass in gastric antrum arising from the muscularis propria. Combined with the characteristics of gastroscope and ultrasound , the mass was suspected as gastrointestinal stromal tumor. Abdomen CT scan of revealed irregular soft tissue mass in gastric antrum with heterogeneous enhancement in arterial phase, and gastric cancer was suspected.The patient was addressed to the department of gastrointestinal surgery. The mass was completely resected in laparoscopic surgery. Histopathology reported that the mass contained differentiation neuroblasts, mature ganglion cells and ganglioneuromatisis component. Immunohistochemical staining revealed tumor cells were immunoreactive for CD56, Syn, S100 , while negative for CK, CD117, DOG-1, CgA. The pathological diagnosis was GNBi and the patient was staged as stage I. The patient received no adjuvant chemotherapy or radiotherapy.Until his one-year follow-up, the patient was doing well and without any signs of recurrence.Conclusion:Although the rarity of gastric GNB as a primary site of origin, it should be considered in the differential diagnosis of gastric masses in adult. Radical surgery is sufficient for the treatment of GNBi and long-term follow-up should be performed.

scholarly journals Appendicitis with submucosal fecalith mimicking a submucosal tumor: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Tomoaki Bekki ◽  
Toshikatsu Fukuda ◽  
Toshiyuki Moriuchi ◽  
Yosuke Namba ◽  
Sho Okimoto ◽  
...  
Keyword(s):  
Submucosal Tumor ◽  
Lower Abdominal Pain ◽  
Case Presentation ◽  
Submucosal Tumors ◽  
Protein Levels ◽  
Reactive Protein ◽  
Contrast Enhanced ◽  
Enhanced Computed Tomography ◽  
Laparoscopic Assisted ◽  
Contrast Enhanced Computed Tomography

Abstract Background Submucosal fecalith(s) mimicking submucosal tumors of the gastrointestinal lumen are rare. Moreover, accurate preoperative diagnosis of these entities is exceedingly difficult, and the mechanism(s) of their formation remains unclear. Case presentation A 40-year-old woman visited the authors’ hospital due to lower abdominal pain and diarrhea. She had previously been treated for endometriosis. Laboratory investigation revealed increased C-reactive protein levels. Abdominal contrast-enhanced computed tomography revealed thickening of the appendix wall and dilation of the small intestine. The patient was diagnosed with paralytic ileus caused by appendicitis, and interval appendectomy was scheduled. She underwent laparoscopic-assisted appendectomy after conservative treatment. Partial cecal resection was selected due to the presence of an elastic mass in the cecum. The final pathological diagnosis was submucosal fecalith, not submucosal tumor. On day 5, the patient was discharged without any postoperative complications. Conclusions In cases of appendicitis with fecalith(s) that appear as submucosal tumor(s) on colonoscopy, submucosal fecalith mimicking submucosal tumor should be considered in the differential diagnosis.

scholarly journals Gastric Schwannoma: A Rare but Important Differential Diagnosis of a Gastric Submucosal Mass

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
William Yoon ◽  
Kari Paulson ◽  
Paul Mazzara ◽  
Sweety Nagori ◽  
Mohammed Barawi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Surgical Resection ◽  
Treatment Options ◽  
Partial Gastrectomy ◽  
Preoperative Imaging ◽  
Mesenchymal Tumors ◽  
Gastric Schwannoma ◽  
Gastric Mass ◽  
Submucosal Mass ◽  
Slow Growing

Schwannomas are generally slow growing asymptomatic neoplasms that rarely occur in the GI tract. However, if found, the most common site is the stomach. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, and 60–70% of them occur in the stomach. Owing to their typical presentation as submucosal neoplasms, gastric schwannomas and GISTs appear grossly similar. Accordingly, the differential diagnosis for a gastric submucosal mass should include gastric schwannomas. Furthermore, GI schwannomas are benign neoplasms with excellent prognosis after surgical resection, whereas 10–30% of GISTs have malignant behavior. Hence, it is important to distinguish gastric schwannomas from GISTs to make an accurate diagnosis to optimally guide treatment options. Nevertheless, owing to the paucity of gastric schwannomas, the index of suspicion for this diagnosis is low. We report a rare case of gastric schwannoma in 53-year-old woman who underwent laparoscopic partial gastrectomy under the suspicion of a GIST preoperatively but confirmed to have a gastric schwannoma postoperatively. This case underscores the importance of including gastric schwannomas in the differential diagnosis when preoperative imaging studies reveal a submucosal, exophytic gastric mass. For a gastric schwannoma, complete margin negative surgical resection is the curative treatment of choice.

Clinical outcomes of laparoscopic partial gastrectomy for gastric submucosal tumors

2014 ◽  
Vol 8 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Masashi Hirota ◽  
Kiyokazu Nakajima ◽  
Yasuhiro Miyazaki ◽  
Tsuyoshi Takahashi ◽  
Yukinori Kurokawa ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Partial Gastrectomy ◽  
Submucosal Tumors ◽  
Gastric Submucosal Tumors

DEAFNESS FOLLOWING EPIDEMIC PAROTITIS (MUMPS)

PEDIATRICS ◽  
1949 ◽  
Vol 3 (2) ◽  
pp. 177-180
Author(s):  
ROLAND B. SCOTT ◽  
ROBERT P. CRAWFORD
Keyword(s):  
Epigastric Pain ◽  
Past History ◽  
Female Child ◽  
Impaired Hearing ◽  
Parotid Glands ◽  
Ataxic Gait ◽  
Negro Female ◽  
Pediatric Service ◽  
One Year ◽  
Epidemic Parotitis

COMPLICATIONS of epidemic parotitis are unusual before puberty. One of the least commonly reported complications in childhood is deafness. We wish to report such a case and briefly review part of the literature on the subject. [SEE TABLE I and II IN SOURCE PDF]. Case Report E.J., a 10-year-old Negro female, was admitted to the medical pediatric service because of deafness. She was born after a normal gestation and delivery. She walked at 11 mo., talked at one year of age. She had attained Grade IV in school. Her past history included uncomplicated pertussis, uncomplicated measles, frequent colds, and occasional attacks of sore throat. Mother and father were living and well. There was no family history of syphilis or tuberculosis. The present illness began two weeks previously with swelling of both parotid glands. Seven days later she complained of severe epigastric pain. This pain subsided by the next day when the patient vomited twice. Until this time hearing had been apparently normal. Impaired hearing was first noted eight days after the onset of swelling of the parotid glands, and gradually became worse until the patient could not hear the radio and responded only to loud speech. Subsequently, deafness became total and complete. The child complained of tinnitus with the early onset of deafness; and three days later, on getting out of bed, felt weak and had an ataxic gait. As represented in Table I, four siblings developed uncomplicated clinical epidemic parotitis at about the same time as this patient. Physical examination showed a tall, thin, poorly nourished female child, apparently deaf. Temperature was 37.2° C., pulse 108/mm., and BP 110/70 mm.Hg. The epitrochlear, cervical, and submandibular lymph nodes were slightly enlarged. The left parotid gland was slightly enlarged.

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