scholarly journals Leiomyoma of the seminal vesicle: a rare case

2013 ◽  
Vol 3 (2) ◽  
pp. 32 ◽  
Author(s):  
Aftab S. Shaikh ◽  
Girish D. Bakhshi ◽  
Arshad S. Khan ◽  
Nilofar M. Jamadar ◽  
Aravind Kotresh Nirmala ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Urinary Bladder ◽  
Seminal Vesicle ◽  
Bladder Outlet Obstruction ◽  
Rare Case ◽  
Outlet Obstruction ◽  
Benign Tumors ◽  
Review Of Literature ◽  
Elderly Male

Leiomyomas though common benign tumors of smooth muscle cells are extremely rare in the male genitourinary tract. We present a case of an elderly male who presented with complaints suggestive of urinary bladder outlet obstruction since 1 year. His evaluation showed it due to a tumour arising from the left seminal vesicle. Excision of the tumor was done which was diagnosed on histopathology as leiomyoma. A brief case report and review of literature is being presented.

A RARE CASE OF MATURE CYSTIC TERATOMA OF THE URINARY BLADDER

2021 ◽  
pp. 65-66
Author(s):  
Sweta Krishnan ◽  
Aishwerya Singh
Keyword(s):  
Case Report ◽  
Urinary Bladder ◽  
Rare Case ◽  
Cell Layer ◽  
Histopathological Examination ◽  
Multimodality Imaging ◽  
Correct Diagnosis ◽  
Cystic Teratoma ◽  
Benign Tumors ◽  
Rare Site

Introduction: Mature cystic teratomas or dermoid cysts are benign “tumors” which arise from more than one germ cell layer. These occur most commonly in the ovaries. Urinary bladder is an extremely rare site. Only few cases of urinary bladder dermoid cysts have been documented in the literature. Case report: We present a rare case in which a 29-year-old female patient presented with hematuria, passage of hairs in urine and painful micturition. Urinary bladder dermoid cyst along with vesicular calculus was diagnosed on imaging and cystoscopy and conrmed after surgery by histopathological examination. Conclusion: Bladder dermoids mimic bladder calculus and neoplastic mass lesion both clinically and radiologically. Correct diagnosis can be achieved by multimodality imaging, cystoscopy and conrmed on histopathology.

scholarly journals Bladder outlet obstruction triggers neural plasticity in sensory pathways and contributes to impaired sensitivity in erectile dysfunction

2013 ◽  
Vol 304 (10) ◽  
pp. R837-R845 ◽  
Author(s):  
Anna P. Malykhina ◽  
Qi Lei ◽  
Shaohua Chang ◽  
Xiao-Qing Pan ◽  
Antonio N. Villamor ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Erectile Dysfunction ◽  
Urinary Bladder ◽  
Bladder Neck ◽  
Bladder Outlet Obstruction ◽  
Corpus Cavernosum ◽  
Outlet Obstruction ◽  
Nerve Damage ◽  
Sensory Innervation ◽  
Sensory Neuropeptides

Lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are common problems in aging males worldwide. The objective of this work was to evaluate the effects of bladder neck nerve damage induced by partial bladder outlet obstruction (PBOO) on sensory innervation of the corpus cavernosum (CC) and CC smooth muscle (CCSM) using a rat model of PBOO induced by a partial ligation of the bladder neck. Retrograde labeling technique was used to label dorsal root ganglion (DRG) neurons that innervate the urinary bladder and CC. Contractility and relaxation of the CCSM was studied in vitro, and expression of nitric oxide synthase (NOS) was evaluated by Western blotting. Concentration of the sensory neuropeptides substance P (SP) and calcitonin gene-related peptide was measured by ELISA. Partial obstruction of the bladder neck caused a significant hypertrophy of the urinary bladders (2.5-fold increase at 2 wk). Analysis of L6-S2 DRG sections determined that sensory ganglia received input from both the urinary bladder and CC with 5–7% of all neurons double labeled from both organs. The contractile responses of CC muscle strips to KCl and phenylephrine were decreased after PBOO, followed by a reduced relaxation response to nitroprusside. A significant decrease in neuronal NOS expression, but not in endothelial NOS or protein kinase G (PKG-1), was detected in the CCSM of the obstructed animals. Additionally, PBOO caused some impairment to sensory nerves as evidenced by a fivefold downregulation of SP in the CC ( P ≤ 0.001). Our results provide evidence that PBOO leads to the impairment of bladder neck afferent innervation followed by a decrease in CCSM relaxation, downregulation of nNOS expression, and reduced content of sensory neuropeptides in the CC smooth muscle. These results suggest that nerve damage in PBOO may contribute to LUTS-ED comorbidity and trigger secondary changes in the contraction/relaxation mechanisms of CCSM.

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