scholarly journals Primary renal synovial sarcoma

2012 ◽  
Vol 2 (2) ◽  
pp. 44 ◽  
Author(s):  
Girish D. Bakhshi ◽  
Arshad S. Khan ◽  
Aftab S. Shaikh ◽  
Mohammad Ashraf A. Khan ◽  
Mohammad Adil A. Khan ◽  
...  
Keyword(s):  
Synovial Sarcoma ◽  
Poor Prognosis ◽  
Spindle Cell ◽  
Review Of Literature ◽  
Soft Tissue Tumours ◽  
Renal Tumours ◽  
Spindle Cell Tumours ◽  
Synovial Sarcomas ◽  
Sarcoma Patient

Primary Renal Sarcoma is rare tumor comprising only 1% of all renal tumours. Synovial sarcomas are generally deep-seated tumors arising in the proximity of large joints of adolescents and young adults and account for 5-10% of all soft tissue tumours. Primary synovial sarcoma of kidney is rare and has poor prognosis. It can only be diagnosed by immunohistochemistry. It should be considered as a differential in sarcomatoid and spindle cell tumours. We present a case of 33-year-old female, who underwent left sided radical nephrectomy for renal tumour. Histopathology and genetic analysis diagnosed it to be primary renal synovial sarcoma. Patient underwent radiation therapy and 2 years follow up is uneventful. A brief case report with review of literature is presented.

Monophasic spindle cell myxoid synovial sarcoma of the hand: promising results with marginal resection

2021 ◽  
Vol 14 (1) ◽  
pp. e238366
Author(s):  
Sandeep Vijayan ◽  
Afsal P Mohammed ◽  
Mahesh Suresh Kulkarni ◽  
Sharath Kumar Rao
Keyword(s):  
Synovial Sarcoma ◽  
Elderly Woman ◽  
Spindle Cell ◽  
Normal Function ◽  
Malignant Neoplasms ◽  
High Incidence ◽  
Male Preponderance ◽  
Synovial Sarcomas ◽  
Prompt Diagnosis

Synovial sarcomas are deep-seated, genetically distinct, malignant neoplasms seen in young adults, with a male preponderance. They have unusual clinical and pathological presentation and mimic many other sarcomas and carcinomas, making the diagnosis quite challenging. Although four variants are identified, occurrence in the hand is extremely rare and leads to significant morbidity. There is a high incidence of local recurrence and distant metastasis within the first 2 years. We report the case of an elderly woman with monophasic spindle cell synovial sarcoma who presented with painless swelling in her palm and underwent local excision of the neoplasm. At 2-year follow-up, she remains totally asymptomatic with normal function of the hand. We also attempt to give an overview about monophasic spindle cell synovial sarcoma with the differentials, which would help surgeons in prompt diagnosis and appropriate management.

scholarly journals Mediastinal Synovial Sarcoma: A Case Report and Literature Review

2003 ◽  
Vol 10 (7) ◽  
pp. 393-395 ◽  
Author(s):  
Linda SL Cheng ◽  
Gary MK Tse ◽  
Wilson WL Li ◽  
TW Lee ◽  
Anthony PC Yim
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Literature Review ◽  
Synovial Sarcoma ◽  
Spindle Cell ◽  
Diagnosis And Treatment ◽  
Soft Tissue Tumours ◽  
Unusual Location ◽  
Synovial Sarcomas ◽  
Proper Diagnosis

Synovial sarcomas are uncommon soft tissue tumours. Immunohistochemistry and cytogenetic techniques are essential for proper diagnosis and differentiation from other spindle cell neoplasms. A case of mediastinal synovial sarcoma is described, of which the unusual location, diagnosis and treatment form the basis of this report.

Inflammatory Myofibroblastic Tumour in Antimesenteric Border of Descending Colon of Children: A Case Report

2015 ◽  
Vol 3 (1) ◽  
pp. 47-50
Author(s):  
Shahnoor Islam ◽  
AKM Amirul Morshed ◽  
Afiqul Islam
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Inflammatory Myofibroblastic Tumour ◽  
Pathological Findings ◽  
Soft Tissue Lesion ◽  
Soft Tissue Tumours ◽  
Inflammatory Pseudotumour ◽  
Erythrocyte Sedimentation ◽  
Antimesenteric Border

Inflammatory myofibroblastic tumour (IMT) occurring at intraabdominal sites in children has rarely been described. Inflammatory pseudotumour is a soft tissue lesion that may be confused with a sarcoma. It is abbreviated as IMT. Inflammatory myofibroblastic tumour, also known as soft tissue tumours, atypical fibromyxoid tumours, pseudosarcomatous fibromyxoid tumour, plasma cell granuloma, pseudosarcomatous myofibrotic proliferation, post-operative spindle cell nodules. In this paper, we describe a case of inflammatory myofibroblastic tumour (IMT) with an unusual constellation of clinical, pathological findings. A 10-year-old girl had an 7-cm intraabdominal mass accompanied by severe anemia, fever, constipation, weight loss, thrombocytosis, elevated erythrocyte sedimentation rate. Laparotomy was performed. The final pathologic diagnosis was IMT. At the most recent follow up (12months) after excision of the tumour, the patient was symptom-free and there was no evidence of tumour recurrence.J. Paediatr. Surg. Bangladesh 3(1): 47-50, 2012 (January)

scholarly journals A Case of Giant Primary Pleuropulmonary Synovial Sarcoma

2020 ◽  
pp. 1-4
Author(s):  
Wickii T. Vigneswaran ◽  
Brittany C. Fields ◽  
Vijayalakshmi Ananthanarayanan ◽  
Wickii T. Vigneswaran
Keyword(s):  
Synovial Sarcoma ◽  
Soft Tissue Sarcomas ◽  
Extrapleural Pneumonectomy ◽  
Ct Guided ◽  
Prosthetic Reconstruction ◽  
Pathologic Features ◽  
Synovial Sarcomas ◽  
Primary Pulmonary Synovial Sarcoma ◽  
Rare Group

Synovial sarcomas represent an extremely rare subtype of an already rare group of malignancies, soft tissue sarcomas. Among these, primary pulmonary synovial sarcomas comprise an even smaller number, though they have become more frequently reported in the literature. This case report details a case of giant primary pulmonary synovial sarcoma in a 44-year-old male patient who presented with left-sided chest pain and shortness of breath and was found to have a large left-sided pleural effusion. No malignant cells were demonstrated on cytology of pleural fluid after thoracentesis; however, CT-guided needle biopsy of pleural nodules seen on imaging demonstrated pathologic features consistent with monophasic type synovial sarcoma. He was treated with neoadjuvant chemotherapy with minimal response; thus, he was referred for surgical management. A left extrapleural pneumonectomy with resection of the left hemi-diaphragm and Gore-Tex prosthetic reconstruction was performed. Imaging at six-month follow-up demonstrated a new nodule in the contralateral lung, suggestive of metastasis at that time and the patient later developed ascites at nine months, consistent with further intra-abdominal metastasis. Perhaps early diagnosis and aggressive multimodality therapy may have a place in the treatment of this aggressive disease.

Primary ovarian synovial sarcoma

2021 ◽  
Vol 14 (11) ◽  
pp. e244756
Author(s):  
Muhammad Amin ur Rahman ◽  
Khalid Al Wadi ◽  
Al Nuqaydan ◽  
Raghad Tallab
Keyword(s):  
Differential Diagnosis ◽  
Synovial Sarcoma ◽  
Molecular Pathology ◽  
Genital Tract ◽  
Spindle Cell ◽  
Female Genital Tract ◽  
Rare Occurrence ◽  
Spindle Cell Tumours ◽  
Spindle Cell Tumour ◽  
Female Genital

Synovial sarcoma (SS) has a rare occurrence in the female genital tract. Only three prior reports of primary ovarian sarcoma could be retrieved after a thorough literature review. We are reporting a case of primary ovarian SS in a young woman. The tumour showed monophasic spindle cell morphology, and there was a wide list of differential diagnosis to consider. We confirmed the diagnosis by cytogenetics Flourescent Insitu Hybridisation (FISH) technique to identify the classical translocation. The diagnosis of this disease can be challenging especially if the tumour is of monophasic type. Morphology and immunohistochemistry are not enough to confirm the diagnosis in many cases. A confirmatory molecular pathology test is paramount. We have discussed the differential diagnosis of spindle cell tumours in ovary. We suggest that SS should be in the differential diagnoses when facing any atypical spindle cell tumour in the ovary. Molecular pathology techniques can help to confirm the diagnosis.

scholarly journals Manifestation of Pleomorphic Undifferentiated Aortic Sarcoma with Splenic Infarction: A Case Report

2020 ◽  
Vol 13 (2) ◽  
pp. 1002-1005
Author(s):  
Varun Kaushal ◽  
Behzad Amoozgar ◽  
Nabonita Barua ◽  
Shankar Chhetri ◽  
Bhaveshkumar Garsondiya
Keyword(s):  
Poor Prognosis ◽  
Spindle Cell ◽  
Tumor Resection ◽  
Splenic Infarction ◽  
Spindle Cell Sarcoma ◽  
Shortness Of Breath ◽  
Major Vein ◽  
Aortic Sarcoma ◽  
Ct And Mri

Aortic spindle cell sarcoma is a rare neoplasm with poor prognosis that is often found incidentally due to its adverse effects. CT and MRI with contrast are useful imaging modalities, but a tissue biopsy is the gold standard for diagnosis. Tumor resection is the ultimate treatment followed by chemotherapy. Our case was an adult female who presented mainly for shortness of breath, and further imaging workup demonstrated a soft tumor juxtaposed to a major vein with compressive effect. The patient’s tumor was resected, and the pathology result confirmed undifferentiated aortic sarcoma. The patient’s condition improved and she was discharged with outpatient oncology follow-up and possible treatment.

Ultrastructural Features of a Poorly Differentiated Neoplasm Resembling Synovial Sarcoma

1977 ◽  
Vol 35 ◽  
pp. 526-527
Author(s):  
P. K. Simons
Keyword(s):  
Fine Structure ◽  
Light Microscopy ◽  
Synovial Sarcoma ◽  
Spindle Cell ◽  
White Male ◽  
Biphasic Pattern ◽  
Malignant Mesenchymal Tumor ◽  
Synovial Sarcomas ◽  
Poorly Differentiated ◽  
Histologic Differentiation

Synovial sarcoma is a malignant mesenchymal tumor most commonly occurring in the extremities, but is occasionally seen in the trunk, head, and neck regions. The well developed lesion exhibits a distinct biphasic histologic morphology consisting of a spindle cell fibrosarcomatous stroma and epithelial-lined pseudoacinar structures with an associated mucopolysaccharide secretion. The presence of this biphasic pattern is dependent upon the degree of histologic differentiation. Few studies of the fine structure of synovial sarcomas are available and none of the literature has been concerned with these neoplasms occurring in the less common areas. The ultrastructural features of a tumor classified as a poorly differentiated synovial sarcoma are presented.A mass of irregularly shaped, cerebreform tissue was surgically removed from the left side of the neck of a 61 year old white male. The majority of the tissue was fixed in neutral buffered formalin and prepared for light microscopy.

Intraneural Synovial Sarcoma of the Median Nerve in a 15-Year-Old Male: A Case Report and Review of Literature

Hand ◽  
2021 ◽  
pp. 155894472097513
Author(s):  
Arthur Samia ◽  
Joshua Scarcella ◽  
Richard Zeri ◽  
Yifan Guo
Keyword(s):  
Median Nerve ◽  
Synovial Sarcoma ◽  
Thenar Eminence ◽  
Right Hand ◽  
History Of ◽  
Synovial Sarcomas ◽  
Poorly Differentiated ◽  
Web Space ◽  
The Right

There have been 8 synovial sarcomas of the median nerve reported. We report a case of a 15-year-old male with synovial sarcoma of the right-hand median nerve. Patient presented with a 2-month history of enlarging mass at the base of the right thenar eminence associated with numbness in the median nerve distribution. Physical examination revealed a soft mass over the thenar eminence and paresthesia in the median nerve distribution. He underwent excision of the tumor, which revealed a well-encapsulated lesion encompassing the median nerve, involving the first, second, and radial aspect of the third web space as well as recurrent branches of the median nerve. Following excision of the tumor, a thorough metastatic workup was negative for metastatic disease. He was staged as III, T2b, N0, M0—poorly differentiated monophasic synovial sarcoma of the right median nerve. Postoperatively the patient was started on chemotherapy and radiation. Intraneural synovial sarcoma is extremely rare. Our case is the youngest with the longest follow-up. He is currently at a status of 3 years posttreatment with no signs of recurrence and excellent use of his right hand. This case is of particular interest due to the rarity of the disease along with this being the best outcome reported in the literature to-date.

Tonsillar leiomyoma

1987 ◽  
Vol 101 (6) ◽  
pp. 619-623 ◽  
Author(s):  
E. Greenberg ◽  
A. Shupak ◽  
Judith Kelner ◽  
W. S. Meyer
Keyword(s):  
Smooth Muscle ◽  
Spindle Cell ◽  
Correct Diagnosis ◽  
Surgical Excision ◽  
Mitotic Figure ◽  
First Case ◽  
Spindle Cell Tumours ◽  
Benign Leiomyoma ◽  
Histologic Types

AbstractTumors of smooth muscle origin are rare in the oral cavity. To date, only eighty-three cases of oral leiomyomas have been reported. A first case of tonsillar leiomyoma in a 73-year-old male is presented. The theories of origin and the various histologic types of oral leiomyomas are discussed. Leiomyoma can easily be confused with other spindle-cell tumours. Special stains are necessary to reach a correct diagnosis. It is sometimes difficult to differentiate benign leiomyoma from malignant leiomyosarcoma. The use of mitotic figure count to indicate malignant behaviour is not always reliable. The need for wide surgical excision of the tumour, complete sectioning and examination of the specimen and meticulous follow-up of the patient for evidence of recurrence are emphasized.

scholarly journals Synovial sarcoma of the hand-wrist: a case report and review of the literature

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Serenella Serinelli ◽  
Lorenzo Gitto ◽  
Daniel J. Zaccarini
Keyword(s):  
Literature Review ◽  
Synovial Sarcoma ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Caucasian Woman ◽  
Review Of The Literature ◽  
Case Presentation ◽  
Synovial Sarcomas ◽  
Uncommon Case

Abstract Background Synovial sarcomas are infrequent malignant tumors occurring mostly in adolescents and young adults. The occurrence of synovial sarcoma in the hand-wrist area is rare (4 to 8.5% of all synovial sarcomas in different studies). Case presentation This report documents an uncommon case of synovial sarcoma occurring in the hand-wrist of a 69-year-old Caucasian woman. She was subsequently treated with surgical excision and radiotherapy without recurrence after follow up. Conclusions This paper aims to characterize the demographic, pathologic, and clinical features with a literature review. The present literature review confirms that hand-wrist synovial sarcomas are more frequent among males and subjects 10 to 40 years old. Most cases in this location are usually not larger than 5 cm in size. The five-year survival rate is higher than that reported in a previous review on hand synovial sarcomas, and this suggests an improved survival in recent decades.

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