Potential Role of Epstein-Barr Virus in Juvenile Rheumatoid Arthritis

2012 ◽  
Vol 19 (2) ◽  
pp. 65
Author(s):  
Kyung-Sue Shin
1982 ◽  
Vol 25 (8) ◽  
pp. 959-965 ◽  
Author(s):  
Sherman Fong ◽  
John J. Miller ◽  
Terry L. Moore ◽  
Constantine D. Tsoukas ◽  
John H. Vaughan ◽  
...  

2019 ◽  
Vol 15 (24) ◽  
pp. 2873-2885 ◽  
Author(s):  
Mohammad Farahmand ◽  
Seyed Hamidreza Monavari ◽  
Zabihollah Shoja ◽  
Hadi Ghaffari ◽  
Mehdi Tavakoli ◽  
...  

Despite the numerous publications regarding the role of Epstein–Barr virus (EBV) in breast cancer development, the topic has still remained controversial. The aim of the meta-analysis was to estimate the overall prevalence of EBV in the breast cancer population, and to investigate the association between EBV and breast cancer risk. The overall prevalence of EBV was calculated 26.37% (95% CI: 22–31%) from the 44 included studies. Meta-analysis of 30 case–control studies showed that the pooled association between EBV and risk of breast cancer is odds ratio 4.74 (95% CI: 2.92–7.69; Z = 6.30; p < 0.0001). Our analyses indicate a strong statistical relationship between EBV infection and risk of breast cancer, suggesting a potential role of EBV infection in the development of breast cancer.


2020 ◽  
Vol 8 (10) ◽  
pp. 1459
Author(s):  
Marco Bo ◽  
Seyedesomaye Jasemi ◽  
Giuseppe Uras ◽  
Gian Luca Erre ◽  
Giuseppe Passiu ◽  
...  

Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease characterized by chronic erosive polyarthritis. A complex interaction between a favorable genetic background, and the presence of a specific immune response against a broad-spectrum of environmental factors seems to play a role in determining susceptibility to RA. Among different pathogens, mycobacteria (including Mycobacterium avium subspecies paratuberculosis, MAP), and Epstein–Barr virus (EBV), have extensively been proposed to promote specific cellular and humoral response in susceptible individuals, by activating pathways linked to RA development. In this review, we discuss the available experimental and clinical evidence on the interplay between mycobacterial and EBV infections, and the development of the immune dysregulation in RA.


1987 ◽  
Vol 13 (2) ◽  
pp. 275-292
Author(s):  
Robert I. Fox ◽  
Todd Chilton ◽  
Susan Scott ◽  
Laurie Benton ◽  
Francis V. Howell ◽  
...  

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