scholarly journals Two-dimensional Echocardiographic Assessment of Myocardial Strain: Important Echocardiographic Parameter Readily Useful in Clinical Field

2019 ◽  
Vol 49 (10) ◽  
pp. 908 ◽  
Author(s):  
Jae-Hyeong Park
1986 ◽  
Vol 111 (4) ◽  
pp. 714-720 ◽  
Author(s):  
Thomas Ryan ◽  
Olivera Petrovic ◽  
William F. Armstrong ◽  
James C. Dillon ◽  
Harvey Feigenbaum

1982 ◽  
Vol 50 (6) ◽  
pp. 1368-1375 ◽  
Author(s):  
Satoshi Hiraishi ◽  
Thomas G. Disessa ◽  
Jay M. Jarmakani ◽  
Toshio Nakanishi ◽  
Josephine B. Isabel-Jones ◽  
...  

2001 ◽  
Vol 280 (4) ◽  
pp. H1729-H1735 ◽  
Author(s):  
Kotaro Suehiro ◽  
Shin Takuma ◽  
Carol Cardinale ◽  
Takeshi Hozumi ◽  
Juichiro Shimizu ◽  
...  

Murine models of cardiac disease are becoming an important tool for studying pathophysiological processes. Development of methods to accurately assess ventricular function are therefore important. The purpose of this study was to evaluate the feasibility of echocardiographic assessment of segmental wall motion abnormalities in a murine model of myocardial infarction. Two-dimensional contrast (C+) and noncontrast (C−) echocardiography were performed in 76 awake mice 2 days before and 2 days after left coronary ligation. The short-axis images obtained with two-dimensional echocardiography and corresponding postmortem cross-sectional histological samples stained with Evans blue dye were each divided into 16 segments, and all matched segments were examined for correlation between wall motion abnormalities and myocardial hypoperfusion. With the use of contrast enhancement, the number of visualized segments was significantly increased (base: C− 86%, C+ 98%; midpapillary: C− 57%, C+ 89%; apex: C− 30%, C+ 74%). Agreement between echocardiographically assessed regional wall motion abnormalities and pathologically determined hypoperfusion in basal, midpapillary, and apical levels were 90%, 93%, and 93%, respectively. Agreement between echocardiographically normal wall motion and pathologically normal findings in basal, midpapillary, and apical levels were 99%, 88%, and 71%, respectively. Thus echocardiographic assessment of segmental wall motion in awake mice was feasible and the accuracy was improved with the use of a contrast agent.


Sign in / Sign up

Export Citation Format

Share Document