scholarly journals Diffuse Long Coronary Artery Disease is Still an Obstacle for Percutaneous Coronary Intervention in the Second-Generation Drug-Eluting Stent Era?

2019 ◽  
Vol 49 (8) ◽  
pp. 721 ◽  
Author(s):  
Pyung Chun Oh ◽  
Seung Hwan Han
Keyword(s):  
Coronary Artery Disease ◽  
Percutaneous Coronary Intervention ◽  
Coronary Artery ◽  
Second Generation ◽  
Coronary Intervention ◽  
Drug Eluting Stent ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
Artery Disease

scholarly journals Drug-eluting balloon: is it useful?

2020 ◽  
Vol 72 (1) ◽  
Author(s):  
Sidhi Laksono ◽  
Budhi Setianto ◽  
Steven Philip Surya
Keyword(s):  
Coronary Artery Disease ◽  
Percutaneous Coronary Intervention ◽  
Coronary Artery ◽  
Coronary Intervention ◽  
Drug Eluting Stent ◽  
Main Body ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
Artery Disease ◽  
Drug Eluting Balloon

Abstract Background Coronary artery disease is one of the major issues in the medical world around the globe. The prevalence tends to increase. The use of coronary intervention is one of the ways often used in the management of coronary artery disease due to its satisfying result from earlier studies. Nowadays, there are several different techniques in coronary intervention: balloon vs stent. Main body The stent-based vascular interventions are increasingly being used over balloon-based coronary intervention. However, revascularization intervention using stent often have undesirable long-term effects compared to balloon. Besides, stent-based interventions are also considered more expensive, use more complicated techniques, and use more drug regimens. On the other hand, percutaneous coronary intervention techniques using balloons coated by anti-proliferation drugs have begun to be glimpsed by many interventionists. Studies have found many benefits that cannot be given by stent-based intervention therapy. Conclusions Angioplasty using percutaneous coronary intervention techniques reveals satisfying result compared to conservative medical treatment. The indication and technique of percutaneous coronary intervention is still evolving until now. Currently, percutaneous coronary intervention using stent, either bare-metal stent or drug-eluting stent, is preferred by interventionist. Nevertheless, recent clinical trial favors the using of drug-eluting balloon for percutaneous coronary intervention in terms of both clinical outcome and complication in several scenarios.

scholarly journals Back to the future: DCB use instead of DES for the treatment of complex, native coronary artery disease

2021 ◽  
Vol 23 (Supplement_E) ◽  
pp. E63-E67
Author(s):  
Bernardo Cortese ◽  
Erick Sanchez-Jimenez
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Relevant Literature ◽  
Coronary Intervention ◽  
Drug Eluting Stent ◽  
Stent Restenosis ◽  
Well Design ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
Artery Disease

Abstract The increasing complexity of coronary artery lesions in patients with significant co-morbidities and the need for revascularization, but with the ineligibility for surgical approach, has turned the percutaneous coronary intervention a challenging task, especially in a setting in which short- and long-term complications after drug-eluting stent implantation are high. Drug-coated balloons (DCBs) have become an important tool to replace stent placement in specific situations such as small coronary artery disease and in-stent restenosis. Although preliminary data of DCB use in complex lesions is promising, the available data are still limited. Therefore, in this article, we review the most recent and relevant literature about the use of DCB in native vessel disease and in complex anatomies/patients, and pretend to justify the necessity to develop well design trials about the use of this therapy in such settings, also thinking at DCBs as a complementary tool to drug-eluting stents.

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