Acute Aortic Dissection: Population-Based Incidence Compared With Degenerative Aortic Aneurysm Rupture

2004 ◽  
Vol 79 (2) ◽  
pp. 176-180 ◽  
Author(s):  
W. Darrin Clouse ◽  
John W. Hallett ◽  
Hartzell V. Schaff ◽  
Peter C. Spittell ◽  
Charles M. Rowland ◽  
...  
Keyword(s):  
Aortic Aneurysm ◽  
Aortic Dissection ◽  
Acute Aortic Dissection ◽  
Population Based ◽  
Aneurysm Rupture

scholarly journals Aorto-Cutaneous Fistula and False Aneurysm of the Ascending Aorta Five Years after its Prosthetic Replacement for Stanford Type A Acute Aortic Dissection

Aorta ◽  
2017 ◽  
Vol 05 (02) ◽  
pp. 57-60
Author(s):  
Pierre Demondion ◽  
Dorian Verscheure ◽  
Pascal Leprince
Keyword(s):  
Aortic Dissection ◽  
Carotid Arteries ◽  
Acute Aortic Dissection ◽  
False Aneurysm ◽  
Type A ◽  
Aneurysm Rupture ◽  
Ascending Aorta ◽  
Cutaneous Fistula ◽  
The Right ◽  
Selective Cannulation

AbstractAorto-cutaneous fistula and false aneurysm of the ascending aorta in patients who previously underwent Stanford Type A acute aortic dissection are rare and severe complications. Surgical correction remains a demanding challenge. In a case of false aneurysm rupture during redo sternotomy, selective cannulation of the right axillary and left carotid arteries allowed an efficient method of cerebral perfusion.

Usefulness of Suita score to predict deaths from aortic aneurysm rupture and aortic dissection in general population

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
Y Otaki ◽  
T.W Watanabe ◽  
T.K Konta ◽  
M.W Watanabe ◽  
K.A Asahi ◽  
...  
Keyword(s):  
Heart Disease ◽  
Aortic Aneurysm ◽  
General Population ◽  
Aortic Dissection ◽  
Ischemic Heart Disease ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Aneurysm Rupture ◽  
Ischemic Heart ◽  
Framingham Risk

Abstract Background Deaths from aortic aneurysm rupture and aortic dissection are the major causes of sudden death in Japan. Suita score developed in Japan, as well as Framingham risk score, is reportedly associated with ischemic heart disease. However, it remains undetermined whether Suita score is associated with aortic aneurysm rupture and aortic dissection deaths in general population. Purpose To examine whether Suita score could predict aortic aneurysm rupture and aortic dissection deaths in general population. Methods and results We used a database of 534,414 subjects (age 40–75 years) who participated in the annual “Specific Health Check and Guidance in Japan” check-up between 2008 and 2013. The univariate and multivariate Cox proportional hazard regression analyses demonstrated that Suita score was associated with both deaths from aortic aneurysm rupture and aortic dissection after adjustment for confounding risk factors. The C indices in Suita score for aortic aneurysm rupture deaths, aortic dissection deaths and ischemic heart disease deaths were 0.8295, 0.6689, and 0.7039, respectively. The C indices in Suita score to predict aortic aneurysm rupture deaths and aortic dissection deaths were significantly greater than those in Framingham risk score. Conclusion Suita score was superior to Framingham risk score and a feasible marker for aortic aneurysm rupture and aortic dissection deaths in general population, indicating that it could serve as an identification of high-risk subjects for aortic aneurysmal rupture and aortic dissection as well as ischemic heart disease. Funding Acknowledgement Type of funding source: None

A Case of Combined Acute Aortic Dissection and Abdominal Aortic Aneurysm with Hemolysis.

2002 ◽  
Vol 31 (3) ◽  
pp. 227-229
Author(s):  
Etsuro Suenaga ◽  
Kazuhisa Rikitake ◽  
Ryo Shiraishi ◽  
Tsuyoshi Itoh
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Aortic Dissection ◽  
Acute Aortic Dissection ◽  
Abdominal Aortic

scholarly journals Aortic wall thickness in patients with ascending aortic aneurysm versus acute aortic dissection

2015 ◽  
Vol 49 (3) ◽  
pp. 756-762 ◽  
Author(s):  
Joeri Van Puyvelde ◽  
Eric Verbeken ◽  
Peter Verbrugghe ◽  
Paul Herijgers ◽  
Bart Meuris
Keyword(s):  
Aortic Aneurysm ◽  
Aortic Dissection ◽  
Wall Thickness ◽  
Aortic Wall ◽  
Acute Aortic Dissection ◽  
Ascending Aortic Aneurysm ◽  
Aortic Wall Thickness

Acute Aortic Dissection Involving a Fusiform Abdominal Aortic Aneurysm

1999 ◽  
Vol 33 (3) ◽  
pp. 341-345
Author(s):  
Paul E. Y. Van Schil ◽  
Inez E. R. Rodrigus ◽  
Luc R. D. Haenen ◽  
Filip Van den Brande ◽  
Rudolphe G. M. T. Vanmaele ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Aortic Dissection ◽  
Acute Aortic Dissection ◽  
Abdominal Aortic

scholarly journals Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome

2021 ◽  
Author(s):  
Cristina I. Caescu ◽  
Jens Hansen ◽  
Brittany Crockett ◽  
Wenzhen Xiao ◽  
Pauline Arnaud ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Aortic Aneurysm ◽  
Aortic Dissection ◽  
Marfan Syndrome ◽  
Thoracic Aortic Aneurysm ◽  
Acute Aortic Dissection ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Aortic Disease ◽  
Computational Analyses

Objective: Despite considerable research, the goal of finding nonsurgical remedies against thoracic aortic aneurysm and acute aortic dissection remains elusive. We sought to identify a novel aortic protein kinase that can be pharmacologically targeted to mitigate aneurysmal disease in a well-established mouse model of early-onset progressively severe Marfan syndrome (MFS). Approach and Results: Computational analyses of transcriptomic data derived from the ascending aorta of MFS mice predicted a probable association between thoracic aortic aneurysm and acute aortic dissection development and the multifunctional, stress-activated HIPK2 (homeodomain-interacting protein kinase 2). Consistent with this prediction, Hipk2 gene inactivation significantly extended the survival of MFS mice by slowing aneurysm growth and delaying transmural rupture. HIPK2 also ranked among the top predicted protein kinases in computational analyses of genes differentially expressed in the dilated aorta of 3 MFS patients, which strengthened the clinical relevance of the experimental finding. Additional in silico analyses of the human and mouse data sets identified the TGF (transforming growth factor)-β/Smad3 signaling pathway as a potential target of HIPK2 in the MFS aorta. Chronic treatment of MFS mice with an allosteric inhibitor of HIPK2-mediated stimulation of Smad3 signaling validated this prediction by mitigating thoracic aortic aneurysm and acute aortic dissection pathology and partially improving aortic material stiffness. Conclusions: HIPK2 is a previously unrecognized determinant of aneurysmal disease and an attractive new target for antithoracic aortic aneurysm and acute aortic dissection multidrug therapy.

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