Association of Cardiovascular Risk Factors to Aortic Valve Calcification as Quantified by Electron Beam Computed Tomography

2004 ◽  
Vol 79 (10) ◽  
pp. 1242-1246 ◽  
Author(s):  
Karsten Pohle ◽  
Merle Otte ◽  
Ralph Mäffert ◽  
Dieter Ropers ◽  
Michael Schmid ◽  
...  
Keyword(s):  
Risk Factors ◽  
Computed Tomography ◽  
Electron Beam ◽  
Cardiovascular Risk ◽  
Aortic Valve ◽  
Cardiovascular Risk Factors ◽  
Electron Beam Computed Tomography ◽  
Aortic Valve Calcification ◽  
Valve Calcification

scholarly journals Evaluation and Clinical Implications of Aortic Valve Calcification Measured by Electron-Beam Computed Tomography

Circulation ◽  
2004 ◽  
Vol 110 (3) ◽  
pp. 356-362 ◽  
Author(s):  
David Messika-Zeitoun ◽  
Marie-Christine Aubry ◽  
Delphine Detaint ◽  
Lawrence F. Bielak ◽  
Patricia A. Peyser ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Electron Beam ◽  
Aortic Valve ◽  
Clinical Implications ◽  
Electron Beam Computed Tomography ◽  
Aortic Valve Calcification ◽  
Valve Calcification

Aortic valve calcification: association with bone mineral density and cardiovascular risk factors

2005 ◽  
Vol 16 (6) ◽  
pp. 379-383 ◽  
Author(s):  
Yuksel Aksoy ◽  
Cengiz Yagmur ◽  
Gulacan Ozgun Tekin ◽  
Julide Yagmur ◽  
Ergun Topal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bone Mineral Density ◽  
Cardiovascular Risk ◽  
Aortic Valve ◽  
Cardiovascular Risk Factors ◽  
Bone Mineral ◽  
Aortic Valve Calcification ◽  
Mineral Density ◽  
Valve Calcification

Cross-sectional study of aortic valve calcification and cardiovascular risk factors in older Danish men

Heart ◽  
2021 ◽  
pp. heartjnl-2021-319023
Author(s):  
Lida Khurrami ◽  
Jacob Eifer Møller ◽  
Jes Sanddal Lindholt ◽  
Grazina Urbonaviciene ◽  
Flemming Hald Steffensen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Regression Analysis ◽  
Cardiovascular Risk ◽  
Aortic Valve ◽  
Cardiovascular Risk Factors ◽  
Large Population ◽  
Aortic Valve Calcification ◽  
Cross Sectional ◽  
Valve Calcification ◽  
Link Type

ObjectiveAortic valve calcification (AVC) and coronary artery calcification (CAC) are predictors of cardiovascular disease (CVD), presumably sharing risk factors. Our objectives were to determine the prevalence and extent of AVC in a large population of men aged 60–74 years and to assess the association between AVC and cardiovascular risk factors including CAC and biomarkers.MethodsParticipants from the DANish CArdioVAscular Screening and intervention trial (DANCAVAS) with AVC and CAC scores and without previous valve replacement were included in the study. Calcification scores were calculated on non-contrast CT scans. Cardiovascular risk factors were self-reported, measured or both, and further explored using descriptive and regression analysis for AVC association.Results14 073 men aged 60–74 years were included. The AVC scores ranged from 0 to 9067 AU, with a median AVC of 6 AU (IQR 0–82). In 8156 individuals (58.0%), the AVC score was >0 and 215 (1.5%) had an AVC score ≥1200. In the regression analysis, all cardiovascular risk factors were associated with AVC; however, after inclusion of CAC ≥400, only age (ratio of expected counts (REC) 1.07 (95% CI 1.06 to 1.09)), hypertension (REC 1.24 (95% CI 1.09 to 1.41)), obesity (REC 1.34 (95% CI 1.20 to 1.50)), known CVD (REC 1.16 (95% CI 1.03 to 1.31)) and serum phosphate (REC 2.25 (95% CI 1.66 to 3.10) remained significantly associated, while smoking, diabetes, hyperlipidaemia, estimated glomerular filtration rate and serum calcium were not.ConclusionsAVC was prevalent in the general population of men aged 60–74 years and was significantly associated with all modifiable cardiovascular risk factors, but only selectively after adjustment for CAC ≥400 AU.Trial registration numberNCT03946410 and ISRCTN12157806.

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