scholarly journals Challenges in Interpretation of Thyroid Function Tests in Pregnant Women with Autoimmune Thyroid Disease

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Ulla Feldt-Rasmussen ◽  
Anne-Sofie Bliddal Mortensen ◽  
Åse Krogh Rasmussen ◽  
Malene Boas ◽  
Linda Hilsted ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Function ◽  
Thyroid Diseases ◽  
Interindividual Variation ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Autoimmune Thyroid ◽  
Function Tests ◽  
Serum Tsh ◽  
In Pregnancy

Physiological changes during gestation are important to be aware of in measurement and interpretation of thyroid function tests in women with autoimmune thyroid diseases. Thyroid autoimmune activity is decreasing in pregnancy. Measurement of serum TSH is the first-line screening variable for thyroid dysfunction also in pregnancy. However, using serum TSH for control of treatment of maternal thyroid autoimmunity infers a risk for compromised foetal development. Peripheral thyroid hormone values are highly different among laboratories, and there is a need for laboratory-specific gestational age-related reference ranges. Equally important, the intraindividual variability of the thyroid hormone measurements is much narrower than the interindividual variation (reflecting the reference interval). The best laboratory assessment of thyroid function is a free thyroid hormone estimate combined with TSH. Measurement of antithyroperoxidase and/or TSH receptor antibodies adds to the differential diagnosis of autoimmune and nonautoimmune thyroid diseases.

scholarly journals Changes of Thyroid Function Tests in Pregnancy and Contribution of Trimester Specific Reference Ranges to Diagnosis

2015 ◽  
Vol 35 (1) ◽  
pp. 43-48
Author(s):  
Özlem ÇAKIR MADENCİ ◽  
Nihal YÜCEL ◽  
Lale KÖROĞLU DAĞDELEN ◽  
Gülşen MUTLUOĞLU ◽  
Hasan Emin KAYA ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Specific Reference ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Function Tests ◽  
In Pregnancy

scholarly journals Thyroid function tests and its interpretation

2014 ◽  
Vol 4 (7) ◽  
pp. 584-590 ◽  
Author(s):  
KC Shiva Raj
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Function ◽  
Screening Test ◽  
Thyroid Diseases ◽  
Thyroid Function Tests ◽  
Thyroid Disorder ◽  
Medical Conditions ◽  
Hormone Concentration ◽  
Function Tests ◽  
Thyroid Hormone Concentration

Abstract: Thyroid diseases are among the most prevalent of medical conditions. In the patients with obvious features of hypothyroidism or hyperthyroidism thyroid function tests only confirm the diagnosis. Though TSH is widely used as a screening test in suspicion with thyroid disorder, many times TSH alone may be misleading. In this situation TSH along with T4 and T3 should be performed which will resolve the problem. However, thyroid function tests may not concord with each other. Discordant results between TSH, T4 and T3 may be because of various conditions like subclinical hypo- or hyperthyroidism, non-thyroidal illness, drugs etc. Beside that antibody interference and special condition like pregnancy may alter the thyroid hormone concentration. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10318 Journal of Pathology of Nepal (2014) Vol. 4, 584-590  

scholarly journals DIAGNOSTIC DILEMMA IN DISCORDANT THYROID FUNCTION TESTS DUE TO THYROID HORMONE AUTOANTIBODIES

2017 ◽  
Vol 3 (1) ◽  
pp. e22-e25 ◽  
Author(s):  
Panudda Srichomkwun ◽  
Neal H. Scherberg ◽  
Jasminka Jakšić ◽  
Samuel Refetoff
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Function ◽  
Thyroid Function Tests ◽  
Diagnostic Dilemma ◽  
Thyroid Hormone Autoantibodies ◽  
Function Tests

Young adult reference ranges for thyroid function tests on the Centaur immunoassay analyser

2006 ◽  
Vol 63 (4) ◽  
pp. 163-165 ◽  
Author(s):  
M. Alqahatani ◽  
W. Tamimi ◽  
M Aldaker ◽  
F. Alenzi ◽  
H. Tamim ◽  
...  
Keyword(s):  
Young Adult ◽  
Thyroid Function ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Function Tests

Subclinical hypothyroidism

2011 ◽  
pp. 543-547
Author(s):  
Jayne A. Franklyn
Keyword(s):  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Expert Panel ◽  
Elevated Serum ◽  
Thyroid Stimulating Hormone ◽  
Free Thyroxine ◽  
Thyroid Function Tests ◽  
Free Triiodothyronine ◽  
Function Tests ◽  
Serum Tsh

Subclinical hypothyroidism is defined biochemically as the association of a raised serum thyroid-stimulating hormone (TSH) concentration with normal circulating concentrations of free thyroxine (T4) and free triiodothyronine (T3). The term subclinical hypothyroidism implies that patients should be asymptomatic, although symptoms are difficult to assess, especially in patients in whom thyroid function tests have been checked because of nonspecific complaints such as tiredness. An expert panel has recently classified individuals with subclinical hypothyroidism into two groups (1): (1) those with mildly elevated serum TSH (typically TSH in the range 4.5–10.0 mU/l) and (2) those with more marked TSH elevation (serum TSH >10.0 mU/l).

scholarly journals Trend of lipid and thyroid function tests in adults without overt thyroid diseases: A cohort from Tehran thyroid study

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216389 ◽  
Author(s):  
Salma Ahi ◽  
Atieh Amouzegar ◽  
Safoora Gharibzadeh ◽  
Hossein Delshad ◽  
Maryam Tohidi ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Thyroid Diseases ◽  
Thyroid Function Tests ◽  
Function Tests

EFFECT OF INCREASED IODIDE INTAKE ON THYROID FUNCTION IN SUBJECTS ON CHRONIC LITHIUM THERAPY

1977 ◽  
Vol 84 (2) ◽  
pp. 290-296 ◽  
Author(s):  
S. W. Spaulding ◽  
G. N. Burrow ◽  
J. N. Ramey ◽  
R. K. Donabedian
Keyword(s):  
Thyroid Function ◽  
Potassium Iodide ◽  
Lithium Therapy ◽  
Thyroid Function Tests ◽  
Fourth Patient ◽  
Function Tests ◽  
Before And After ◽  
Serum Tsh

ABSTRACT Thyroid function tests were obtained in 10 patients on chronic lithium therapy before and after the administration of potassium iodide 250 mg q. i. d. Mean serum TSH rose by 8.9 μU/ml and mean serum T3 rose from 70 to 101 ng/dl. Two patients became hypothyroid; a third showed a rise in TSH without any change in T3 or T4. A fourth patient developed hyperthyroidism probably secondary to the Jod-Basedow phenomenon. Pharmacologic doses of iodine should be administered with caution to patients on chronic lithium therapy.

scholarly journals Correction: Trend of lipid and thyroid function tests in adults without overt thyroid diseases: A cohort from Tehran thyroid study

PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0220324
Author(s):  
Salma Ahi ◽  
Atieh Amouzegar ◽  
Safoora Gharibzadeh ◽  
Hossein Delshad ◽  
Maryam Tohidi ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Thyroid Diseases ◽  
Thyroid Function Tests ◽  
Function Tests
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