scholarly journals Improving Prognosis Estimation in Patients with Heart Failure and the Cardiorenal Syndrome

2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Husam M. Abdel-Qadir ◽  
Shaan Chugh ◽  
Douglas S. Lee
Keyword(s):  
Heart Failure ◽  
Renal Dysfunction ◽  
Cardiorenal Syndrome ◽  
Left Ventricular ◽  
High Risk Group ◽  
Future Research ◽  
Research Directions ◽  
Patients With Heart Failure ◽  
Future Research Directions

The coexistence of heart failure and renal dysfunction constitutes the “cardiorenal syndrome” which is increasingly recognized as a marker of poor prognosis. Patients with cardiorenal dysfunction constitute a large and heterogeneous group where individuals can have markedly different outcomes and disease courses. Thus, the determination of prognosis in this high risk group of patients may pose challenges for clinicians and for researchers alike. In this paper, we discuss the cardiorenal syndrome as it pertains to the patient with heart failure and considerations for further refining prognosis and outcomes in patients with heart failure and renal dysfunction. Conventional assessments of left ventricular function, renal clearance, and functional status can be complemented with identification of coexistent comorbidities, medication needs, microalbuminuria, anemia, biomarker levels, and pulmonary pressures to derive additional prognostic data that can aid management and provide future research directions for this challenging patient group.

scholarly journals Chemically modified electrodes with MOFs for the determination of inorganic and organic analytes via voltammetric techniques: a critical review

2019 ◽  
Vol 6 (12) ◽  
pp. 3440-3455 ◽  
Author(s):  
Anastasia D. Pournara ◽  
Georgios D. Tarlas ◽  
Giannis S. Papaefstathiou ◽  
Manolis J. Manos
Keyword(s):  
Modified Electrodes ◽  
Current Status ◽  
Future Research ◽  
Research Directions ◽  
Organic Species ◽  
Chemically Modified ◽  
Voltammetric Techniques ◽  
Future Research Directions ◽  
Organic Analytes

Current status on MOF-modified electrodes for voltammetric analyses of inorganic/organic species is critically discussed. We provide future research directions and specific criteria that MOFs should satisfy prior to their use as electrode modifiers.

scholarly journals Status, issues, and future of computer-aided part orientation for additive manufacturing

2021 ◽  
Author(s):  
Yuchu Qin ◽  
Qunfen Qi ◽  
Peizhi Shi ◽  
Paul J. Scott ◽  
Xiangqian Jiang
Keyword(s):  
Additive Manufacturing ◽  
Objective Function ◽  
Future Research ◽  
Research Directions ◽  
Computer Aided ◽  
Future Research Directions ◽  
The Common ◽  
Part Orientation

AbstractPart orientation is a critical task in the process of additive manufacturing product realisation. Recently, various computer-aided methods for this task have been presented in the literature. The coexistence of different methods generates a series of questions: What are the common characteristics of these methods? What are the specific characteristics of each method? What are the main issues in computer-aided part orientation for additive manufacturing currently? What are the potential research directions in this field in the future? To approach these questions, a review of the existing computer-aided part orientation methods for additive manufacturing is presented in this paper. This review starts with a clarification of a part orientation problem and a classification of the existing methods into two categories according to their process of solving the problem. An overview of the representative methods in each category is then carried out from the aspects of approaches for orientation search, generation, or selection, estimation of build orientation factors, determination of weights of factors, establishment of overall objective function, and demonstration of effectiveness. After that, a discussion about the main issues in computer-aided part orientation for additive manufacturing is documented based on the overview. Finally, a suggestion of some future research directions in this field is reported.

Bank Branch Efficiency with DEA

2015 ◽  
pp. 626-667 ◽  
Author(s):  
Mehmet Hasan Eken ◽  
Süleyman Kale
Keyword(s):  
Future Research ◽  
Extensive Literature ◽  
Data Envelopment ◽  
Literature Analysis ◽  
Research Directions ◽  
Bank Branches ◽  
Improvement Strategies ◽  
Future Research Directions ◽  
Different Dimensions

In this chapter, the extent of inefficiency of bank branches in different dimensions is evaluated with slack-based model of data envelopment analysis. Each efficiency dimension reveals the strengths, weaknesses, and improvement capabilities of branches. Multi-dimensional comparison enables the determination of the overall characteristics and the choice of the improvement strategies accordingly. An extensive literature analysis of bank branches and future research directions is also presented.

scholarly journals Echocardiographic and Hemodynamic Parameters Associated with Diminishing Renal Filtration among Patients with Heart Failure with Preserved Ejection Fraction

2018 ◽  
Vol 9 (2) ◽  
pp. 83-91 ◽  
Author(s):  
Kevin Bryan Lo ◽  
Kene Mezue ◽  
Pradhum Ram ◽  
Abhinav Goyal ◽  
Mahek Shah ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Renal Dysfunction ◽  
Pressure Ratio ◽  
Left Ventricular ◽  
Right Atrial ◽  
Heart Catheterization ◽  
Preserved Ejection Fraction ◽  
Patients With Heart Failure

Background: Renal dysfunction is an important predictor of poor outcomes in patients with heart failure with preserved ejection fraction (HFpEF). Right ventricular (RV) dysfunction is implicated as one of the explanations for worsening renal function in cardiorenal syndrome. Novel right heart catheterization (RHC) parameters such as pulmonary artery pulsatility index (PAPi) and right atrial to pulmonary capillary wedge pressure ratio (RA:PCWP) have been found as predictors of RV dysfunction. However, most studies investigating these parameters have been done in the setting of myocardial infarction or left ventricular assist device implantation, with limited data on these metrics in patients with HFpEF. Objective: The purpose of this study was to determine whether novel RHC parameters such as RA:PCWP and PAPi correlate with long-term renal outcomes among patients with HFpEF. Methods: A retrospective single-center study of adult patients with a documented diagnosis of heart failure who had RHC was performed between January 2006 and December 2010 at Einstein Med ical Center Philadelphia. Selected patients also had a serum B-type natriuretic peptide level ≥100 pg/mL and a PCWP ≥15 mm Hg. Patients with an ejection fraction < 50%, including those with recovered ejection fraction, and end-stage renal disease were excluded. Results: A total of 81 patients with a clinical diagnosis of HFpEF were identified who met the inclusion criteria. On multivariate analysis, after adjusting for age, sex, race, diabetes, hypertension, and cardiac index, PAPi was associated with long-term estimated glomerular filtration rate (eGFR) (β = 3.43, 95% CI = 0.635–6.23, p = 0.017), and RA:PCWP showed a trend towards significance (β = 14.81, 95% CI = –0.096–29.73, p = 0.051). The results were unchanged after further adjustment for eGFR at the time of RHC. Conclusion: Novel hemodynamic indices obtained by RHC may have predictive value for long-term renal dysfunction in patients with HFpEF.

scholarly journals Current Understanding of the Biomechanics of Ventricular Tissues in Heart Failure

2019 ◽  
Vol 7 (1) ◽  
pp. 2 ◽  
Author(s):  
Wenqiang Liu ◽  
Zhijie Wang
Keyword(s):  
Heart Failure ◽  
Mechanical Properties ◽  
Computational Models ◽  
Ventricular Dysfunction ◽  
Important Determinant ◽  
Current Understanding ◽  
Future Research ◽  
Research Directions ◽  
Future Research Directions ◽  
The Common

Heart failure is the leading cause of death worldwide, and the most common cause of heart failure is ventricular dysfunction. It is well known that the ventricles are anisotropic and viscoelastic tissues and their mechanical properties change in diseased states. The tissue mechanical behavior is an important determinant of the function of ventricles. The aim of this paper is to review the current understanding of the biomechanics of ventricular tissues as well as the clinical significance. We present the common methods of the mechanical measurement of ventricles, the known ventricular mechanical properties including the viscoelasticity of the tissue, the existing computational models, and the clinical relevance of the ventricular mechanical properties. Lastly, we suggest some future research directions to elucidate the roles of the ventricular biomechanics in the ventricular dysfunction to inspire new therapies for heart failure patients.

scholarly journals An Application Oriented Scan-to-BIM Framework

2019 ◽  
Vol 11 (3) ◽  
pp. 365 ◽  
Author(s):  
Qian Wang ◽  
Jingjing Guo ◽  
Min-Koo Kim
Keyword(s):  
Construction Industry ◽  
Laser Scanning ◽  
Future Research ◽  
Building Information Modelling ◽  
Research Directions ◽  
Building Information ◽  
Future Research Directions ◽  
Scan Data ◽  
Key Steps

Building information modelling (BIM) has been adopted in the construction industry. The success of BIM implementation relies on the accurate building information stored in BIM models. However, building information in BIM models can be inaccurate, out-of-date, or missing in real-world projects. 3D laser scanning has been leveraged to capture the accurate as-is conditions of buildings and create as-is BIM models of buildings; this is known as the scan-to-BIM process. Although industry practitioners and researchers have implemented and studied the scan-to-BIM process, there is no framework that systematically defines and discusses the key steps and considerations in the process. This study proposes an application-oriented framework for scan-to-BIM, which describes the four major steps of a scan-to-BIM process and their relationships. The framework is oriented towards the specific BIM application to be implemented using the created as-is BIM, and includes four steps: (1) identification of information requirements, (2) determination of required scan data quality, (3) scan data acquisition, and (4) as-is BIM reconstruction. Two illustrative examples are provided to demonstrate the feasibility of the proposed scan-to-BIM framework. Furthermore, future research directions within the scan-to-BIM framework are suggested.

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