scholarly journals What Is the Source of Stereoselectivity in Cyclic Silyl-Protected Glycosyl Donor System?

2014 ◽  
Vol 26 (151) ◽  
pp. 141-143
Author(s):  
Akihiro Imamura
Keyword(s):  
Glycosyl Donor ◽  
Donor System

Towards an unprotected self-activating glycosyl donor system: Bromobutyl glycosides

2002 ◽  
Vol 80 (6) ◽  
pp. 555-558 ◽  
Author(s):  
Benjamin G Davis ◽  
Steven D Wood ◽  
Michael AT Maughan
Keyword(s):  
Glycosyl Donor ◽  
Donor System ◽  
Glycosyl Donors

Bromobutyl mannopyranosides have been successfully used as both protected and unprotected glycosyl donors both with and without the use of an external activator.Key words: glycosylation, unprotected glycosyl donors, oligosaccharides.

scholarly journals A One-Pot Approach to Novel Pyridazine C-Nucleosides

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2341
Author(s):  
Flavio Cermola ◽  
Serena Vella ◽  
Marina DellaGreca ◽  
Angela Tuzi ◽  
Maria Rosaria Iesce
Keyword(s):  
Organic Chemistry ◽  
Research Field ◽  
Modified Nucleosides ◽  
Protecting Groups ◽  
Coupling Reactions ◽  
One Pot ◽  
Pharmacological Interest ◽  
Classical Methodology ◽  
Glycosyl Donor ◽  
Neutral Conditions

The synthesis of glycosides and modified nucleosides represents a wide research field in organic chemistry. The classical methodology is based on coupling reactions between a glycosyl donor and an acceptor. An alternative strategy for new C-nucleosides is used in this approach, which consists of modifying a pre-existent furyl aglycone. This approach is applied to obtain novel pyridazine C-nucleosides starting with 2- and 3-(ribofuranosyl)furans. It is based on singlet oxygen [4+2] cycloaddition followed by reduction and hydrazine cyclization under neutral conditions. The mild three-step one-pot procedure leads stereoselectively to novel pyridazine C-nucleosides of pharmacological interest. The use of acetyls as protecting groups provides an elegant direct route to a deprotected new pyridazine C-nucleoside.

scholarly journals Cold-Active β-Galactosidases: Insight into Cold Adaption Mechanisms and Biotechnological Exploitation

Marine Drugs ◽  
2021 ◽  
Vol 19 (1) ◽  
pp. 43
Author(s):  
Marco Mangiagalli ◽  
Marina Lotti
Keyword(s):  
Low Temperature ◽  
Molecular Mechanisms ◽  
Building Blocks ◽  
Cold Active ◽  
Cold Adaption ◽  
Glycosyl Donor ◽  
Pharmaceutical Industries ◽  
Biotechnological Processes ◽  
Hydrolysis Of ◽  
Insight Into

β-galactosidases (EC 3.2.1.23) catalyze the hydrolysis of β-galactosidic bonds in oligosaccharides and, under certain conditions, transfer a sugar moiety from a glycosyl donor to an acceptor. Cold-active β-galactosidases are identified in microorganisms endemic to permanently low-temperature environments. While mesophilic β-galactosidases are broadly studied and employed for biotechnological purposes, the cold-active enzymes are still scarcely explored, although they may prove very useful in biotechnological processes at low temperature. This review covers several issues related to cold-active β-galactosidases, including their classification, structure and molecular mechanisms of cold adaptation. Moreover, their applications are discussed, focusing on the production of lactose-free dairy products as well as on the valorization of cheese whey and the synthesis of glycosyl building blocks for the food, cosmetic and pharmaceutical industries.

Buddhist Business and Benevolence in Leh, Ladakh

2020 ◽  
Vol 27 (1) ◽  
pp. 60-71
Author(s):  
Elizabeth Williams-Oerberg
Keyword(s):  
Financial Support ◽  
Business Owners ◽  
Economic Transformation ◽  
Tourism Industry ◽  
Economic Resources ◽  
Himalayan Region ◽  
Indian Himalayan Region ◽  
Leading Role ◽  
The Social ◽  
Donor System

Due to a burgeoning tourism industry in the Indian Himalayan region of Ladakh, Buddhist monasteries now have lucrative means for generating income through tourism-related business and financial support from international sponsors and local business owners. Where previously Buddhist monasteries were dependent on the donations and labour of the lay community, currently, with the accumulation of surplus wealth, many Buddhist leaders of prominent monasteries have begun flipping this donor system around. Throughout this article, I look at how Buddhist monastic leaders have invested surplus economic resources into philanthropic projects as a way to ‘give back’ to the wider community. I argue that the philanthropic initiatives by Buddhist leaders in Ladakh help to position Buddhist monastics as taking a leading role in the social and economic transformation of the region, thus working to push back against processes of secularization that threaten to decrease the influence of Buddhist monastic institutions.

Phenyl 2,3,4-tri-O-acetyl-1-thio-α-L-rhamnopyranoside: a glycosyl donor

2007 ◽  
Vol 63 (9) ◽  
pp. o3772-o3772
Author(s):  
Yow-Fu Tsai ◽  
Jen-Ta Yang ◽  
Jhy-Der Chen ◽  
Chia-Her Lin
Keyword(s):  
Glycosyl Donor

ChemInform Abstract: Lauryl and Stearyl Thioglycosides: Preparation and Reactivity of the Glycosyl Donor.

ChemInform ◽  
2010 ◽  
Vol 31 (36) ◽  
pp. no-no
Author(s):  
Hideaki Matsui ◽  
Jun-ichi Furukawa ◽  
Takuro Awano ◽  
Norio Nishi ◽  
Nobuo Sakairi
Keyword(s):  
Glycosyl Donor

Synthesis of phenyl 3,4-di-O-benzyl-2,6-dideoxy-3-C-methyl-1-thio-α,β-l-xylo-hexopyranoside. A glycosyl donor for axenose

2000 ◽  
Vol 11 (1) ◽  
pp. 139-149 ◽  
Author(s):  
Garry R Smith ◽  
Frank J Villani ◽  
Luca Failli ◽  
Robert M Giuliano
Keyword(s):  
Glycosyl Donor

Synthesis of a C-7 Pd-glycosyl-donor via the base promoted alkylative CO2 trapping with 2-acetylfuran

2021 ◽  
Vol 54 ◽  
pp. 101774
Author(s):  
Karol R. Francisco ◽  
Yu Li ◽  
Brent Lindquist-Kleissler ◽  
Jiamin Zheng ◽  
Yalan Xing ◽  
...  
Keyword(s):  
Glycosyl Donor

First preparative synthesis of a 3-acetamido-3,6-dideoxy-d-galactopyranose glycosyl donor via intramolecular cyclization of an epoxytrichloroacetimidate

2004 ◽  
Vol 45 (23) ◽  
pp. 4445-4448 ◽  
Author(s):  
Emiliano Bedini ◽  
Alfonso Iadonisi ◽  
Antonella Carabellese ◽  
Michelangelo Parrilli
Keyword(s):  
Intramolecular Cyclization ◽  
Preparative Synthesis ◽  
Glycosyl Donor

scholarly journals Short Synthesis of Idraparinux by Applying a 2-O -Methyl-4,6-O -arylmethylene Thioidoside as a 1,2-trans -α-Selective Glycosyl Donor

2018 ◽  
Vol 2018 (48) ◽  
pp. 6901-6912
Author(s):  
Fruzsina Demeter ◽  
Fanni Veres ◽  
Mihály Herczeg ◽  
Anikó Borbás
Keyword(s):  
Glycosyl Donor ◽  
Short Synthesis
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