scholarly journals Stromal Cell–Mediated Coordination of Immune Cell Recruitment, Retention, and Function in Brain-Adjacent Regions

2021 ◽  
Vol 206 (2) ◽  
pp. 282-291
Author(s):  
Valeria Ramaglia ◽  
Alexandra Florescu ◽  
Michelle Zuo ◽  
Salma Sheikh-Mohamed ◽  
Jennifer L. Gommerman
Keyword(s):  
Stromal Cell ◽  
Immune Cell ◽  
Cell Recruitment ◽  
And Function ◽  
Immune Cell Recruitment

scholarly journals Inflammation in Periodontal Disease: Possible Link to Vascular Disease

2021 ◽  
Vol 11 ◽  
Author(s):  
Oindrila Paul ◽  
Payal Arora ◽  
Michael Mayer ◽  
Shampa Chatterjee
Keyword(s):  
Periodontal Disease ◽  
Bacterial Infections ◽  
Immune Cell ◽  
Epidemiological Data ◽  
Cell Recruitment ◽  
Periodontal Inflammation ◽  
Tissue Healing ◽  
And Function ◽  
Immune Cell Recruitment

Inflammation is a well-organized protective response to pathogens and consists of immune cell recruitment into areas of infection. Inflammation either clears pathogens and gets resolved leading to tissue healing or remains predominantly unresolved triggering pathological processes in organs. Periodontal disease (PD) that is initiated by specific bacteria also triggers production of inflammatory mediators. These processes lead to loss of tissue structure and function. Reactive oxygen species and oxidative stress play a role in susceptibility to periodontal pathogenic bacterial infections. Periodontal inflammation is a risk factor for systemic inflammation and eventually cardiovascular disease (CVD). This review discusses the role of inflammation in PD and its two way association with other health conditions such as diabetes and CVD. Some of the mechanisms underpinning the links between inflammation, diabetes, CVD and PD are also discussed. Finally, we review available epidemiological data and other reports to assess possible links between oral health and CVD.

scholarly journals A Missing Link: Engagements of Dendritic Cells in the Pathogenesis of SARS-CoV-2 Infections

2021 ◽  
Vol 22 (3) ◽  
pp. 1118
Author(s):  
Abdulaziz Alamri ◽  
Derek Fisk ◽  
Deepak Upreti ◽  
Sam K. P. Kung
Keyword(s):  
Dendritic Cells ◽  
Severe Acute Respiratory Syndrome ◽  
Immune Responses ◽  
Immune Cell ◽  
Inflammatory Responses ◽  
Viral Disease ◽  
Cell Recruitment ◽  
Cross Presentation ◽  
Cell Immunity ◽  
Immune Cell Recruitment

Dendritic cells (DC) connect the innate and adaptive arms of the immune system and carry out numerous roles that are significant in the context of viral disease. Their functions include the control of inflammatory responses, the promotion of tolerance, cross-presentation, immune cell recruitment and the production of antiviral cytokines. Based primarily on the available literature that characterizes the behaviour of many DC subsets during Severe acute respiratory syndrome (SARS) and coronavirus disease 2019 (COVID-19), we speculated possible mechanisms through which DC could contribute to COVID-19 immune responses, such as dissemination of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to lymph nodes, mounting dysfunctional inteferon responses and T cell immunity in patients. We highlighted gaps of knowledge in our understanding of DC in COVID-19 pathogenesis and discussed current pre-clinical development of therapies for COVID-19.

scholarly journals Interleukin-17D and Nrf2 mediate initial innate immune cell recruitment and restrict MCMV infection

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Ruth Seelige ◽  
Robert Saddawi-Konefka ◽  
Nicholas M. Adams ◽  
Gaëlle Picarda ◽  
Joseph C. Sun ◽  
...  
Keyword(s):  
Immune Cell ◽  
Innate Immune ◽  
Innate Immune Cell ◽  
Mcmv Infection ◽  
Cell Recruitment ◽  
Immune Cell Recruitment

scholarly journals Non-Coding RNAs in COVID-19: Emerging Insights and Current Questions

2021 ◽  
Vol 7 (3) ◽  
pp. 54
Author(s):  
Tobias Plowman ◽  
Dimitris Lagos
Keyword(s):  
Immune Response ◽  
Severe Acute Respiratory Syndrome ◽  
Immune Cell ◽  
Cytokine Storm ◽  
Cell Recruitment ◽  
Vascular Dysregulation ◽  
Virus Rna ◽  
Growing Body ◽  
Non Coding Rnas ◽  
Immune Cell Recruitment

The highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as the causative agent of coronavirus disease 2019 (COVID-19) in late 2019, igniting an unprecedented pandemic. A mechanistic picture characterising the acute immunopathological disease in severe COVID-19 is developing. Non-coding RNAs (ncRNAs) constitute the transcribed but un-translated portion of the genome and, until recent decades, have been undiscovered or overlooked. A growing body of research continues to demonstrate their interconnected involvement in the immune response to SARS-CoV-2 and COVID-19 development by regulating several of its pathological hallmarks: cytokine storm syndrome, haemostatic alterations, immune cell recruitment, and vascular dysregulation. There is also keen interest in exploring the possibility of host–virus RNA–RNA and RNA–RBP interactions. Here, we discuss and evaluate evidence demonstrating the involvement of short and long ncRNAs in COVID-19 and use this information to propose hypotheses for future mechanistic and clinical studies.

scholarly journals Mesenchymal Cells Hold the Key to Immune Cell Recruitment to and Migration within Melanoma

2013 ◽  
Vol 133 (9) ◽  
pp. 2138-2140
Author(s):  
Kimberley A. Beaumont ◽  
Marcia A. Munoz ◽  
Wolfgang Weninger
Keyword(s):  
Immune Cell ◽  
Mesenchymal Cells ◽  
Cell Recruitment ◽  
And Migration ◽  
Immune Cell Recruitment

Canephron N reduced immune cell recruitment in experimental cystitis

2017 ◽  
Vol 16 (3) ◽  
pp. e230-e231 ◽  
Author(s):  
B. Nausch ◽  
J. Röhrl ◽  
A. Koeberle ◽  
U. Harler ◽  
M. Joannidis ◽  
...  
Keyword(s):  
Immune Cell ◽  
Cell Recruitment ◽  
Immune Cell Recruitment
Sign in / Sign up

Export Citation Format

Share Document