Inhibition of Nitric Oxide Synthase Initiates Relapsing Remitting Experimental Autoimmune Encephalomyelitis in Rats, Yet Nitric Oxide Appears to be Essential for Clinical Expression of Disease

Nikki C. O’Brien; Brett Charlton; William B. Cowden; David O. Willenborg

doi:10.4049/jimmunol.167.10.5904

Inhibition of Nitric Oxide Synthase Initiates Relapsing Remitting Experimental Autoimmune Encephalomyelitis in Rats, Yet Nitric Oxide Appears to be Essential for Clinical Expression of Disease

The Journal of Immunology ◽

10.4049/jimmunol.167.10.5904 ◽

2001 ◽

Vol 167 (10) ◽

pp. 5904-5912 ◽

Cited By ~ 29

Author(s):

Nikki C. O’Brien ◽

Brett Charlton ◽

William B. Cowden ◽

David O. Willenborg

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Clinical Expression ◽

Autoimmune Encephalomyelitis ◽

Relapsing Remitting ◽

Oxide Synthase ◽

Experimental Autoimmune

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Macrolide Antibiotics Aggravate Experimental Autoimmune Encephalomyelitis and Inhibit Inducible Nitric Oxide Synthase

Immunological Investigations ◽

10.1080/08820130903062194 ◽

2009 ◽

Vol 38 (7) ◽

pp. 602-612 ◽

Cited By ~ 8

Author(s):

Dunjing Wang ◽

Zhengqi Lu ◽

Liping Hu ◽

Yuefeng Zhang ◽

Xueqiang Hu

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Macrolide Antibiotics ◽

Autoimmune Encephalomyelitis ◽

Oxide Synthase ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Sodium salicylate-induced amelioration of experimental autoimmune encephalomyelitis in Lewis rats is associated with the suppression of inducible nitric oxide synthase and cyclooxygenases

Neuroscience Letters ◽

10.1016/j.neulet.2003.11.038 ◽

2004 ◽

Vol 356 (2) ◽

pp. 123-126 ◽

Cited By ~ 14

Author(s):

Changjong Moon ◽

Meejung Ahn ◽

Youngheun Jee ◽

Seungdam Heo ◽

Seungjoon Kim ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Sodium Salicylate ◽

Autoimmune Encephalomyelitis ◽

Oxide Synthase ◽

Induced Amelioration ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis

Journal of Neuroscience Research ◽

10.1002/jnr.10139 ◽

2002 ◽

Vol 67 (4) ◽

pp. 461-470 ◽

Cited By ~ 27

Author(s):

Patricia Murphy ◽

Anthony Sharp ◽

Joseph Shin ◽

Vitaliy Gavrilyuk ◽

Cinzia Dello Russo ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Autoimmune Encephalomyelitis ◽

Oxide Synthase ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Bone marrow-derived versus parenchymal sources of inducible nitric oxide synthase in experimental autoimmune encephalomyelitis

Journal of Neuroimmunology ◽

10.1016/j.jneuroim.2004.01.020 ◽

2004 ◽

Vol 150 (1-2) ◽

pp. 70-79 ◽

Cited By ~ 13

Author(s):

Simone P Zehntner ◽

Lyne Bourbonniere ◽

Mina Hassan-Zahraee ◽

Elise Tran ◽

Trevor Owens

Keyword(s):

Nitric Oxide ◽

Bone Marrow ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Autoimmune Encephalomyelitis ◽

Oxide Synthase ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Effect of staphylococcal enterotoxin B injection on the development of experimental autoimmune encephalomyelitis: influence of cytokine and inducible nitric oxide synthase production

Journal of Neuroimmunology ◽

10.1016/s0165-5728(99)00024-7 ◽

1999 ◽

Vol 99 (2) ◽

pp. 157-168 ◽

Cited By ~ 9

Author(s):

Liz Milstein Kuschnaroff ◽

Lut Overbergh ◽

Hassane Sefriouni ◽

Halina Sobis ◽

Michel Vandeputte ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Staphylococcal Enterotoxin B ◽

Autoimmune Encephalomyelitis ◽

Enterotoxin B ◽

Oxide Synthase ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Measurement of Upregulation of Inducible Nitric Oxide Synthase in the Experimental Autoimmune Encephalomyelitis Model Using a Positron Emitting Radiopharmaceutical

Nitric Oxide ◽

10.1006/niox.1997.0120 ◽

1997 ◽

Vol 1 (3) ◽

pp. 263-267 ◽

Cited By ~ 9

Author(s):

Jian Zhang ◽

Anne H. Cross ◽

Timothy J. McCarthy ◽

Michael J. Welch

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Autoimmune Encephalomyelitis ◽

Experimental Autoimmune Encephalomyelitis Model ◽

Oxide Synthase ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis

European Journal of Immunology ◽

10.1002/(sici)1521-4141(199804)28:04<1332::aid-immu1332>3.0.co;2-g ◽

1998 ◽

Vol 28 (4) ◽

pp. 1332-1338 ◽

Cited By ~ 124

Author(s):

Ulrike C. Sahrbacher ◽

Franziska Lechner ◽

Hans-Pietro Eugster ◽

Karl Frei ◽

Hans Lassmann ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Autoimmune Encephalomyelitis ◽

Oxide Synthase ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Enhanced Expression of Constitutive Endothelial Nitric Oxide Synthase by Astrocytes in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis

Immunological Investigations ◽

10.3109/08820139909062271 ◽

1999 ◽

Vol 28 (5-6) ◽

pp. 381-390 ◽

Cited By ~ 2

Author(s):

Taekyun Shin

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Endothelial Nitric Oxide Synthase ◽

Autoimmune Encephalomyelitis ◽

Enhanced Expression ◽

Oxide Synthase ◽

Endothelial Nitric Oxide ◽

Experimental Autoimmune

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Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.

Journal of Clinical Investigation ◽

10.1172/jci117282 ◽

1994 ◽

Vol 93 (6) ◽

pp. 2684-2690 ◽

Cited By ~ 294

Author(s):

A H Cross ◽

T P Misko ◽

R F Lin ◽

W F Hickey ◽

J L Trotter ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Inducible Nitric Oxide Synthase ◽

Autoimmune Encephalomyelitis ◽

Oxide Synthase ◽

Experimental Autoimmune ◽

Inducible Nitric Oxide

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Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis

Journal of Neuroimmunology ◽

10.1016/0165-5728(94)00192-q ◽

1995 ◽

Vol 58 (1) ◽

pp. 81-88 ◽

Cited By ~ 110

Author(s):

J Zielasek

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Experimental Autoimmune Encephalomyelitis ◽

Experimental Autoimmune Neuritis ◽

Autoimmune Encephalomyelitis ◽

Nitric Oxide Synthase Inhibitors ◽

Oxide Synthase ◽

Experimental Autoimmune

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