Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4+ Regulatory T Cells in Tumors from Mice and Humans

Jeremy D. Waight; Shinji Takai; Bo Marelli; Guozhong Qin; Kenneth W. Hance; Dong Zhang; Robert Tighe; Yan Lan; Kin-Ming Lo; Helen Sabzevari; Robert Hofmeister; Nicholas S. Wilson

doi:10.4049/jimmunol.1402725

Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4+ Regulatory T Cells in Tumors from Mice and Humans

The Journal of Immunology ◽

10.4049/jimmunol.1402725 ◽

2014 ◽

Vol 194 (3) ◽

pp. 878-882 ◽

Cited By ~ 33

Author(s):

Jeremy D. Waight ◽

Shinji Takai ◽

Bo Marelli ◽

Guozhong Qin ◽

Kenneth W. Hance ◽

...

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Epigenetic Regulation ◽

Cutting Edge ◽

Stable Population

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Comment on “Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4+ Regulatory T Cells in Tumors from Mice and Humans”

The Journal of Immunology ◽

10.4049/jimmunol.1500248 ◽

2015 ◽

Vol 194 (8) ◽

pp. 3533.1-3533 ◽

Cited By ~ 2

Author(s):

Jochen Huehn ◽

Stefan Floess ◽

Naganari Ohkura ◽

Shimon Sakaguchi

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Epigenetic Regulation ◽

Cutting Edge ◽

Stable Population

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Response to Comment on “Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4+ Regulatory T cells in Tumors from Mice and Humans”

The Journal of Immunology ◽

10.4049/jimmunol.1500367 ◽

2015 ◽

Vol 194 (8) ◽

pp. 3533.2-3534 ◽

Cited By ~ 2

Author(s):

Jeremy D. Waight ◽

Robert Hofmeister ◽

Nicholas S. Wilson

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Epigenetic Regulation ◽

Cutting Edge ◽

Stable Population

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Faculty Opinions recommendation of Cutting edge: CD8+CD122+ regulatory T cells produce IL-10 to suppress IFN-gamma production and proliferation of CD8+ T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1029287.343656 ◽

2005 ◽

Author(s):

Steve Ward

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Cd8 T Cells ◽

Cutting Edge ◽

Ifn Gamma

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Faculty Opinions recommendation of Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1086115.539093 ◽

2007 ◽

Author(s):

Stephen Cobbold

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Th17 Cells ◽

Cutting Edge ◽

Tgf Beta

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Faculty Opinions recommendation of Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1103251.559261 ◽

2008 ◽

Author(s):

Thomas Huenig

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Inflammatory Mediators ◽

Cutting Edge

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Faculty Opinions recommendation of Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732104629.793540536 ◽

2017 ◽

Author(s):

Abhay R Satoskar ◽

Steve Oghumu

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Cutting Edge

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Comment on “Cutting Edge: Depletion of Foxp3+ Cells Leads to Induction of Autoimmunity by Specific Ablation of Regulatory T Cells in Genetically Targeted Mice”

The Journal of Immunology ◽

10.4049/jimmunol.1090014 ◽

2010 ◽

Vol 184 (8) ◽

pp. 4051.1-4051 ◽

Cited By ~ 4

Author(s):

Dominik Wolf ◽

Anna Maria Wolf ◽

Alexandar Tzankov

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Cutting Edge

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Cutting Edge: ICOS-Deficient Regulatory T Cells Display Normal Induction of Il10 but Readily Downregulate Expression of Foxp3

The Journal of Immunology ◽

10.4049/jimmunol.1801266 ◽

2019 ◽

Vol 202 (4) ◽

pp. 1039-1044 ◽

Cited By ~ 18

Author(s):

Ashley E. Landuyt ◽

Barbara J. Klocke ◽

Tyler B. Colvin ◽

Trenton R. Schoeb ◽

Craig L. Maynard

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Cutting Edge

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Cutting Edge: Inhibition of Glycogen Synthase Kinase 3 Activity Induces the Generation and Enhanced Suppressive Function of Human IL-10+ FOXP3+–Induced Regulatory T Cells

The Journal of Immunology ◽

10.4049/jimmunol.2000136 ◽

2020 ◽

Vol 205 (6) ◽

pp. 1497-1502

Author(s):

Hao Cheng ◽

Lingbiao Wang ◽

Biaolong Yang ◽

Dan Li ◽

Xiaoxia Wang ◽

...

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Glycogen Synthase ◽

Cutting Edge ◽

Glycogen Synthase Kinase ◽

Glycogen Synthase Kinase 3 ◽

Suppressive Function

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Cutting Edge: CRISPR-Based Transcriptional Regulators Reveal Transcription-Dependent Establishment of Epigenetic Memory of Foxp3 in Regulatory T Cells

The Journal of Immunology ◽

10.4049/jimmunol.2000537 ◽

2020 ◽

Vol 205 (11) ◽

pp. 2953-2958

Author(s):

James Cameron ◽

Pieter Martino ◽

Lina Nguyen ◽

Xudong Li

Keyword(s):

T Cells ◽

Regulatory T Cells ◽

Transcriptional Regulators ◽

Cutting Edge ◽

Epigenetic Memory

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