scholarly journals TheYersinia pseudotuberculosisOuter Membrane Protein Ail Recruits the Human Complement Regulatory Protein Factor H

2012 ◽  
Vol 189 (7) ◽  
pp. 3593-3599 ◽  
Author(s):  
Derek K. Ho ◽  
Rauna Riva ◽  
Mikael Skurnik ◽  
Seppo Meri
Keyword(s):  
Membrane Protein ◽  
Regulatory Protein ◽  
Factor H ◽  
Human Complement ◽  
Complement Regulatory Protein ◽  
Protein Factor

scholarly journals Deficiency of the Human Complement Regulatory Protein Factor H Associated with Low Levels of Component C9

2008 ◽  
Vol 68 (4) ◽  
pp. 445-455 ◽  
Author(s):  
D. A. Falcão ◽  
E. S. Reis ◽  
D. Paixão-Cavalcante ◽  
M. T. Amano ◽  
M. I. M. V. Delcolli ◽  
...  
Keyword(s):  
Regulatory Protein ◽  
Factor H ◽  
Human Complement ◽  
Complement Regulatory Protein ◽  
Protein Factor ◽  
Low Levels

scholarly journals Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis

2017 ◽  
Vol 199 (11) ◽  
pp. 3821-3827 ◽  
Author(s):  
Sarah J. Kane ◽  
Taylor K. Farley ◽  
Elizabeth O. Gordon ◽  
Joshua Estep ◽  
Heather R. Bender ◽  
...  
Keyword(s):  
Regulatory Protein ◽  
Factor H ◽  
Complement Regulatory Protein ◽  
Protein Factor

Arg127 of complement regulatory protein Factor H is important for its secretion from human fibroblasts

2009 ◽  
Vol 46 (14) ◽  
pp. 2869
Author(s):  
José Antonio Tavares Albuquerque ◽  
Dayseanne Araújo Falcão ◽  
Lourdes Isaac
Keyword(s):  
Human Fibroblasts ◽  
Regulatory Protein ◽  
Factor H ◽  
Complement Regulatory Protein ◽  
Protein Factor

Functional properties of the allotypes of mouse complement regulatory protein, factor H: Difference of compatibility of each allotype with human factor I

1993 ◽  
Vol 30 (9) ◽  
pp. 841-848 ◽  
Author(s):  
Okada Michiyo ◽  
Kojima Ayako ◽  
Takano Hiromi ◽  
Harada Yoshinobu ◽  
Nonaka Mayumi ◽  
...  
Keyword(s):  
Functional Properties ◽  
Human Factor ◽  
Regulatory Protein ◽  
Factor H ◽  
Complement Regulatory Protein ◽  
Factor I ◽  
Protein Factor

scholarly journals The Meningococcal Vaccine Candidate GNA1870 Binds the Complement Regulatory Protein Factor H and Enhances Serum Resistance

2006 ◽  
Vol 177 (1) ◽  
pp. 501-510 ◽  
Author(s):  
Guillermo Madico ◽  
Jo Anne Welsch ◽  
Lisa A. Lewis ◽  
Anne McNaughton ◽  
David H. Perlman ◽  
...  
Keyword(s):  
Vaccine Candidate ◽  
Regulatory Protein ◽  
Factor H ◽  
Serum Resistance ◽  
Meningococcal Vaccine ◽  
Complement Regulatory Protein ◽  
Protein Factor

Arg127 of complement regulatory protein Factor H is responsible for the secretion rate of this protein by human fibroblasts

2010 ◽  
Vol 47 (13) ◽  
pp. 2221-2221
Author(s):  
José Antonio T. Albuquerque ◽  
Marcelo Lamers ◽  
Marinilce Dos Santos ◽  
Lourdes Isaac
Keyword(s):  
Human Fibroblasts ◽  
Regulatory Protein ◽  
Factor H ◽  
Secretion Rate ◽  
Complement Regulatory Protein ◽  
Protein Factor

scholarly journals Human complement factor H deficiency associated with hemolytic uremic syndrome.

1998 ◽  
Vol 9 (12) ◽  
pp. 2318-2326
Author(s):  
N Rougier ◽  
M D Kazatchkine ◽  
J P Rougier ◽  
V Fremeaux-Bacchi ◽  
J Blouin ◽  
...  
Keyword(s):  
Hemolytic Uremic Syndrome ◽  
Regulatory Protein ◽  
Large Deletion ◽  
Factor H ◽  
Pcr Analysis ◽  
Complement Factor ◽  
Human Complement ◽  
Protein Factor ◽  
Factor H Deficiency ◽  
Uremic Syndrome

This study reports on six cases of deficiency in the human complement regulatory protein Factor H (FH) in the context of an acute renal disease. Five of the cases were observed in children presenting with idiopathic hemolytic uremic syndrome (HUS). Two of the children exhibited a homozygous deficiency characterized by the absence of the 150-kD form of Factor H and the presence, upon immunoblotting, of the 42-kD Factor H-like protein 1 (FHL-1) and other FH-related protein (FHR) bands. Southern blot and PCR analysis of DNA of one patient with homozygous deficiency ruled out the presence of a large deletion of the FH gene as the underlying defect for the deficiency. The other four children presented with heterozygous deficiency and exhibited a normal immunoblotting pattern of proteins of the FH family. Factor H deficiency is the only complement deficiency associated with HUS. These observations suggest a role for FH and/or FH receptors in the pathogenesis of idiopathic HUS.

Sign in / Sign up

Export Citation Format

Share Document