scholarly journals The Role of Skin-Derived Dendritic Cells in CD8+ T Cell Priming Following Immunization with Lentivectors

2010 ◽  
Vol 184 (9) ◽  
pp. 4889-4897 ◽  
Author(s):  
Karina Furmanov ◽  
Mazal Elnekave ◽  
Dan Lehmann ◽  
Bjorn E. Clausen ◽  
Darrell N. Kotton ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
T Cell ◽  
Cd8 T Cell ◽  
T Cell Priming

scholarly journals Human conventional CD1c+ Dendritic Cells produce IL-12 and induce potent CD8+ T cell priming

2013 ◽  
Vol 4 ◽  
Author(s):  
Nizzoli Giulia ◽  
Weick Anja ◽  
Krietsch Jana ◽  
Steinfelder Svenja ◽  
Facciotti Federica ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
T Cell ◽  
Cd8 T Cell ◽  
T Cell Priming

A novel regulatory role of gp49B on dendritic cells in T-cell priming

2008 ◽  
Vol 38 (9) ◽  
pp. 2426-2437 ◽  
Author(s):  
Satoshi Kasai ◽  
Masanori Inui ◽  
Kyohei Nakamura ◽  
Yuta Kakizaki ◽  
Shota Endo ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
T Cell ◽  
Regulatory Role ◽  
T Cell Priming

scholarly journals Correction: A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells

2016 ◽  
Vol 12 (7) ◽  
pp. e1005771
Author(s):  
Jonatan Ersching ◽  
Alexandre Salgado Basso ◽  
Vera Lúcia Garcia Calich ◽  
Karina Ramalho Bortoluci ◽  
Maurício M. Rodrigues
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
T Cell ◽  
Cd8 T Cell ◽  
T Cell Priming

scholarly journals Diacylglycerol Lipase-β Is Required for TNF-α Response but Not CD8+ T Cell Priming Capacity of Dendritic Cells

2019 ◽  
Vol 26 (7) ◽  
pp. 1036-1041.e3 ◽  
Author(s):  
Myungsun Shin ◽  
Andrew Buckner ◽  
Jessica Prince ◽  
Timothy N.J. Bullock ◽  
Ku-Lung Hsu
Keyword(s):  
Dendritic Cells ◽  
T Cell ◽  
Cd8 T Cell ◽  
Diacylglycerol Lipase ◽  
Tnf Α ◽  
T Cell Priming

scholarly journals The role of cDC1s in vivo: CD8 T cell priming through cross-presentation

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 98 ◽  
Author(s):  
Derek Theisen ◽  
Kenneth Murphy
Keyword(s):  
Bone Marrow ◽  
Dendritic Cells ◽  
T Cell ◽  
Antigen Processing ◽  
Molecular Mechanisms ◽  
T Cell Responses ◽  
Cd8 T Cell ◽  
Cross Presentation ◽  
Cell Responses

The cDC1 subset of classical dendritic cells is specialized for priming CD8 T cell responses through the process of cross-presentation. The molecular mechanisms of cross-presentation remain incompletely understood because of limited biochemical analysis of rare cDC1 cells, difficulty in their genetic manipulation, and reliance onin vitrosystems based on monocyte- and bone-marrow-derived dendritic cells. This review will discuss cross-presentation from the perspective of studies with monocyte- or bone-marrow-derived dendritic cells while highlighting the need for future work examining cDC1 cells. We then discuss the role of cDC1s as a cellular platform to combine antigen processing for class I and class II MHC presentation to allow the integration of “help” from CD4 T cells during priming of CD8 T cell responses.

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