scholarly journals Usefulness of Sputum Induction with Hypertonic Saline in a Real Clinical Practice for Bacteriological Yields of Active Pulmonary Tuberculosis

2014 ◽  
Vol 76 (4) ◽  
pp. 163 ◽  
Author(s):  
Gil Myeong Seong ◽  
Jaechun Lee ◽  
Jong Hoo Lee ◽  
Jeong Hong Kim ◽  
Miok Kim
Keyword(s):  
Clinical Practice ◽  
Pulmonary Tuberculosis ◽  
Hypertonic Saline ◽  
Sputum Induction ◽  
Active Pulmonary Tuberculosis ◽  
Real Clinical Practice

Differential diagnosis of destructive pulmonary tuberculosis in real clinical practice

2020 ◽  
Author(s):  
Natalya Karpina ◽  
Ruslan Asanov ◽  
Irina Shabalina ◽  
Ekaterina Shishkina ◽  
Atadzhan Ergeshov
Keyword(s):  
Differential Diagnosis ◽  
Clinical Practice ◽  
Pulmonary Tuberculosis ◽  
Real Clinical Practice

scholarly journals Role of induced sputum with hypertonic saline in the early diagnosis of no / inadequate sputum or sputum smear negative suspected cases of pulmonary tuberculosis

2017 ◽  
Vol 5 (11) ◽  
pp. 4761
Author(s):  
Mayank Kapur ◽  
Atul Luhadia ◽  
Shanti Kumar Luhadia
Keyword(s):  
Early Diagnosis ◽  
Pulmonary Tuberculosis ◽  
Hypertonic Saline ◽  
Invasive Procedure ◽  
Induced Sputum ◽  
Sputum Smear ◽  
Sputum Induction ◽  
Pulmonary Tb ◽  
Smear Negative

Background: Pulmonary Tuberculosis is one of the common infections in the world, especially in developing countries like India and is a leading cause of morbidity and mortality worldwide. Therefore, early diagnosis and microbiological confirmation of pulmonary TB is important. This study was done to assess the role of induced sputum with hypertonic saline in suspected pulmonary TB patients who produce no or inadequate sputum or who are sputum for AFB smear negative.Methods: 100 patients with clinical and radiological evidence of pulmonary TB with no or inadequate sputum or who are smear negative with spontaneous sputum were included in the study. Sputum was induced with 5ml of 3% hypertonic saline delivered through nebulizer and then was sent for Ziehl Neelsen staining examination.Results: 96 patients could produce adequate sputum after sputum induction. In 47 patients, sputum for AFB smear was found positive after induction.Conclusions: Sputum induction is a safe, cheap and non-invasive procedure and offers an alternative or additional approach in the diagnosis of sputum smear-negative suspected pulmonary tuberculosis patients and would enhance sensitivity for the diagnosis of tuberculosis. 

scholarly journals Bacteriological analysis of induced sputum for the diagnosis of pulmonary tuberculosis in the clinical practice of a general tertiary hospital

2009 ◽  
Vol 35 (11) ◽  
pp. 1092-1099 ◽  
Author(s):  
Sabrina Bollmann Garcia ◽  
Christiano Perin ◽  
Marcel Muller da Silveira ◽  
Gustavo Vergani ◽  
Sérgio Saldanha Menna-Barreto ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Pulmonary Tuberculosis ◽  
Diagnostic Yield ◽  
Laboratory Data ◽  
Induced Sputum ◽  
Smear Microscopy ◽  
Sputum Induction ◽  
Cross Sectional ◽  
Pulmonary Tb ◽  
Bacteriological Analysis

OBJECTIVE: To determine the diagnostic sensitivity of bacteriological analyses in induced sputum (IS) for the diagnosis of pulmonary tuberculosis (TB) and to identify the clinical characteristics associated with the confirmed diagnosis, as well as to determine the diagnostic yield of bronchoscopy carried out when IS tests negative for AFB in smear microscopy. METHODS: A retrospective, cross-sectional study of patients suspected of having active pulmonary TB and referred to our clinic for sputum induction. We consecutively reviewed the laboratory data of all patients submitted to sputum induction between June of 2003 and January of 2006, as well as their electronic medical records. In addition, the results of the bacteriological analysis of bronchoscopic specimens collected from the patients whose AFB tests were negative in IS were reviewed. RESULTS: Of the 417 patients included in the study, 83 (19.9%) presented IS samples that tested positive for TB (smear microscopy or culture). In the logistic regression analysis, radiological findings of cavitation (OR = 3.8; 95% CI: 1.9-7.6) and of miliary infiltrate (OR = 3.7; 95% CI: 1.6-8.6) showed the strongest association with the diagnosis of pulmonary TB. In 134 patients, bronchoscopy was carried out after negative AFB results in IS and added 25 (64.1%) confirmed diagnoses of pulmonary TB. CONCLUSIONS: In our clinical practice, the frequency of confirmed diagnosis of pulmonary TB using IS (19.9%) was lower than that previously reported in controlled trials. Cavitation and miliary infiltrate increase the diagnostic probability of pulmonary TB using IS. The use of bronchoscopy when IS tests negative for AFB significantly increases sensitivity in the diagnosis of pulmonary TB.

In real clinical practice osteoporosis drugs are taken for a very short period: analysis of persistence in the campania region

2013 ◽  
Author(s):  
Giovanni Iolascon ◽  
Annarita Capaldo ◽  
Valentina Orlando ◽  
Enrica Menditto ◽  
Francesca Gimigliano
Keyword(s):  
Clinical Practice ◽  
Campania Region ◽  
Period Analysis ◽  
Short Period ◽  
Real Clinical Practice
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