scholarly journals An animal model of status epilepticus induced by massed electrical stimulations to the deep prepiriform cortex

2007 ◽  
Vol 119 (1) ◽  
pp. 41-47
Author(s):  
Fumihiko Koyama
Keyword(s):  
Animal Model ◽  
Status Epilepticus

Animal models of status epilepticus and temporal lobe epilepsy: a narrative review

2018 ◽  
Vol 29 (7) ◽  
pp. 757-770 ◽  
Author(s):  
Nikita Nirwan ◽  
Preeti Vyas ◽  
Divya Vohora
Keyword(s):  
Animal Model ◽  
Status Epilepticus ◽  
Animal Models ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Current Literature ◽  
Clinical Characteristics ◽  
Genetic Models ◽  
Suitable Animal Model ◽  
Effective Models

Abstract Temporal lobe epilepsy (TLE) is the chronic and pharmacoresistant form of epilepsy observed in humans. The current literature is insufficient in explicating the comprehensive mechanisms underlying its pathogenesis and advancement. Consequently, the development of a suitable animal model mimicking the clinical characteristics is required. Further, the relevance of status epilepticus (SE) to animal models is dubious. SE occurs rarely in people; most epilepsy patients never experience it. The present review summarizes the established animal models of SE and TLE, along with a brief discussion of the animal models that have the distinctiveness and carries the possibility to be developed as effective models for TLE. The review not only covers the basic requirements, mechanisms, and methods of induction of each model but also focuses upon their major limitations and possible modifications for their future use. A detailed discussion on chemical, electrical, and hypoxic/ischemic models as well as a brief explanation on the genetic models, most of which are characterized by development of SE followed by neurodegeneration, is presented.

scholarly journals An Animal Model of Nonconvulsive Status Epilepticus: A Contribution to Clinical Controversies

Epilepsia ◽  
2008 ◽  
Vol 42 (2) ◽  
pp. 171-180 ◽  
Author(s):  
Pavel Kršek ◽  
Anna Mikulecká ◽  
Rastislav Druga ◽  
Zdeněk Hliňák ◽  
Hana Kubová ◽  
...  
Keyword(s):  
Animal Model ◽  
Status Epilepticus ◽  
Nonconvulsive Status Epilepticus

scholarly journals An Animal Model of Nonconvulsive Status Epilepticus: A Contribution to Clinical Controversies

Epilepsia ◽  
2003 ◽  
Vol 42 ◽  
pp. 171-180
Author(s):  
Pavel Kršek ◽  
Anna Mikulecká ◽  
Rastislav Druga ◽  
Zdeněk Hliňák ◽  
Hana Kubová ◽  
...  
Keyword(s):  
Animal Model ◽  
Status Epilepticus ◽  
Nonconvulsive Status Epilepticus

scholarly journals The evolution of the pilocarpine animal model of status epilepticus

Heliyon ◽  
2020 ◽  
Vol 6 (7) ◽  
pp. e04557
Author(s):  
Iman Imtiyaz Ahmed Juvale ◽  
Ahmad Tarmizi Che Has
Keyword(s):  
Animal Model ◽  
Status Epilepticus
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