NOTES ON PIERIS RAPÆ

1872 ◽  
Vol 4 (6) ◽  
pp. 102-105
Author(s):  
G. J. Bowles
Keyword(s):  
Pieris Rapae ◽  
Recent Introduction ◽  
Yellow Male ◽  
Rapid Dissemination

The April number of the Entomologist contains a commnunication from my esteemed friend Mr. S. H. Scudder, with reference to the yellow male variety of this species. In it he asks several questions which I shall endeavour to answer, adding some other particulars to make my notes as complete as possible.I think that entomologists will agree with me in considering P. rapæas one of the most interesting insects existing on this continent, not only with refercnce to its destructive habits, but also on account of its recent introduction and rapid dissemination over the country.

Identification of a Cotesia species parasitizing on Pieris rapae from Beijing

2013 ◽  
Vol 38 (1) ◽  
pp. 61-63
Author(s):  
Lan-shao YOU ◽  
Ai-ping ZENG ◽  
Li-zhang WEN
Keyword(s):  
Pieris Rapae

Brexit and the English Question

2017 ◽  
Author(s):  
Stephen Tierney
Keyword(s):  
Intergovernmental Relations ◽  
Constitutional Reform ◽  
Coherent System ◽  
Inadequate Response ◽  
Asymmetric System ◽  
Recent Introduction ◽  
The Uk

The chapter examines Brexit and the English question, arguing that Brexit should be understood as a result of the ongoing demotic process in England. As Tierney explains, the UK is an asymmetric system. England alone constitutes population-wise almost four-fifths of the UK. This has influenced devolution: while since the 1990s power has transferred outwards towards the devolved nations, England herself has never received equivalent constitutional autonomy, or recognition, within the UK. Proposals for regional devolution within England, transferring powers to nationwide cities, have also failed. the recent introduction within the House of Common of the principle ‘English Votes for English Laws’—allowing only MPs elected in English constituencies to vote on laws concerning England alone, thus overcoming the well-known West Lothian question—is also an inadequate response to ever-increasing nationalistic views. To address this situation post-Brexit, Tierney concludes that constitutional reform is necessary, entrenching a coherent system of intergovernmental relations.

scholarly journals The Role of Monoclonal Antibodies in Smoldering and Newly Diagnosed Transplant-Eligible Multiple Myeloma

2020 ◽  
Vol 13 (12) ◽  
pp. 451
Author(s):  
Elena Zamagni ◽  
Paola Tacchetti ◽  
Paola Deias ◽  
Francesca Patriarca
Keyword(s):  
Multiple Myeloma ◽  
Monoclonal Antibodies ◽  
Immune System ◽  
Survival Outcomes ◽  
Newly Diagnosed ◽  
Cellular Targets ◽  
Recent Introduction

The recent introduction of monoclonal antibodies (MoAbs), with several cellular targets, such as CD-38 (daratumumab and isatuximab) and SLAM F7 (elotuzumab), differently combined with other classes of agents, has significantly extended the outcomes of patients with multiple myeloma (MM) in different phases of the disease. Initially used in advanced/refractory patients, different MoAbs combination have been introduced in the treatment of newly diagnosed transplant eligible patients (NDTEMM), showing a significant improvement in the depth of the response and in survival outcomes, without a significant price in terms of toxicity. In smoldering MM, MoAbs have been applied, either alone or in combination with other drugs, with the goal of delaying the progression to active MM and restoring the immune system. In this review, we will focus on the main results achieved so far and on the main on-going trials using MoAbs in SMM and NDTEMM.

scholarly journals Disentangling transcriptional responses in plant defense against arthropod herbivores

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alejandro Garcia ◽  
M. Estrella Santamaria ◽  
Isabel Diaz ◽  
Manuel Martinez
Keyword(s):  
Regulatory Networks ◽  
Pieris Rapae ◽  
Meta Analysis ◽  
Plant Response ◽  
Plant Responses ◽  
Transcriptional Responses ◽  
Crop Species ◽  
Physiological Processes ◽  
Meta Analyses ◽  
Plant Herbivore

AbstractThe success in the response of a plant to a pest depends on the regulatory networks that connect plant perception and plant response. Meta-analyses of transcriptomic responses are valuable tools to discover novel mechanisms in the plant/herbivore interplay. Considering the quantity and quality of available transcriptomic analyses, Arabidopsis thaliana was selected to test the ability of comprehensive meta-analyses to disentangle plant responses. The analysis of the transcriptomic data showed a general induction of biological processes commonly associated with the response to herbivory, like jasmonate signaling or glucosinolate biosynthesis. However, an uneven induction of many genes belonging to these biological categories was found, which was likely associated with the particularities of each specific Arabidopsis-herbivore interaction. A thorough analysis of the responses to the lepidopteran Pieris rapae and the spider mite Tetranychus urticae highlighted specificities in the perception and signaling pathways associated with the expression of receptors and transcription factors. This information was translated to a variable alteration of secondary metabolic pathways. In conclusion, transcriptomic meta-analysis has been revealed as a potent way to sort out relevant physiological processes in the plant response to herbivores. Translation of these transcriptomic-based analyses to crop species will permit a more appropriate design of biotechnological programs.

scholarly journals Uptake of biosimilar trastuzumab in Denmark compared with other European countries: a comparative study and discussion of factors influencing implementation and uptake of biosimilars

2021 ◽  
Author(s):  
Samuel Azuz ◽  
Max Newton ◽  
Dorthe Bartels ◽  
Birgitte Klindt Poulsen
Keyword(s):  
Comparative Study ◽  
Market Share ◽  
European Countries ◽  
Sales Volume ◽  
Eu Countries ◽  
Factors Influencing ◽  
European Data ◽  
Similar Strategy ◽  
Rapid Dissemination

Abstract Purpose The aim of this study was to describe the implementation and uptake of biosimilar trastuzumab in Denmark compared with other European countries. Methods European data for usage of trastuzumab was supplied by IQVIA™, using the MIDAS® dataset. A comparison was performed based on market share estimated in sales volume. A separate comparison was undertaken between countries with a full two-fold switch between different biosimilars. Data was collected spanning the time from first registered sales of biosimilar trastuzumab until the 1st quarter of 2020. Results Denmark had the fastest and most thorough uptake of biosimilar trastuzumab compared with other EU countries. After 3 months, the market share of biosimilar trastuzumab had increased to 90% while the second fastest country had a 50% market share after 3 months. Only two other countries had undergone a full second switch between biosimilars, Hungary and Norway. All of the three countries made near complete switches between biosimilars while only Denmark had reduced the use of biooriginator below 10%. Conclusion The implementation of biosimilar trastuzumab in Denmark was rapid and achieved high overall uptake compared with other EU countries. The switch from one biosimilar to another was also achieved quickly and thoroughly. We believe that the rapid dissemination of information and involvement of all stakeholders — administrators, pharmacies, prescribers, nurses, and patients — constitute the backbone of the Danish success. A similar strategy is recommend for biosimilar implementation in other countries.

scholarly journals Conservation: A New Open Access Journal for Rapid Dissemination of the Transdisciplinary Dimensions of Biodiversity Conservation

Conservation ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 17-20
Author(s):  
Antoni Margalida ◽  
Luca Luiselli ◽  
José L. Tella ◽  
Shuqing Zhao
Keyword(s):  
Open Access ◽  
Biodiversity Conservation ◽  
Case Reports ◽  
Digital Publishing ◽  
Open Access Journal ◽  
Research Articles ◽  
Original Research ◽  
Rapid Dissemination

We are pleased to launch the new peer-reviewed open access journal, Conservation, published by MDPI (Multidisciplinary Digital Publishing Institute), which offers an exciting new opportunity to publish comprehensive reviews, original research articles, communications, case reports, letters, commentaries, and other perspectives related to the biological, sociological, ethical, economic, methodological, and other transdisciplinary dimensions of conservation [...]

Commission 6: Astronomical Telegrams: (Telegrammes Astronomiques)

2000 ◽  
Vol 24 (1) ◽  
pp. 378-379
Author(s):  
R. M. West ◽  
B. G. Marsden ◽  
K. Aksnes ◽  
S. Nakano ◽  
E. Roemer ◽  
...  
Keyword(s):  
Central Bureau ◽  
Rapid Dissemination

Throughout the triennium, Commission 6 has interacted with the Central Bureau for Astronomical Telegrams (CBAT), most ably headed by Brian Marsden. As will be seen from his report below, the use by scientists of the Circulars for rapid dissemination of astronomical and related news continues unabated.

The Efficiency of the Greek Lighthouse Network

1998 ◽  
Vol 51 (3) ◽  
pp. 421-429
Author(s):  
Julia Englesou ◽  
Mary Lekakou ◽  
Ernest Tzannatos
Keyword(s):  
Coastal Structures ◽  
Signal Reliability ◽  
Recent Introduction ◽  
Coastal Shipping ◽  
The Many ◽  
High Level

Among the many primary causes which lead to a shipping casualty, those of wrecking, stranding or coming into contact with fixed coastal structures depend (although not exclusively and only under specific conditions of visibility) upon the efficiency of the lighthouse and navigating lights network of a national coastline. The analysis of the shipping casualties involving Greek ships in the Greek seas revealed that, despite the recent introduction of sophisticated navigating aids for the prevention of stranding and contact, the share of the corresponding casualties remains unchanged. It appears that for coastal shipping operations, and in particular for port approaches, the traditional light navigating aids are and will always provide an irreplaceable safety service for navigators. This is mainly attributed to their technological simplicity which offers a high level of signal reliability and friendliness for the navigator.

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