Capping Arterial Sheaths in Patients Undergoing Percutaneous Coronary Intervention: Evidence-Based Practice

2002 ◽  
Vol 22 (3) ◽  
pp. 64-68
Author(s):  
Linda M. Sulzbach-Hoke ◽  
Dorothy Cupich
2016 ◽  
Vol 14 (4) ◽  
pp. 388-393 ◽  
Author(s):  
Shaban Mohammed ◽  
Abdulrahaman Arabi ◽  
Ayman El-Menyar ◽  
Sabir Abdulkarim ◽  
Amer AlJundi ◽  
...  

2020 ◽  
Vol 26 (1) ◽  
pp. 67-74
Author(s):  
Robert N. Kerley ◽  
Gearoid Fitzgerald ◽  
John Joseph Coughlan ◽  
Ciaran Kelly ◽  
Max Waters ◽  
...  

Background: Limited data are available regarding real-world prescribing in patients with an indication for oral anticoagulation (OAT) who undergo percutaneous coronary intervention (PCI). Most current guidelines recommend a period of triple therapy with OAT and dual antiplatelet (DAPT) agents over dual therapy with an OAT and DAPT but the clinical benefit is still unclear giving rise to limited evidence-based recommendations. Aim: To analyze the appropriateness of OAT and anti-platelet strategies post PCI in a real-world cohort of patients in 2 academic teaching hospitals. Methods and Results: In total, 103 patients were retrospectively analyzed. As the initial 3 month stragey, 97 patients (94.2%) received triple therapy, 4 received Dual Therapy (3.9%) and 2 received DAPT (1.9%). Patients with predominant bleeding risk were significantly less likely to receive triple therapy (75% vs. 95.7% vs. 95.8%, P < 0.05). Apixaban was the most common OAT (65.7%) which in most cases was prescribed at an inappropriately reduced dose of 2.5 mg BD (80.4%). The MACE, bleeding and all-cause mortality rates did not differ significantly between groups. Discussion: Our study demonstrates the widespread use of triple therapy for the first 3 months of treatment in 2 Irish academic hospitals. DOACs were prescribed in most cases at reduced doses not currently known to prevent stroke. This study highlights the need for more explicit management algorithms to improve evidence-based management in this area.


2018 ◽  
Vol 10 (2) ◽  
pp. 121-125
Author(s):  
Mohammad Arifur Rahman ◽  
Afzalur Rahman ◽  
Syed Nasir Uddin ◽  
Md AKM Monwarul Islam ◽  
Tariq Ahmed Chowdhury ◽  
...  

Background: Octogenarians are high risk patients and largely under-represented in clinical trials. The use of evidence-based therapy is, therefore, lower in this age group, resulting in a reliance on non-evidence based decision making. The elderly usually have higher prevalence of co morbidities and more often experience complications during and after revascularization procedures.Methods: 212 patients with ischemic heart disease who underwent percutaneous coronary intervention (PCI) were divided into 2 groups according to age: ³80 years (n = 74) and < 80 years (n = 138). Baseline clinical characteristics, indications for coronary intervention, in hospital outcomes and 1 year outcome were obtained. Study endpoint was in hospital outcome (Renal impairment, MI, LVF, emergency revascularization, death) & 1 year follow up for myocardial infarction (MI), repeat revascularization and death.Results: Procedural success (TIMI III) were high in both groups, but still lower in the elderly as compared to younger group (95% vs. 97%, p=0.65).The elderly had higher incidence of post PCI bleeding, contrast induced nephropathy (CIN), MI, left ventricular failure (LVF) and death (9.5% vs.6.1%, 8.2% vs.3.7%, 6.8% vs.5.8%, 9.5% vs. 5.1% and 5.4%vs.3.6%, p=0.07). Whereas emergency revascularization were higher in younger group (5.4% vs. 6.5%, p=0.07). At 1 year MI and death were higher in elderly group (9.5% vs.6.5%, 6.8% vs.6.5% p=0.66), whereas repeat revascularization were higher in younger group (6.8% vs.8%, p= 0.66).Conclusion: Though immediate interventional procedure related complications are more in octogenarians, long term outcomes seem to be promising & comparable with younger counterparts.Cardiovasc. j. 2018; 10(2): 121-125


2015 ◽  
Vol 11 (2) ◽  
pp. 137-146 ◽  
Author(s):  
Steven ES Miner ◽  
Lynne E Nield ◽  
Sylvain Plante ◽  
Lorne Goldman ◽  
Manu Prabhakar ◽  
...  

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