scholarly journals Clinical Evaluation of Laparoscopic Gastrectomy for Gastric Cancer in the Elderly Patients Using POSSUM and E-PASS Scoring System

2016 ◽  
Vol 41 (4) ◽  
pp. 559-566
Author(s):  
Takeshi Matsutani ◽  
Itsuro Fujita ◽  
Yoshikazu Kanazawa ◽  
Nobutoshi Hagiwara ◽  
Tsutomu Nomura ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Clinical Evaluation ◽  
Laparoscopic Gastrectomy ◽  
Scoring System ◽  
The Elderly

Laparoscopic gastrectomy for gastric cancer in the elderly patients

2015 ◽  
Vol 30 (4) ◽  
pp. 1380-1387 ◽  
Author(s):  
Muneharu Fujisaki ◽  
Toshihiko Shinohara ◽  
Nobuyoshi Hanyu ◽  
Susumu Kawano ◽  
Yujiro Tanaka ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Laparoscopic Gastrectomy ◽  
The Elderly

scholarly journals Erratum to: Laparoscopic gastrectomy for gastric cancer in the elderly patients

2016 ◽  
Vol 31 (6) ◽  
pp. 2706-2709
Author(s):  
Muneharu Fujisaki ◽  
Toshihiko Shinohara ◽  
Nobuyoshi Hanyu ◽  
Susumu Kawano ◽  
Yujiro Tanaka ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Laparoscopic Gastrectomy ◽  
The Elderly

scholarly journals Survival Based On The Pathologic Lymph Node Ratio For Local Advanced Gastric Cancer; Elderly Patients Versus Non Elderly Patients

2021 ◽  
Author(s):  
Omer Yalkin ◽  
Nidal Iflazoglu ◽  
Olgun Deniz ◽  
Mustafa Yener Uzunoglu ◽  
Ezgi Isil Turhan
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Elderly Patients ◽  
Advanced Gastric Cancer ◽  
Lymph Node Ratio ◽  
Locally Advanced ◽  
Survival Rates ◽  
The Elderly ◽  
Survival Difference ◽  
Node Ratio

Abstract Objective: The aim of this study was to clarify the prognostic value of the pathological lymph node ratio for elderly and non-elderly gastric cancer patients and to evaluate whether there is a difference in the survival of patients with the same LNR (Lymph Node Ratio).Materials and Methods: A total of 222 patients diagnosed with locally advanced gastric cancer and who underwent gastrectomy were included. The patients were divided into two groups according to age. Clinicopathological properties of the two groups were compared. Potential prognostic factors affecting survival were analyzed. Subsequently, the effect of lymphadenectomy and LNR on survival in both groups was evaluated. Results: Significant differences were detected in terms of the location of primary lesions, hemoglobin and albumin levels between elderly patients and non-elderly patients (p < .05). Overall survival (OS) was significantly worse in elderly patients (22 months vs. 67 months, p<0.001). The survival rates in elderly patients were significantly lower from those of non-elderly in the subgroup LNR Stage 2 (12.1% vs. 47.9 %, P = 0.004) and LNR Stage 3 classification (9.1% vs. 34.1%, P = 0.039). LNR was found to be significant for OS with a cut-off point of 0.18. Conclusion: A survival difference was found between the elderly and non-elderly patients with the same LNR. LNR was found to be an independent factor for survival especially in elderly patients. Survival was found to be further decreased in elderly patients compared to non-elderly patients with increasing LNR.

Is Laparoscopic Gastrectomy More Advantageous for Elderly Patients Than for Young Patients with Resectable Advanced Gastric Cancer?

2020 ◽  
Vol 44 (7) ◽  
pp. 2332-2339
Author(s):  
Yuki Ushimaru ◽  
Yukinori Kurokawa ◽  
Tsuyoshi Takahashi ◽  
Takuro Saito ◽  
Kotaro Yamashita ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Advanced Gastric Cancer ◽  
Laparoscopic Gastrectomy ◽  
Young Patients

scholarly journals Results of Treatment of Locally advanced Gastric Cancer in the Elderly Patients

2012 ◽  
Vol 23 ◽  
pp. ix229
Author(s):  
D. Egamberdiev ◽  
M. Djuraev ◽  
S. Khudayorov ◽  
O. Nematov ◽  
A. Babaev ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Advanced Gastric Cancer ◽  
Locally Advanced ◽  
The Elderly ◽  
Results Of Treatment ◽  
Locally Advanced Gastric Cancer

Chemotherapy and survival benefit in elderly patients with advanced gastric cancer.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 45-45 ◽  
Author(s):  
Aya Sugimoto ◽  
Tsutomu Nishida ◽  
Kei Takahashi ◽  
Kaori Mukai ◽  
Tokuhiro Matsubara ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Advanced Gastric Cancer ◽  
Scoring System ◽  
Survival Benefit ◽  
Poor Prognosis ◽  
Risk Group ◽  
Univariate Analysis ◽  
Significant Difference ◽  
Total Point

45 Background:There is little evidence if chemotherapy (CT) offer survival benefit for elderly patients (EP) with advanced gastric cancer (AGC). Methods: This was a single-centre retrospective study. A total of 118 patients with AGC were hospitalized at our hospital from April 2012 to June 2016. Of them, EP older than 75 years with AGC were eligible for inclusion in the study. Basically, the treatment strategy, chemotherapy (CT) or best supportive care (BSC) were comprehensively decided according to their background. We evaluate the risk factors for survival using the Cox proportional hazard model and explored the optimal indication for CT for EP. Results: Of 118 patients with AGC, 47 patients were enrolled as EP [63% men; mean age, 81 years]. Of EP, 26 patients (55%) received CT and 21 patients received BSC. As first-line CT, 13 patients received S1 monotherapy, the others treated with combination agents. The median overall survival time (MST) was 138 days. There was no significant difference between CT and BSC group (172 vs. 118 days, p = 0. 1087). Univariate analysis revealed the following 5 factors for poor prognosis were significant (defined as p-value < 0.1): Performance status (PS) 3a 2 (HR3.7, 95% CI: 1.5-8.5), C-reactive protein levels 3a 1mg/dL (HR4.0, 95% CI: 1.8-9.4), albumin level < 3g/dL (HR2.1, 95% CI: 1.1-4.3), neutrophil/lymphocyte ratio (NLR) 3a 4 (HR3.7, 95% CI: 1.7-8.5), and diffuse type (HR1.8, 95% CI: 0.9-3.8). As each poor risk factor of 5 and age factor 3a 80 years represents point 1, we calculated total points (0-6) for each patient. Median total points of CT and BSC were 2 and 4, respectively (p = 0.0196). Therefore, we set cut-off point of 3. Then, EP with a total point of 3 and more were classified as high risk group (HR: N = 25) and the others were as low risk group (LR: N = 22). There was significantly longer MST in LR than HR (all EP; 457 vs 105 days, HR: 0.23, p = 0.0002 and EP with CT; 232 vs 113 days, HR:0.26, p = 0.0085). Conclusions: Our findings using the scoring system including 6 factors suggest that EP with a total point 3 and more, were poor prognosis and may not receive benefit from CT for AGC. When judging indication for CT in EP with AGC, this scoring system may be useful, and in case of LR (total point 0-2) may be considered an indication for CT.

scholarly journals Evaluation of P-POSSUM as a Risk Prediction Model in Laparoscopic Gastrectomy of Elderly Patients with Gastric Cancer

2016 ◽  
Vol 19 (3) ◽  
pp. 97-101
Author(s):  
Hyo Jung Ko ◽  
Ki Hyun Kim ◽  
Si Hak Lee ◽  
Cheol Woong Choi ◽  
Su Jin Kim ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Elderly Patients ◽  
Prediction Model ◽  
Risk Prediction ◽  
Laparoscopic Gastrectomy ◽  
Risk Prediction Model
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