scholarly journals Laparoscopic Selective Proximal Vagotomy and Pyloroplasty for Pyloric Stenosis Caused by Duodenal Ulcer: A Case Report

2015 ◽  
Vol 40 (1) ◽  
pp. 50-54
Author(s):  
Yuichi Nakaseko ◽  
Fumiaki Yano ◽  
Nobuo Omura ◽  
Kazuto Tsuboi ◽  
Tomoyoshi Okamoto ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Case Report ◽  
Pyloric Stenosis ◽  
Selective Proximal Vagotomy

Duodenal Ulcer With Multiple Complications: Case Report

1950 ◽  
Vol 16 (1) ◽  
pp. 259-261 ◽  
Author(s):  
Elmer W. Heffernon ◽  
Allen C. Johnson
Keyword(s):  
Duodenal Ulcer ◽  
Case Report

Jejunal Perforation as a Result of Massive Gastrointestinal Bleeding from a Duodenal Ulcer

1984 ◽  
Vol 29 (2) ◽  
pp. 109-110
Author(s):  
J. N. Fox ◽  
J. W. W. Thomson
Keyword(s):  
Duodenal Ulcer ◽  
Small Intestine ◽  
Case Report ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Massive Bleeding ◽  
Spontaneous Perforation ◽  
Massive Gastrointestinal Bleeding ◽  
Upper Gastrointestinal

A complication of massive upper gastrointestinal bleeding is presented as a case report of a patient who developed a spontaneous perforation of the small intestine as a result of massive bleeding from a duodenal ulcer

scholarly journals A106 TTC7A MUTATION AND CHRONIC PRURITUS, A CASE REPORT

2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 123-124
Author(s):  
M Hensen ◽  
H Decaluwe ◽  
E Haddad ◽  
V Marchand
Keyword(s):  
Case Report ◽  
Parenteral Nutrition ◽  
Skin Biopsy ◽  
Pyloric Stenosis ◽  
Skin Disease ◽  
Treatment Options ◽  
Pneumocystis Carinii ◽  
Hematopoietic Stem ◽  
Oil Emulsion ◽  
Chronic Pruritus

Abstract Background TTC7A mutation is a rare autosomal recessive disease that can present with various phenotypes including multiple intestinal atresia (MIA), very early onset inflammatory bowel disease (VEOIBD), and profound combined immunodeficiency with hypoplastic thymus, altered T- and B-cell maturation, lymphopenia, monocytosis and agammaglobulinemia. Although TTC7A mutation mostly affects immune and gut function, it is a multisystemic disease. Chronic pruritus has not been described yet. Aims To describe the case of a child with TTC7A mutation with chronic pruritus and the potential treatment options. Methods Case report and review of literature Results We report a child with TTC7A mutation who developed severe chronic pruritus. The child presented ileal atresia and pyloric stenosis and underwent ileo-caecal resection and pyloroplasty at birth. She required a latero-lateral anastomosis between the stomach and the duodenum because of recurring pyloric stenosis and several dilatations of her ileo-colic anastomosis. She remained dependant on parenteral nutrition for most of her caloric needs. Her immune deficiency manifested with a very low lymphocyte count and low immunoglobulins. She had pneumocystis Carinii infection at 3 months of age and was put on gammaglobulin injections and pentamidine prophylaxis. At 3 years of age, she developed severe pruritus that led to skin infection and recurrent Staphylococcus Aureus sepsis. A skin biopsy revealed eczematous dermatitis with eosinophilic infiltration. Various treatments were attempted. Replacing lipid fat emulsion by fish oil emulsion in her parenteral nutrition did not improve her symptoms. Amitryptiline, gabapentine, hydroxyzine hydrochloride and levofloxacine also failed. Corticosteroids seemed to have a mild effect. A trial of Mepolizumab (anti-IL 5) was unsuccessful. At age of 4, after a sepsis treated by vancomycin, she presented with severe bullous skin disease. Skin biopsy was compatible with linear IgA bullous dermatosis. She was put on dupilumab and systemic corticosteroids. Dupilumab inhibits signaling of both IL-4 and IL-13, two cytokines involved in inflammation that contribute to atopic dermatitis. With this combination of IV steroids and dupilumab, pruritus has improved significantly. Conclusions Our patient’s evolution suggests that some TTC7A mutation can be complicated with severe pruritus and IgA linear bullosis. Skin disease, combined with immunodeficiency and the presence of a central line can lead to life threatening sepsis. Pruritus did not respond to usual treatments but improved the combination of intravenous steroids and dupilumab suggesting a role of IL-4 and IL-13 in the pathophysiology of the pruritus associated with this disease. Hematopoietic stem cell transplantation, may be an alternative solution. Funding Agencies None

scholarly journals Pyloric ulceration and stenosis in a two-year-old thoroughbred filly: a case report

2012 ◽  
Vol 51 (No. 2) ◽  
pp. 75-80 ◽  
Author(s):  
B. Bezdekova ◽  
P. Jahn ◽  
J. Mezerova
Keyword(s):  
Case Report ◽  
Pyloric Stenosis ◽  
Exploratory Laparotomy ◽  
Gastric Ulceration ◽  
Clinical Problems

The case of the two year old thoroughbred filly presented here has been diagnosed with and treated for equine gastric ulceration syndrome (EGUS). The results of her examination are documented over a five month period. The patient was finally hospitalised with acute severe colic. Absence of chronic clinical problems common for pyloric stenosis can be attributed to the permanent antiulceration medication of the filly. The diagnosis of pyloric stenosis was made by exploratory laparotomy and confirmed by necropsy.

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