Developing Client-Side Mashups

2013 ◽  
Vol 5 (1) ◽  
pp. 34-52
Author(s):  
Arto Salminen ◽  
Tommi Mikkonen ◽  
Feetu Nyrhinen ◽  
Antero Taivalsaari
Keyword(s):  
Software Development ◽  
Web Sites ◽  
Reference Architecture ◽  
Web Based ◽  
Starting Point ◽  
Practical Experiences ◽  
Client Side ◽  
Insight Into

Software mashups that combine content from multiple web sites to an integrated experience are a popular trend. However, methods, tools and architectures for creating mashups are still rather undeveloped, and there is little engineering support behind them. In this paper the authors present guidelines that can serve as a helpful starting point for the design of new mashups. Guidelines focus mainly on mashup creation methods. Furthermore, they describe a reference architecture for client-side mashup development. In addition, the authors provide insight into mashup development based on their practical experiences in implementing various sample client-side mashup applications and tools for creating them. The long term goal of the authors’ work is to facilitate the development of compelling, robust and maintainable mashup applications, and more generally ease the transition towards web-based software development.

Thermoanalytical methods applied to medicine

2009 ◽  
Vol 81 (10) ◽  
pp. 1881-1888 ◽  
Author(s):  
Beverley D. Glass ◽  
Michael E. Brown
Keyword(s):  
Clinical Implications ◽  
Collagen Structure ◽  
Drug Penetration ◽  
Scanning Calorimetry ◽  
Disease States ◽  
Therapeutic Outcomes ◽  
Starting Point ◽  
Thermal Stability Of ◽  
Insight Into

Thermoanalytical methods have found increasing application in medicine due to the improved sensitivity and usability of the available instrumentation. Studies have identified important findings applied to medicine, including information on the thermal properties of the skin and the effect of insertion into body cavities of implants and prosthetics. These studies have explored the thermal stability of various materials to provide insight into drug penetration in order to design drug delivery systems, which are not only safe but capable of delivering improved and predictable therapeutic outcomes for patients. Differential scanning calorimetry (DSC) has also been applied to the study of disease states such as diabetes, where changes in the collagen structure of the skin which may lead to long-term complications in these patients, can be detected. Although these results may at this stage not have significant clinical implications, they do provide medical researchers with a starting point for future investigations. The application of these techniques has been further extended to examinations of body systems and other disease states. The key for the future will be the ability of these techniques not only to provide information on alterations in these biological systems, but also to determine whether these alterations are clinically relevant.

scholarly journals VOLPES: an interactive web-based tool for visualizing and comparing physicochemical properties of biological sequences

2019 ◽  
Vol 47 (W1) ◽  
pp. W632-W635 ◽  
Author(s):  
Lukas Bartonek ◽  
Bojan Zagrovic
Keyword(s):  
Nucleic Acids ◽  
Physicochemical Properties ◽  
Sequence Data ◽  
Structural Disorder ◽  
Biological Sequence ◽  
Web Based ◽  
Starting Point ◽  
User Friendly ◽  
Insight Into ◽  
Sequence Position

Abstract The structure, dynamics and, ultimately, biological function of proteins and nucleic acids are determined by the physicochemical properties of their primary sequences. Such properties are frequently captured via one-dimensional profile plots depicting a given physicochemical variable as a function of sequence position. Hydrophobicity, charge or structural disorder in proteins or nucleobase-density in nucleic acids are routinely visualized in this manner to analyze sequences at a glance. Such visualizations, however, are typically created case-by-case in a purely static manner, employ fixed visualization parameters only and do not enable a quantitative comparison between different sequences. Here, we present VOLPES (volpes.univie.ac.at), a user-friendly web server and the corresponding JavaScript library that enable a fully interactive, multifunctional visualization, analysis and comparison of the physicochemical properties of protein and nucleic-acid sequences, allowing unprecedented insight into biological sequence data and creating a starting point for further in-depth exploration.

scholarly journals Vpliv epidemije COVID-19 na odpis blaga v podjetju za distribucijo sadja in zelenjave

2021 ◽  
Author(s):  
Alma Ramčilović Jesih
Keyword(s):  
Work Processes ◽  
Significant Cost ◽  
Factors Influencing ◽  
Fresh Food ◽  
Starting Point ◽  
Distribution Company ◽  
Reducing Costs ◽  
The Impact ◽  
Insight Into

The write-off of goods, especially in the fresh food supply chain, represents a significant cost to the company. The purpose of the research is to analyse the impact of the COVID19 epidemic in the fruit and vegetable distribution company and to determine the extent to which the epidemic in 2020 affected the company's operations and the amount of goods written off. Knowing the latter is the first step to improving processes and reducing costs in the company. The analysis was performed using a comparative study of data for 2019 and 2020. The total weight of goods sold in 2020 compared to 2019 fell by 28.6%. Similarly, in 2020 the total value of written-off goods decreased by 31.3%. Furthermore, factors influencing the value of writtenoff goods, such as the purchase value of products, the number of products, the number of orders per day and the number of employees (order preparation and weighting) were studied statistically. We found a relationship between the value of written-off goods and the number of employees and the number of products being prepared. The results represent an insight into the problem and serve as a starting point for optimizing the purchase of goods, the correct turning of stocks and work processes of employees in the warehouse, i.e. optimization of logistics processes in the company. Reducing the quantity of written-off goods is a long-term and demanding process, which significantly improves the company's profit.

scholarly journals Effects of a web-based rehabilitation aftercare on subjective health, work ability and motivation: a partially randomized controlled trial

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Darko Jekauc ◽  
Sabine Rayling ◽  
Sara Klopp ◽  
Detlef Schmidt ◽  
Lena-Marie Rittmann ◽  
...  
Keyword(s):  
Work Ability ◽  
Subjective Health ◽  
Control Group ◽  
Valuable Insight ◽  
Rehabilitation Center ◽  
Web Based ◽  
Face To Face ◽  
Insight Into ◽  
Rehabilitation Aftercare

Abstract Background Rehabilitation is seen as crucial in dealing with the demographic change in many European countries. In Germany, for example, after having stayed in a rehabilitation center, patients have the possibility to participate in aftercare programs aimed at promoting long-term health behaviour. Despite the relevance of follow-up support for patients’ long-term health and work ability, participation rates in aftercare programs are quite low. Here, web-based aftercare programs can be a viable alternative to the traditional face-to-face programs due to their flexibility in time and location. This research project aims to use quantitative and qualitative methods to gain more insight into the potential of web-based aftercare programs. Methods The goal is to recruit up to 1150 patients at baseline in five rehabilitation centers across Germany. For ethical reasons, partially randomized experimental study design is used to quantitatively assess the effectiveness of web-based aftercare programs. All patients are offered the traditional face-to-face aftercare treatment (IRENA). When patients deny to participate in traditional face-to-face aftercare, they are randomly distributed into either web-based aftercare (digIRENA) or a control group. In all three groups, the SF-12, which measures subjective health, and the WAI, which measures working ability, will be used at baseline, 13 weeks, 26 weeks and 43 weeks after the patients have left the rehabilitation center. BREQ-2, which measures motivation, is used only in the traditional aftercare group and the web-based aftercare group. A multivariate analysis of variance with repeated measurement and latent growth curve models will be used to compare the development of the variables in the three groups. For the qualitative part of the study, interviews with patients and therapists will be conducted to shed light on the applicability, acceptance, and usability of web-based aftercare programs. Discussion This study may provide valuable insight into the potential of web-based rehabilitation aftercare programs as a way to supplement traditional face-to-face programs. This seems particularly promising if it can manage to reach those patients who do not currently participate in traditional face-to-face rehabilitation aftercare programs due to time and location constraints. Trial registration The trial has been registered at the German Register of Clinical Studies (DRKS) with the registration number: DRKS00022467.

Turkish Muslims in a German city: Entrepreneurial and residential self-determination

2015 ◽  
Vol 12 (1) ◽  
pp. 1-12
Author(s):  
Sarah Hackett
Keyword(s):  
Residential Patterns ◽  
Academic Literature ◽  
Self Employment ◽  
German City ◽  
Post War ◽  
Oral History Interviews ◽  
The City ◽  
Insight Into ◽  
Term Objective

Drawing upon a collection of oral history interviews, this paper offers an insight into entrepreneurial and residential patterns and behaviour amongst Turkish Muslims in the German city of Bremen. The academic literature has traditionally argued that Turkish migrants in Germany have been pushed into self-employment, low-quality housing and segregated neighbourhoods as a result of discrimination, and poor employment and housing opportunities. Yet the interviews reveal the extent to which Bremen’s Turkish Muslims’ performances and experiences have overwhelmingly been the consequences of personal choices and ambitions. For many of the city’s Turkish Muslim entrepreneurs, self-employment had been a long-term objective, and they have succeeded in establishing and running their businesses in the manner they choose with regards to location and clientele, for example. Similarly, interviewees stressed the way in which they were able to shape their housing experiences by opting which districts of the city to live in and by purchasing property. On the whole, they perceive their entrepreneurial and residential practices as both consequences and mediums of success, integration and a loyalty to the city of Bremen. The findings are contextualised within the wider debate regarding the long-term legacy of Germany’s post-war guest-worker system and its position as a “country of immigration”.

The Word Class Adjective in English Business Magazines Online

2018 ◽  
Vol 6 (2) ◽  
pp. 99-115
Author(s):  
Borislav Marušić ◽  
Sanda Katavić-Čaušić
Keyword(s):  
Empirical Study ◽  
Empirical Analysis ◽  
Word Formation ◽  
Word Class ◽  
Business English ◽  
Starting Point ◽  
Comprehensive Picture ◽  
English Syntax ◽  
The Empirical Analysis ◽  
Insight Into

Abstract The aim of this paper is to research the word class adjective in one sequence of the ESP: Business English, more precisely English business magazines online. It is an empirical study on the corpus taken from a variety of business magazines online. The empirical analysis allows a comprehensive insight into the word class adjective in this variety of Business English and makes its contribution to English syntax, semantics and word formation. The syntactic part analyses the adjective position in the sentence. The semantic part of the study identifies the most common adjectives that appear in English business magazines online. Most of the analysis is devoted to the word formation of the adjectives found in the corpus. The corpus is analysed in such a way that it enables its division into compounds, derivatives and conversions. The results obtained in this way will give a comprehensive picture of the word class adjective in this type of Business English and can act as a starting point for further research of the word class adjective.

PubChem and ChEMBL Beyond Lipinski

2019 ◽  
Author(s):  
Jean-Louis Reymond ◽  
Mahendra Awale ◽  
Daniel Probst ◽  
Alice Capecchi
Keyword(s):  
Nearest Neighbor ◽  
Molecular Shape ◽  
Biological Properties ◽  
Web Based ◽  
Large Molecules ◽  
Interactive Tools ◽  
Small Molecule Drugs ◽  
Pubchem Database ◽  
Nearest Neighbor Searches ◽  
Insight Into

<p>Seven million of the currently 94 million entries in the PubChem database break at least one of the four Lipinski constraints for oral bioavailability, 183,185 of which are also found in the ChEMBL database. These non-Lipinski PubChem (NLP) and ChEMBL (NLC) subsets are interesting because they contain new modalities that can display biological properties not accessible to small molecule drugs. Unfortunately, the current search tools in PubChem and ChEMBL are designed for small molecules and are not well suited to explore these subsets, which therefore remain poorly appreciated. Herein we report MXFP (macromolecule extended atom-pair fingerprint), a 217-D fingerprint tailored to analyze large molecules in terms of molecular shape and pharmacophores. We implement MXFP in two web-based applications, the first one to visualize NLP and NLC interactively using Faerun (http://faerun.gdb.tools/), the second one to perform MXFP nearest neighbor searches in NLP (http://similaritysearch.gdb.tools/). We show that these tools provide a meaningful insight into the diversity of large molecules in NLP and NLC. The interactive tools presented here are publicly available at http://gdb.unibe.ch and can be used freely to explore and better understand the diversity of non-Lipinski molecules in PubChem and ChEMBL.</p>

Research for a sustainable European sugar sector

2010 ◽  
pp. 487-495
Author(s):  
Martin Bruhns ◽  
Peter Glaviè ◽  
Arne Sloth Jensen ◽  
Michael Narodoslawsky ◽  
Giorgio Pezzi ◽  
...  
Keyword(s):  
Sugar Industry ◽  
Research Priorities ◽  
Decision Makers ◽  
Sustainable Chemistry ◽  
Technology Platforms ◽  
Research Themes ◽  
Starting Point ◽  
Manufacturing Applications ◽  
European Technology

The paper is based on the results of international project entitled “Towards Sustainable Sugar Industry in Europe (TOSSIE)”. 33 research topics of major importance to the sugar sector are listed and briefly described, and compared with research priorities of the European Technology Platforms: “Food for Life”, “Sustainable Chemistry”, “Biofuels”, and “Plant for the Future”. Most topics are compatible with the research themes included in the COOPERATION part of the 7th Framework Program of the EU (2007-2013). However, some topics may require long-term R&D with the time horizon of up to 15 years. The list of topics is divided into four parts: Sugar manufacturing, Applications of biotechnology and biorefinery processing, Sugarbeet breeding and growing, Horizontal issues. Apart from possible use of the list by policy- and decision makers with an interest in sugarbeet sector, the description of each research topic can be used as a starting point in setting up a research project or other R&D activities.

Design and Development of a Web-based Delirium Preventive Application for Long-term Care Facilities: A Methodological Study (Preprint)

2020 ◽  
Author(s):  
Kyoung Ja Moon ◽  
Chang-Sik Son ◽  
Jong-Ha Lee ◽  
Mina Park
Keyword(s):  
Risk Factors ◽  
Long Term Care ◽  
Cloud System ◽  
Evidence Based ◽  
Methodological Study ◽  
Term Care ◽  
Web Based ◽  
Care Facilities ◽  
Delirium Prevention

BACKGROUND Long-term care facilities demonstrate low levels of knowledge and care for patients with delirium and are often not properly equipped with an electronic medical record system, thereby hindering systematic approaches to delirium monitoring. OBJECTIVE This study aims to develop a web-based delirium preventive application (app), with an integrated predictive model, for long-term care (LTC) facilities using artificial intelligence (AI). METHODS This methodological study was conducted to develop an app and link it with the Amazon cloud system. The app was developed based on an evidence-based literature review and the validity of the AI prediction model algorithm. Participants comprised 206 persons admitted to LTC facilities. The app was developed in 5 phases. First, through a review of evidence-based literature, risk factors for predicting delirium and non-pharmaceutical contents for preventive intervention were identified. Second, the app, consisting of several screens, was designed; this involved providing basic information, predicting the onset of delirium according to risk factors, assessing delirium, and intervening for prevention. Third, based on the existing data, predictive analysis was performed, and the algorithm developed through this was calculated at the site linked to the web through the Amazon cloud system and sent back to the app. Fourth, a pilot test using the developed app was conducted with 33 patients. Fifth, the app was finalized. RESULTS We developed the Web_DeliPREVENT_4LCF for patients of LTC facilities. This app provides information on delirium, inputs risk factors, predicts and informs the degree of delirium risk, and enables delirium measurement or delirium prevention interventions to be immediately implemented with a verified tool. CONCLUSIONS This web-based application is evidence-based and offers easy mobilization and care to patients with delirium in LTC facilities. Therefore, the use of this app improves the unrecognized of delirium and predicts the degree of delirium risk, thereby helping initiatives for delirium prevention and providing interventions. This would ultimately improve patient safety and quality of care. CLINICALTRIAL none

Moving Songs

2019 ◽  
pp. 590-606
Author(s):  
Sally Treloyn ◽  
Matthew Dembal Martin ◽  
Rona Goonginda Charles
Keyword(s):  
Cultural Heritage ◽  
Knowledge Transmission ◽  
Intercultural Relationships ◽  
Cultural Negotiation ◽  
Intercultural Collaboration ◽  
Present Collection ◽  
Intergenerational Knowledge ◽  
Early Phases ◽  
Insight Into

Repatriation has become almost ubiquitous in ethnomusicological research on Australian Indigenous song. This article provides insights into processes of a repatriation-centered song revitalization project in the Kimberley, northwest Australia. Authored by an ethnomusicologist and two members of the Ngarinyin cultural heritage community, the article provides firsthand accounts of the early phases of a long-term repatriation-centered project referred to locally as the Junba Project. The authors provide a sample of narratives and dialogues that deliver insight into experiences of the work of identifying recordings “in the archive” and cultural negotiation and use of recordings “on Country.” The entanglement of local epistemological frameworks with past and present collection, archival research, repatriation, and dissemination for intergenerational knowledge transmission between spirits, Country, and the living, is explored, showing how recordings move song knowledge from community to archive to community and from generation to generation, and move people in present-day communities. The chapter considers how these “moving songs” allow an interrogation of the fraught endeavor of intercultural collaboration in the pursuit of revitalizing Indigenous song traditions. It positions repatriation as a method that can support intergenerational knowledge transmission and as a method to consider past and present intercultural relationships within research projects and between cultural heritage communities and collecting institutions.

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