5556 Intravitreal Bevacizumab Attaches To Vessel Walls, Forms Complexes Which Interact With Blood Cells, Activates Platelets And Reduces Retinal Blood Flow In Monkey And Human Eyes

SciVee ◽  
2012 ◽  
Author(s):  
Ulrich Schraermeyer ◽  
Sylvie Julien
Keyword(s):  
Blood Flow ◽  
Blood Cells ◽  
Intravitreal Bevacizumab ◽  
Retinal Blood Flow ◽  
Vessel Walls ◽  
Human Eyes

A few upstream bifurcations drive the spatial distribution of red blood cells in model microfluidic networks

Soft Matter ◽  
2022 ◽  
Author(s):  
Adlan Merlo ◽  
Maxime Berg ◽  
Paul Duru ◽  
Frédéric Risso ◽  
Yohan Davit ◽  
...  
Keyword(s):  
Blood Flow ◽  
Spatial Distribution ◽  
Blood Vessel ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Small Vessel ◽  
Microfluidic Networks ◽  
Vessel Walls ◽  
Vessel Networks

The physics of blood flow in small vessel networks is dominated by the interactions between Red Blood Cells (RBCs), plasma and blood vessel walls. The resulting couplings between the microvessel...

scholarly journals Measurement of Retinal Blood Flow Using Fluorescently Labeled Red Blood Cells

eNeuro ◽  
2015 ◽  
Vol 2 (2) ◽  
pp. ENEURO.0005-15.2015 ◽  
Author(s):  
Tess E. Kornfield ◽  
Eric A. Newman
Keyword(s):  
Blood Flow ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Retinal Blood Flow

Diabetic glycemic control and retinal blood flow

Diabetes ◽  
1990 ◽  
Vol 39 (5) ◽  
pp. 602-607 ◽  
Author(s):  
J. E. Grunwald ◽  
A. J. Brucker ◽  
S. S. Schwartz ◽  
S. N. Braunstein ◽  
L. Baker ◽  
...  
Keyword(s):  
Blood Flow ◽  
Glycemic Control ◽  
Retinal Blood Flow

Ocular and retinal blood flow

2009 ◽  
Vol 67 (S191) ◽  
pp. 15-18 ◽  
Author(s):  
D. W. Hill
Keyword(s):  
Blood Flow ◽  
Retinal Blood Flow

scholarly journals Mathematical Models for Some Aspects of Blood Microcirculation

Symmetry ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1020
Author(s):  
Angiolo Farina ◽  
Antonio Fasano ◽  
Fabio Rosso
Keyword(s):  
Blood Flow ◽  
Mathematical Models ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Blood Rheology ◽  
Small Class ◽  
Small Vessels ◽  
Blood Microcirculation ◽  
Peculiar Behavior

Blood rheology is a challenging subject owing to the fact that blood is a mixture of a fluid (plasma) and of cells, among which red blood cells make about 50% of the total volume. It is precisely this circumstance that originates the peculiar behavior of blood flow in small vessels (i.e., roughly speaking, vessel with a diameter less than half a millimeter). In this class we find arteriolas, venules, and capillaries. The phenomena taking place in microcirculation are very important in supporting life. Everybody knows the importance of blood filtration in kidneys, but other phenomena, of not less importance, are known only to a small class of physicians. Overviewing such subjects reveals the fascinating complexity of microcirculation.

scholarly journals Association of ocular blood flow and contrast sensitivity in normal tension glaucoma

2021 ◽  
Author(s):  
David Kuerten ◽  
Matthias Fuest ◽  
Peter Walter ◽  
Babac Mazinani ◽  
Niklas Plange
Keyword(s):  
Blood Flow ◽  
Visual Field ◽  
Contrast Sensitivity ◽  
Visual Field Defect ◽  
Prospective Trial ◽  
Normal Tension Glaucoma ◽  
Ocular Blood Flow ◽  
Retinal Blood Flow ◽  
Control Group ◽  
Field Defect

Abstract Purpose To investigate the relationship of ocular blood flow (via arteriovenous passage time, AVP) and contrast sensitivity (CS) in healthy as well as normal tension glaucoma (NTG) subjects. Design Mono-center comparative prospective trial Methods Twenty-five NTG patients without medication and 25 healthy test participants were recruited. AVP as a measure of retinal blood flow was recorded via fluorescein angiography after CS measurement using digital image analysis. Association of AVP and CS at 4 spatial frequencies (3, 6, 12, and 18 cycles per degree, cpd) was explored with correlation analysis. Results Significant differences regarding AVP, visual field defect, intraocular pressure, and CS measurement were recorded in-between the control group and NTG patients. In NTG patients, AVP was significantly correlated to CS at all investigated cpd (3 cpd: r =  − 0.432, p< 0.03; 6 cpd: r =  − 0.629, p< 0.0005; 12 cpd: r =  − 0.535, p< 0.005; and 18 cpd: r =  − 0.58, p< 0.001), whereas no significant correlations were found in the control group. Visual acuity was significantly correlated to CS at 6, 12, and 18 cpd in NTG patients (r =  − 0.68, p< 0.002; r =  − 0.54, p< .02, and r =  − 0.88, p< 0.0001 respectively), however not in healthy control patients. Age, visual field defect MD, and PSD were not significantly correlated to CS in in the NTG group. MD and PSD were significantly correlated to CS at 3 cpd in healthy eyes (r = 0.55, p< 0.02; r =  − 0.47, p< 0.03). Conclusion Retinal blood flow alterations show a relationship with contrast sensitivity loss in NTG patients. This might reflect a disease-related link between retinal blood flow and visual function. This association was not recorded in healthy volunteers.

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