One Health and Lessons Learned from the 1999 West Nile Virus Outbreak (MWV46)

SciVee ◽  
2011 ◽  
Keyword(s):  
West Nile Virus ◽  
One Health ◽  
Lessons Learned ◽  
West Nile

scholarly journals Importance of Multidisciplinary and Regional Collaboration in Integrated West Nile Virus Surveillance - the „One Health” Concept

2020 ◽  
Vol 39 (2) ◽  
pp. 40-47 ◽  
Author(s):  
Tatjana Vilibić-Čavlek ◽  
Dejan Vidanović ◽  
Ljubo Barbić ◽  
Pavle Jeličić ◽  
Sava Lazić ◽  
...  
Keyword(s):  
West Nile Virus ◽  
One Health ◽  
West Nile ◽  
Virus Surveillance ◽  
Regional Collaboration ◽  
Health Concept ◽  
The One

West Nile virus (WNV) danas je jedan od najrasprostranjenijih arbovirusa. U posljednja se dva desetljeća WNV infekcije kontinuirano pojavljuju na području Europe u obliku manjih ili većih epidemija i epizootija. U ovom preglednom radu prikazujemo epidemiološke značajke WNV infekcija koje su dokazane na području Hrvatske i Srbije u kontekstu “Jednog zdravlja”. Prikazani rezultati potvrđuju značaj multidisciplinarne i regionalne suradnje u dijagnostici i praćenju ove (re-)emergentne virusne zoonoze.

scholarly journals West Nile Virus: An Update on Pathobiology, Epidemiology, Diagnostics, Control and “One Health” Implications

Pathogens ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 589 ◽  
Author(s):  
Gervais Habarugira ◽  
Willy W. Suen ◽  
Jody Hobson-Peters ◽  
Roy A. Hall ◽  
Helle Bielefeldt-Ohmann
Keyword(s):  
West Nile Virus ◽  
One Health ◽  
Antiviral Treatment ◽  
Disease Outbreaks ◽  
Economic Losses ◽  
West Nile ◽  
Animal Products ◽  
Health Implications ◽  
Natural Hosts ◽  
Control Programmes

West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe, lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its discovery, WNV has caused multiple human and animal disease outbreaks in all continents, except Antarctica. Infections are associated with economic losses, mainly due to the cost of treatment of infected patients, control programmes, and loss of animals and animal products. The pathogenesis of WNV has been extensively investigated in natural hosts as well as in several animal models, including rodents, lagomorphs, birds, and reptiles. However, most of the proposed pathogenesis hypotheses remain contentious, and much remains to be elucidated. At the same time, the unavailability of specific antiviral treatment or effective and safe vaccines contribute to the perpetuation of the disease and regular occurrence of outbreaks in both endemic and non-endemic areas. Moreover, globalisation and climate change are also important drivers of the emergence and re-emergence of the virus and disease. Here, we give an update of the pathobiology, epidemiology, diagnostics, control, and “One Health” implications of WNV infection and disease.

scholarly journals Economics of One Health: Evidence of substantial benefits of integrated West Nile virus surveillance

2016 ◽  
Vol 53 ◽  
pp. 33
Author(s):  
G. Paternoster ◽  
S. Babo Martins ◽  
A. Mattivi ◽  
R. Cagarelli ◽  
P. Angelini ◽  
...  
Keyword(s):  
West Nile Virus ◽  
One Health ◽  
West Nile ◽  
Virus Surveillance

Meeting the challenge of bioterrorism: Lessons learned from West Nile virus and anthrax

2003 ◽  
Vol 21 (1) ◽  
pp. 77-79 ◽  
Author(s):  
Robert S. Crupi ◽  
Deborah S. Asnis ◽  
Christopher C. Lee ◽  
Thomas Santucci ◽  
Mark J. Marino ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Lessons Learned ◽  
West Nile

scholarly journals The Degree of One Health Implementation in the West Nile Virus Integrated Surveillance in Northern Italy, 2016

2017 ◽  
Vol 5 ◽  
Author(s):  
Giulia Paternoster ◽  
Laura Tomassone ◽  
Marco Tamba ◽  
Mario Chiari ◽  
Antonio Lavazza ◽  
...  
Keyword(s):  
West Nile Virus ◽  
One Health ◽  
Northern Italy ◽  
The West ◽  
West Nile

scholarly journals A Plant-Produced Virus-Like Particle Displaying Envelope Protein Domain III Elicits an Immune Response Against West Nile Virus in Mice

2021 ◽  
Vol 12 ◽  
Author(s):  
Jennifer Stander ◽  
Aleyo Chabeda ◽  
Edward P. Rybicki ◽  
Ann E. Meyers
Keyword(s):  
West Nile Virus ◽  
Envelope Protein ◽  
One Health ◽  
Vaccine Candidate ◽  
Protein Domain ◽  
West Nile ◽  
Health Initiative ◽  
Virus Like Particle ◽  
The One ◽  
Domain Iii

West Nile virus (WNV) is a globally disseminated Flavivirus that is associated with encephalitis outbreaks in humans and horses. The continuous global outbreaks of West Nile disease in the bird, human, and horse populations, with no preventative measures for humans, pose a major public health threat. The development of a vaccine that contributes to the “One Health” Initiative could be the answer to prevent the spread of the virus and control human and animal disease. The current commercially available veterinary vaccines are generally costly and most require high levels of biosafety for their manufacture. Consequently, we explored making a particulate vaccine candidate made transiently in plants as a more cost-effective and safer means of production. A WNV virus-like particle-display-based vaccine candidate was generated by the use of the SpyTag/SpyCatcher (ST/SC) conjugation system. The WNV envelope protein domain III (EDIII), which contains WNV-specific epitopes, was fused to and displayed on AP205 phage virus-like particles (VLPs) following the production of both separately in Nicotiana benthamiana. Co-purification of AP205 and EDIII genetically fused to ST and SC, respectively, resulted in the conjugated VLPs displaying EDIII with an average coupling efficiency of 51%. Subcutaneous immunisation of mice with 5 μg of purified AP205: EDIII VLPs elicited a potent IgG response to WNV EDIII. This study presents the potential plants being used as biofactories for making significant pharmaceutical products for the “One Health” Initiative and could be used to address the need for their local production in low- and middle-income countries (LMICs).

scholarly journals Economics of One Health: Costs and benefits of integrated West Nile virus surveillance in Emilia-Romagna

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0188156 ◽  
Author(s):  
Giulia Paternoster ◽  
Sara Babo Martins ◽  
Andrea Mattivi ◽  
Roberto Cagarelli ◽  
Paola Angelini ◽  
...  
Keyword(s):  
West Nile Virus ◽  
One Health ◽  
Health Costs ◽  
Costs And Benefits ◽  
West Nile ◽  
Virus Surveillance
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