scholarly journals Anti-Inflammatory Effect of Asterias amurensis Fatty Acids through NF-��B and MAPK Pathways against LPS-Stimulated RAW264.7 Cells

2018 ◽  
Vol 28 (10) ◽  
pp. 1635-1644 ◽  
Author(s):  
Chaiwat Monmai ◽  
Seok Hyeon Go ◽  
Il-shik Shin ◽  
SangGuan You ◽  
Dae-ok Kim ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Raw264.7 Cells ◽  
Asterias Amurensis ◽  
Mapk Pathways ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Anti-inflammatory Effect of Allium hookeri Root Methanol Extract in LPS-induced RAW264.7 Cells

2012 ◽  
Vol 41 (11) ◽  
pp. 1645-1648 ◽  
Author(s):  
Chang-Hyun Kim ◽  
Mi-Ai Lee ◽  
Tae-Woon Kim ◽  
Ja Young Jang ◽  
Hyun Ju Kim
Keyword(s):  
Methanol Extract ◽  
Raw264.7 Cells ◽  
Allium Hookeri ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti-Inflammatory Effect of the Extracts from Abeliophyllum distichum Nakai in LPS-Stimulated RAW264.7 Cells

2014 ◽  
Vol 27 (3) ◽  
pp. 209-214 ◽  
Author(s):  
Gwang Hun Park ◽  
Jae Ho Park ◽  
Hyun Ji Eo ◽  
Hun Min Song ◽  
Man Hyo Lee ◽  
...  
Keyword(s):  
Raw264.7 Cells ◽  
Anti Inflammatory ◽  
Abeliophyllum Distichum ◽  
Inflammatory Effect

Anti-Inflammatory Effect of Sargassum patens C. Agardh Ethanol Extract in LPS-induced RAW264.7 Cells and Mouse Ear Edema

2017 ◽  
Vol 45 (2) ◽  
pp. 110-117 ◽  
Author(s):  
Min-Ji Kim ◽  
Min-Ju Kim ◽  
Koth Bong Woo Ri Kim ◽  
Sun Hee Park ◽  
Hyeun Deok Choi ◽  
...  
Keyword(s):  
Ethanol Extract ◽  
Raw264.7 Cells ◽  
Ear Edema ◽  
Mouse Ear ◽  
Anti Inflammatory ◽  
Sargassum Patens ◽  
Mouse Ear Edema ◽  
Inflammatory Effect

scholarly journals The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection

Biomedicines ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 306 ◽  
Author(s):  
Francesca Oppedisano ◽  
Roberta Macrì ◽  
Micaela Gliozzi ◽  
Vincenzo Musolino ◽  
Cristina Carresi ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Vascular Reactivity ◽  
Molecular Mechanisms ◽  
Antioxidant Properties ◽  
Cardiac Cells ◽  
Membrane Phospholipids ◽  
Mitochondrial Functions ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Polyunsaturated fatty acids (n-3 PUFAs) are long-chain polyunsaturated fatty acids with 18, 20 or 22 carbon atoms, which have been found able to counteract cardiovascular diseases. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in particular, have been found to produce both vaso- and cardio-protective response via modulation of membrane phospholipids thereby improving cardiac mitochondrial functions and energy production. However, antioxidant properties of n-3 PUFAs, along with their anti-inflammatory effect in both blood vessels and cardiac cells, seem to exert beneficial effects in cardiovascular impairment. In fact, dietary supplementation with n-3 PUFAs has been demonstrated to reduce oxidative stress-related mitochondrial dysfunction and endothelial cell apoptosis, an effect occurring via an increased activity of endogenous antioxidant enzymes. On the other hand, n-3 PUFAs have been shown to counteract the release of pro-inflammatory cytokines in both vascular tissues and in the myocardium, thereby restoring vascular reactivity and myocardial performance. Here we summarize the molecular mechanisms underlying the anti-oxidant and anti-inflammatory effect of n-3 PUFAs in vascular and cardiac tissues and their implication in the prevention and treatment of cardiovascular disease.

scholarly journals MiR-155/GSK-3β mediates anti-inflammatory effect of Chikusetsusaponin IVa by inhibiting NF-κB signaling pathway in LPS-induced RAW264.7 cell

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Yi Xin ◽  
Qin Yuan ◽  
Chaoqi Liu ◽  
Changcheng Zhang ◽  
Ding Yuan
Keyword(s):  
Signaling Pathway ◽  
Mouse Liver ◽  
Inflammatory Responses ◽  
Biological Activities ◽  
Raw264.7 Cells ◽  
Inflammation Model ◽  
Raw264.7 Cell ◽  
Anti Inflammatory ◽  
Gsk 3Β ◽  
Inflammatory Effect

Abstract It has been demonstrated that Chikusetsusaponin IVa (CsIVa) possesses abundant biological activities. Herein, using LPS to establish acute inflammation model of mouse liver and cell line inflammation model, we investigated whether miR-155/GSK-3β regulated NF-κB signaling pathway, and CsIVa exerted anti-inflammatory effects by regulating miR-155/GSK-3β signaling pathway. Our results showed that LPS induced high expression of miR-155 and miR-155 promoted macrophage activation through GSK-3β. In addition, CsIVa inhibited inflammatory responses in LPS-induced mouse liver and RAW264.7 cells. Furthermore, we demonstrated that CsIVa improved the inflammatory response in LPS-induced RAW264.7 cells by inhibiting miR-155, increasing GSK-3β expression, and inhibiting NF-κB signaling pathway. In conclusion, our study reveals that CsIVa suppresses LPS-triggered immune response by miR-155/GSK-3β-NF-κB signaling pathway.

scholarly journals Anti‐inflammatory effect of omega unsaturated fatty acids and dialysable leucocyte extracts on collagen‐induced arthritis in DBA/1 mice

2020 ◽  
Vol 101 (1-2) ◽  
pp. 55-64
Author(s):  
Pamela I. Pérez‐Martínez ◽  
Oscar Rojas‐Espinosa ◽  
Víctor G. Hernández‐Chávez ◽  
Patricia Arce‐Paredes ◽  
Sergio Estrada‐Parra
Keyword(s):  
Fatty Acids ◽  
Unsaturated Fatty Acids ◽  
Collagen Induced Arthritis ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Wood-cultivated ginseng exerts anti-inflammatory effect in LPS-stimulated RAW264.7 cells

2018 ◽  
Vol 116 ◽  
pp. 327-334 ◽  
Author(s):  
Su Bin Park ◽  
Gwang Hun Park ◽  
Yurry Um ◽  
Ha Na Kim ◽  
Hun Min Song ◽  
...  
Keyword(s):  
Raw264.7 Cells ◽  
Anti Inflammatory ◽  
Inflammatory Effect
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