scholarly journals Host Innate Immunity against Hepatitis E Virus and Viral Evasion Mechanisms

2017 ◽  
Vol 27 (10) ◽  
pp. 1727-1735 ◽  
Author(s):  
Sangmin Kang ◽  
Jinjong Myoung
Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 541 ◽  
Author(s):  
Yang Li ◽  
Changbo Qu ◽  
Peifa Yu ◽  
Xumin Ou ◽  
Qiuwei Pan ◽  
...  

Hepatitis E virus (HEV) infection represents an emerging global health issue, whereas the clinical outcomes vary dramatically among different populations. The host innate immune system provides a first-line defense against the infection, but dysregulation may partially contribute to severe pathogenesis. A growing body of evidence has indicated the active response of the host innate immunity to HEV infection both in experimental models and in patients. In turn, HEV has developed sophisticated strategies to counteract the host immune system. In this review, we aim to comprehensively decipher the processes of pathogen recognition, interferon, and inflammatory responses, and the involvement of innate immune cells in HEV infection. We further discuss their implications in understanding the pathogenic mechanisms and developing antiviral therapies.


2011 ◽  
Vol 49 (01) ◽  
Author(s):  
C Dorloff ◽  
J Hemberger ◽  
M Odenthal ◽  
H Holzmann ◽  
S Aberle ◽  
...  

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
S Schlosser ◽  
J Pflaum ◽  
K Weigand ◽  
JJ Wenzel ◽  
W Jilg ◽  
...  

2018 ◽  
Vol 56 (01) ◽  
pp. E2-E89
Author(s):  
D Westhölter ◽  
J Hartl ◽  
J Hiller ◽  
U Denzer ◽  
S Peine ◽  
...  

1995 ◽  
Vol 74 (05) ◽  
pp. 1385-1386 ◽  
Author(s):  
Pirkko Pohjanpelto ◽  
Freja Ebeling ◽  
Vesa Rasi ◽  
Hartmut Hampl

Author(s):  
C. Kasorndorkbua ◽  
P. J. Thomas ◽  
Patrick G. Halbur ◽  
D. K. Guenette ◽  
F. F. Huang ◽  
...  

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